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SLC26A6 Proteine (SLC26A6)

Bezeichnung:
Solute Carrier Family 26, Member 6 Proteine (SLC26A6)
Auf www.antikoerper-online.de finden Sie aktuell 8 Solute Carrier Family 26, Member 6 (SLC26A6) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SLC26A6 Antikörper (43) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 57 SLC26A6 Produkte verfügbar.
Synonyme:
B930010B04Rik, CFEX, MGC81960, MGC145603, Pat1, si:dkey-20d21.8, slc26a6, zgc:175226
alle Proteine anzeigen Gen GeneID UniProt
Ratte SLC26A6 SLC26A6 301010  
SLC26A6 65010 Q9BXS9
SLC26A6 171429  

Weitere Synonyme anzeigen

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Weitere Proteine zu SLC26A6 Interaktionspartnern

Zebrafish Solute Carrier Family 26, Member 6 (SLC26A6) Interaktionspartner

Human Solute Carrier Family 26, Member 6 (SLC26A6) Interaktionspartner

  1. IL-4 (zeige IL4 Proteine) induces demethylation of specific CpG sites within the pendrin (zeige SLC26A4 Proteine) promoter. These epigenetic alterations are cell type specific, and may in part dictate pendrin (zeige SLC26A4 Proteine) mRNA transcription

  2. Helicobacter pylori infection impairs the expressions and functional activities of duodenal mucosal bicarbonate transport proteins, CFTR (zeige CFTR Proteine) and SLC26A6, which contributes to the development of duodenal ulcer.

  3. Molecular dynamics simulations of the STAS domains of rat prestin (zeige SLC26A5 Proteine) and human pendrin (zeige SLC26A4 Proteine) reveal conformational motions in conserved flexible regions.

  4. Data show that SLC26A6 variants do not alter the risk for the development of chronic pancreatitis.

  5. In the intestinal epithelium, PAT-1 (zeige APPBP2 Proteine) (SLC26A6) could mediate apical oxalate influx or apical oxalate efflux depending on the magnitude and direction prevailing counterion driver gradients as well as the relative affinities of the transported anions.

  6. orthologous mouse and human SLC26A6 proteins differ in anion selectivity, transport mechanism, and acute regulation, but both mediate electroneutral Cl(-)/HCO(3)(-) exchange

  7. In human kidney SLC26A6 and A7 have a distinct, partially overlapping expression in distal segments of nephrons. The distribution partly differs from that found previously in rodent kidneys.

  8. findings indicate that slc26a6 functions as a coupled 1Cl-/2HCO3- exchanger

  9. Mouse Slc26a6 and human SLC26A6 each mediated electroneutral Cl-/HCO3- and Cl-/OH- exchange. But, whereas Cl-/oxalate exchange by mouse Slc26a6 was electrogenic, that mediated by human SLC26A6 appeared electroneutral.

  10. No mutation was found in the coding regions and intron-exon boundaries of the genes for CA II (zeige CA2 Proteine), CA IV (zeige CA4 Proteine), CA XIV (zeige CA14 Proteine), kNCB1, NHE3 (zeige SLC9A3 Proteine), NHE8, NHRF1, NHRF2 and SLC26A6 amplified from genomic DNA of family members with pRTA.

Mouse (Murine) Solute Carrier Family 26, Member 6 (SLC26A6) Interaktionspartner

  1. Enzymatic deglycosylation of SLC26A6 expressed on the plasma membrane of intact cells strongly reduced oxalate transport activity.

  2. Slc26a1, Slc26a6 and Slc26a7 (zeige SLC26A7 Proteine) are novel participants in the extracellular transport of bicarbonate during enamel maturation.

  3. Results suggest that PAT1 (zeige APPBP2 Proteine) slows down APP (zeige APP Proteine) trafficking to the cell surface in primary cortical neurons

  4. Both PAT-1 and DRA significantly contribute to intestinal fluid absorption and enterocyte acid/base balance but are activated by different ion gradients.

  5. Cardiac myocytes express different isoforms of Slc26a6, which encode electrogenic Cl(-)/HCO3(-) and Cl(-)/oxalate exchangers.

  6. Slc26a6-null mice exhibited increased renal and intestinal sodium-dependent succinate uptake, as well as urinary hyperoxaluria and hypocitraturia, but no change in urinary pH, indicating enhanced transport activity of NaDC-1 (zeige SLC13A2 Proteine).

  7. NMR and CE were used to characterize the urinary metabolome in slc26a6 null mice. Clear metabolic differentiation between the urinary profiles of the slc26a6 null and the wild type mice were observed using both methods.

  8. SLC26A6 mediates 1:2 Cl-/HCO3- exchange, and the exchanger most probably upregulates SLC26A3 (zeige SLC26A3 Proteine) in its absence, therefore mediating 2:1 exchange.

  9. Data demonstrate functional Pat-1 Cl)/HCO3) exchange activity in the lower villus epithelium of the murine duodenum which, in previous studies, had been obscured by the inclusion of luminal glucose as a metabolic substrate.

  10. This study showed a functionally active CFTR (zeige CFTR Proteine) is an absolute requirement for Slc26-mediated duodenal bicarbonate secretion, but not for Slc26-mediated fluid absorption.

SLC26A6 Protein Überblick

Protein Überblick

This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Several alternatively spliced transcript variants of this gene, encoding distinct isoforms, have been described, but the full-length nature of some of these variants has not been determined.

Alternative names and synonyms associated with SLC26A6

  • solute carrier family 26 (anion exchanger), member 6 (Slc26a6)
  • solute carrier family 26, member 6 (SLC26A6)
  • solute carrier family 26, member 6 (slc26a6)
  • solute carrier family 26, member 6, like (slc26a6l)
  • solute carrier family 26 (anion exchanger), member 6 (SLC26A6)
  • solute carrier family 26, member 6 (Slc26a6)
  • B930010B04Rik Protein
  • CFEX Protein
  • MGC81960 Protein
  • MGC145603 Protein
  • Pat1 Protein
  • si:dkey-20d21.8 Protein
  • slc26a6 Protein
  • zgc:175226 Protein

Bezeichner auf Proteinebene für SLC26A6

solute carrier family 26, member 6 , solute carrier family 26 member 6 , SLC26A6a anion exchanger , slc26a6c , slc26a6b , anion transporter 1 , pendrin L1 , sulfate anion transporter

GENE ID SPEZIES
301010 Rattus norvegicus
416012 Gallus gallus
444778 Xenopus laevis
497236 Sus scrofa
514514 Bos taurus
559448 Danio rerio
608998 Canis lupus familiaris
780378 Xenopus (Silurana) tropicalis
100005108 Danio rerio
100173317 Pongo abelii
100613198 Pan troglodytes
65010 Homo sapiens
171429 Mus musculus
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