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Phosphodiesterase 4B Proteine (PDE4B)

Bezeichnung:
Phosphodiesterase 4B Proteine (PDE4B)
Auf www.antikoerper-online.de finden Sie aktuell 4 Phosphodiesterase 4B (PDE4B) Proteine von 1 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Phosphodiesterase 4B Antikörper (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 31 Phosphodiesterase 4B Produkte verfügbar.
Synonyme:
Dpde4, dunce, fj87g04, PDE4/IVb, pde4b, Pde4B1, Pde4B2, Pde4B3, Pde4B4, R74983, wu:fj87g04
alle Proteine anzeigen Gen GeneID UniProt
PDE4B 18578  
PDE4B 24626 P14646
PDE4B    

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Mouse (Murine) Phosphodiesterase 4B (PDE4B) Interaktionspartner

  1. These results demonstrate that the alcohol- induced increase in hepatic Pde4 (zeige PDE4A Proteine), specifically Pde4b expression, and compromised cAMP signalling predispose the liver to impaired fatty acid oxidation and the development of steatosis.

  2. PDE4B phosphorylated by AMPK (zeige PRKAA1 Proteine) at Ser304 is important for activation.

  3. Lymphomas developing in a Pde4b-null background display significantly lower microvessel density in association with lower VEGF (zeige VEGFA Proteine) levels and PI3K/AKT (zeige AKT1 Proteine) activity.

  4. Genetic variations in DISC1 influence formation of biochemical complex with PDE4 and GSK-3 and strengthen the possibility of synergistic interactions between these proteins.

  5. PDE4B-deficient mice display impaired reversal learning in the Morris water maze compared to wild-type littermates.

  6. Results identify PDE4B in the CaV1.2 (zeige CACNA1C Proteine) complex as a critical regulator of ICa during beta-AR stimulation and suggest that distinct PDE4 (zeige PDE4A Proteine) subtypes are important for normal regulation of calcium-induced calcium release in cardiomyocytes.

  7. Findings demonstrate that PDE4D (zeige PDE4D Proteine) and PDE4B have specialized functions in mouse embryonic fibroblasts with PDE4B controlling cAMP in a discrete subdomain near the plasma membrane.

  8. induction is esssential for LPS (zeige TLR4 Proteine)-activated tnf-alpha (zeige TNF Proteine) responses

  9. PDE4B mediates the antipsychotic effects of rolipram in conditioned avoidance responding; the PDE4B-regulated cyclic adenosine monophosphate signaling pathway may play a role in the pathophysiology and pharmacotherapy of psychosis

  10. the PDE4B subfamily is involved in signaling pathways that contribute to anxiogenic-like effects on behavior.

Phosphodiesterase 4B (PDE4B) Protein Überblick

Protein Überblick

contains four isoforms expressed from the same gene\; isoform Pde4b4 has cAMP specific phosphdiesterase activity and is inhibited by rolipram

Alternative names and synonyms associated with Phosphodiesterase 4B (PDE4B)

  • phosphodiesterase 4B, cAMP-specific a (pde4ba)
  • phosphodiesterase 4B, cAMP specific (Pde4b)
  • Dpde4 Protein
  • dunce Protein
  • fj87g04 Protein
  • PDE4/IVb Protein
  • pde4b Protein
  • Pde4B1 Protein
  • Pde4B2 Protein
  • Pde4B3 Protein
  • Pde4B4 Protein
  • R74983 Protein
  • wu:fj87g04 Protein

Bezeichner auf Proteinebene für Phosphodiesterase 4B Proteine (PDE4B)

phosphodiesterase 4B, cAMP-specific a , phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) , phosphodiesterase 4B , 3',5'-cyclic AMP phosphodiesterase , DPDE4 , Phosphodiesterase 4B cAMP-specific (dunce , Phosphodiesterase 4B, cAMP-specific (dunce , cAMP-specific 3',5'-cyclic phosphodiesterase 4B

GENE ID SPEZIES
337624 Danio rerio
18578 Mus musculus
24626 Rattus norvegicus
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