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Equine herpesvirus type 1 infection significantly decreased the expression of integrin alpha 6 in nasal mucosa epithelial cells.
Integrin alpha 6 Expression on Microglia Surface and Motility on Laminin Is Up-regulated upon Adenosine Diphosphate Stimulation.
Ahr (zeige AHR Proteine) ligand aminoflavone targets breast cancer cells with stem cell-like properties, at least in part by abolishing alpha6-integrin expression.
interaction of alpha6beta1 in embryonic stem cells (ECCs) with laminin-1 (zeige LAMA1 Proteine) activates alpha6beta1/CD151 (zeige CD151 Proteine) signaling which programs ESCs (zeige NR2E3 Proteine) toward the endothelial cells lineage fate
Exome sequencing analysis between SM/J and A/J mice identified 4 genes (Itga6, Zak (zeige ZAK Proteine), Gpr155, and Mtx2 (zeige MTX2 Proteine)) with nonsynonymous coding SNPs. These four genes might be candidate genes for type 2 diabetes caused by gene-gene interactions.
Immunohistological analysis of the tumors showed that Tie2 (zeige TEK Proteine)-dependent a6 gene deletion was associated with reduced tumor vascularization and with reduced infiltration of proangiogenic Tie2 (zeige TEK Proteine)-expressing macrophages
CD29 (zeige ITGB1 Proteine) and CD49f have a critical role of in mediating cancer metastasis.
NLGN1 (zeige NLGN1 Proteine) and alpha6 integrin preferentially colocalize in the mature retinal vessels, whereas NLGN1 (zeige NLGN1 Proteine) deletion causes an aberrant VE-cadherin (zeige CDH5 Proteine), laminin and alpha6 integrin distribution in vessels
alpha6 integrin is an essential upstream regulator of the IGF-1R (zeige IGF1R Proteine) survival pathway that regulates the activity level of caspase-3 (zeige CASP3 Proteine) for it to signal differentiation initiation of lens epithelial cells.
Deficiency of integrin alpha(6)beta(4) is modestly but significantly suppressed reporter-gene transduction by papillomaviruses in conditional integrin beta(4 (zeige ITGB4 Proteine)) knockout mice.
The alpha6beta1 integrin is a netrin-4 (zeige NTN4 Proteine) receptor in endothelial cells.
alpha6(high)/CD71 (zeige TFRC Proteine)(low) cells give rise to a thicker pluristratified epithelium with lower seeding density and display a low Ki67 (zeige MKI67 Proteine) positive cells number, showing that they have reached the balance between proliferation and differentiation.
The A380T Single Nucleotide Polymorphism of the ITGA6 gene was not associated with breast cancer development in the analyzed population of Misiones, Argentina.
Positive Thy1 (zeige THY1 Proteine) and CD49f expression is significantly associated with the progression and poor prognosis of chondrosarcoma.
Platelet-enhanced endothelial colony forming cell angiogenesis requires platelet tetraspanin CD151 (zeige CD151 Proteine) and alpha6beta1 integrin signaling.
these findings identify CD151 (zeige CD151 Proteine) and its interactions with integrins a3 and a6 as potential therapeutic targets for inhibiting stemness-driving mechanisms and stem cell populations in Glioblastoma.
HIF-dependent regulation of ITGA6 is one mechanism by which sorting for CD49f (+) cells enhances cancer stem cells.
CD49f is a marker of bone marrow mesenchymal stem cells and is correlated with changes in these stem cells under inflammatory conditions.
Genetic and Immunohistochemical Expression of Integrins ITGAV (zeige ITGAV Proteine), ITGA6, and ITGA3 (zeige ITGA3 Proteine) As Prognostic Factor for Colorectal Cancer
We here identify CD49f and CD34 (zeige CD34 Proteine) as markers to permit selection of the stem/progenitor cell-like population from human myometrium
formation of CD151 (zeige CD151 Proteine)-integrin complex was likely to be a prerequisite for CD151 (zeige CD151 Proteine)-induced angiogenesis and signaling pathways
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
integrin, alpha 6
, integrin alpha 6 subunit
, integrin alpha chain, alpha 6
, integrin alpha-6
, integrin alpha 6
, integrin alpha-6-like
, CD49 antigen-like family member F
, integrin alpha6B