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Podoplanin Proteine (PDPN)

Bezeichnung:
Podoplanin Proteine (PDPN)
Auf www.antikoerper-online.de finden Sie aktuell 31 Podoplanin (PDPN) Proteine von 13 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Podoplanin Antikörper (416) und Podoplanin Kits (44) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 509 Podoplanin Produkte verfügbar.
Synonyme:
AGGRUS, E11, GP36, Gp38, GP40, HT1A-1, OTS-8, OTS8, PA2.26, PDPN, RANDAM-2, RTI40, T1-alpha, T1a, T1A-2, T1alpha
alle Proteine anzeigen Gen GeneID UniProt
PDPN 10630 Q86YL7
PDPN 14726 Q62011
PDPN 54320 Q64294

Weitere Synonyme anzeigen

Podoplanin Proteine (PDPN) nach Spezies

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Am meisten referenzierte Podoplanin Proteine

  1. Mouse (Murine) Podoplanin Protein expressed in HEK-293 - ABIN2666857 : Kato, Fujita, Kunita, Sato, Kaneko, Osawa, Tsuruo: Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 8 Referenzen für ABIN2666857

  2. Human Podoplanin Protein expressed in Escherichia coli (E. coli) - ABIN667074 : Wicki, Christofori: The potential role of podoplanin in tumour invasion. in British journal of cancer 2007 (PubMed)
    Zeige alle 2 Referenzen für ABIN667074

Weitere Proteine zu Podoplanin Interaktionspartnern

Human Podoplanin (PDPN) Interaktionspartner

  1. A possible crosstalk between epithelial and stromal tumor cells in hepatocellular carcinoma tumor microenvironment may be mediated by podoplanin

  2. interest, LpMab-17 did not bind to monkey PDPN, whereas the homology is 94% between human PDPN and monkey PDPN, indicating that the epitope of LpMab-17 is unique compared with the other anti-PDPN mAbs. The combination of different epitope-possessing mAbs could be advantageous for the PDPN-targeting diagnosis or therapy

  3. podoplanin expression is significantly associated with malignant transformation of chronic lip discoid lupus erythematosus into lip squamous cell carcinoma

  4. the epitope of PMab-21 was identified as Leu44-Glu48, which is corresponding to platelet aggregation-stimulating (PLAG) domain, indicating that Ser61-Ala68 of rabbit PDPN is a more appropriate epitope for immunohistochemistry compared with PLAG domain. PMab-32 could be useful for uncovering the function of rabbit PDPN

  5. NZ-1 inhibits the hPDPN-CLEC-2 (zeige CLEC1B Proteine) interaction and is also useful for anti-PA tag MAb.The minimum epitope of LpMab-13 was identified as Ala42-Asp49 of hPDPN using Western blot and flow cytometry. The combination of different epitope-possessing MAbs could be advantageous for the hPDPN-targeting diagnosis and therapy

  6. Low PDPN expression is associated with Uterine Cervical Squamous Intraepithelial Lesions.

  7. high tumoral podoplanin expression could independently predict an adverse clinical outcome for ccRCC patients, and it might be useful in future for clinical decision-making and therapeutic developments.

  8. the present results also suggest that podoplanin+ cells can function as stromal cells for blast cell retention in the AML (zeige RUNX1 Proteine) tumor microenvironment.

  9. We revealed that podoplanin expression in Cancer-associated Fibroblasts was an independent indicator of worse prognosis, irrespective of the expression status of the tumor cells in patients with squamous cell carcinoma of the lung.

  10. High podoplanin expression is associated with lymphatic spread of the breast cancer.

Mouse (Murine) Podoplanin (PDPN) Interaktionspartner

  1. Podoplanin expressed by lymphatic vessels prevents postnatal blood filling of the lymphatic vascular system and contributes to efficient dendritic cell migration to the lymph nodes.

  2. Study provides evidence that podoplanin as a novel component of the neuronal machinery underlying neuritogenesis, synaptic plasticity, and hippocampus-dependent memory functions.

  3. This study suggests that ppGalNAc-T13 (zeige GALNT13 Proteine) contributes to neuronal differentiation through glycosylating and stabilizing PDPN, which provides insights into the regulatory roles of O-glycosylation in mammalian neural development.

  4. Data show that E11/glycoprotein 38(GP38) was up-regulated upon SEMA3A (zeige SEMA3A Proteine) stimulation, and cyclin-dependent kinase 6 (CDK6 (zeige CDK6 Proteine)) was down-regulated in a time-dependent manner.

  5. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8 (zeige LGALS8 Proteine)-dependent crosstalk among VEGF-C (zeige VEGFC Proteine), podoplanin and integrin pathways plays a key role.

  6. A reciprocal interaction between CLEC-2 (zeige CLEC1B Proteine) on megakaryocytes and PDPN on Bone marrow (BM) Fibroblastic reticular cell-like cells contributes to the periarteriolar megakaryopoietic microenvironment in mouse BM.

  7. Data indicate that a mechanism reliant upon blockade of proteasome-mediated E11 destabilization contributes to osteocytogenesis and that this may involve downstream targeting of RhoA (zeige RHOA Proteine).

  8. it is likely that PDPN, while being dispensable during re-epithelialization, has a crucial role in migration and invasion of transformed keratinocytes.

  9. Report distinct podoplanin-positive stromal cell populations and a novel progenitor subset in chronic liver inflammation and fibrosis.

  10. CLEC-2 (zeige CLEC1B Proteine) is an adhesive receptor that supports platelet arrest to podoplanin under venous shear. Src (zeige SRC Proteine)/Syk (zeige SYK Proteine)-dependent signalling stabilises platelet adhesion to podoplanin.

Cow (Bovine) Podoplanin (PDPN) Interaktionspartner

  1. These results indicated that PDPN gene plays a significant role in the proliferation and maturation of bovine Sertoli cells.

Podoplanin (PDPN) Protein Überblick

Protein Überblick

This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Podoplanin (PDPN)

  • podoplanin (PDPN)
  • podoplanin (Pdpn)
  • podoplanin-like (LOC100738269)
  • AGGRUS Protein
  • E11 Protein
  • GP36 Protein
  • Gp38 Protein
  • GP40 Protein
  • HT1A-1 Protein
  • OTS-8 Protein
  • OTS8 Protein
  • PA2.26 Protein
  • PDPN Protein
  • RANDAM-2 Protein
  • RTI40 Protein
  • T1-alpha Protein
  • T1a Protein
  • T1A-2 Protein
  • T1alpha Protein

Bezeichner auf Proteinebene für Podoplanin Proteine (PDPN)

podoplanin , PA2.26 antigen , T1-alpha , glycoprotein 36 , glycoprotein, 36-KD , hT1alpha-1 , hT1alpha-2 , lung type I cell membrane associated glycoprotein , lung type-I cell membrane-associated glycoprotein (T1A-2) , aggrus , glycoprotein 38 , transmembrane glycoprotein E11 , E11 antigen epitope , RTI140 , T1A , epithelial cell surface transmembrane protein antigen , pulmonary type I alveolar epithelial cell transmembrane differentiation marker , type I cell 40 kDa protein , gp38 , mucin-type membrane protein gp40

GENE ID SPEZIES
456453 Pan troglodytes
10630 Homo sapiens
14726 Mus musculus
54320 Rattus norvegicus
403886 Canis lupus familiaris
509732 Bos taurus
101787585 Cavia porcellus
768390 Gallus gallus
101112240 Ovis aries
100738269 Sus scrofa
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