Fibronectin Proteine (FN1)

Fibronectin 1 Proteine (FN1)
Auf finden Sie aktuell 18 Fibronectin 1 (FN1) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Fibronectin Antikörper (194) und Fibronectin Kits (23) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 240 Fibronectin Produkte verfügbar.
CIG, E330027I09, ED-B, fb80d10, FIBNEC, fibronectin, FINC, Fn, fn-1, FN1, fn2, FNZ, GFND, GFND2, LETS, MSF, wu:fb80d10
alle Proteine anzeigen Gen GeneID UniProt
FN1 2335 P02751
FN1 14268 P11276
Ratte FN1 FN1 25661  

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Am meisten referenzierte Fibronectin Proteine

  1. Human Fibronectin Protein expressed in Human Cells - ABIN2002555 : Liu, Fedorov, Pollard, Lattman, Almo, Magnus: Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii. in Journal of structural biology 1998 (PubMed)
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Weitere Proteine zu Fibronectin Interaktionspartnern

Zebrafish Fibronectin 1 (FN1) Interaktionspartner

  1. Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.

  2. Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage

  3. Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.

  4. Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.

  5. reduction of fn1 function enables rescue of cardiac fusion in hand2 (zeige HAND2 Proteine) mutants

  6. Fibronectin regulates epithelial organization during myocardial migration in zebrafish.

Human Fibronectin 1 (FN1) Interaktionspartner

  1. Fibronectin and Hepatocyte Growth Factor (zeige HGF Proteine) were shown to be produced by lung fibroblasts and, furthermore, to enhance malignant pleural mesothelioma cell migration and invasion

  2. Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1 (zeige WWC1 Proteine)), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3 (zeige CELSR3 Proteine)), NIPBL (zeige NIPBL Proteine) (Nipped (zeige RPL38 Proteine)-B-like), and FN1 (fibronectin 1).

  3. fibrillar fibronectin on this polymer, but not a globular conformation obtained on control polymers, promotes synergistic presentation of integrin-binding sites and bound bone morphogenetic protein 2 (BMP-2 (zeige BMP2 Proteine)), which enhances mesenchymal stem cell osteogenesis in vitro and drives full regeneration of a nonhealing bone defect in vivo at low GF concentrations.

  4. Fn plays a critical role in inflammasome-activated cells by amplifying caspase-1 (zeige CASP1 Proteine) activation and inducing inflammatory cell death.

  5. If the expression of Capon (zeige NOS1AP Proteine) is decreased, myeloma cells are adhered to fibronectin or bone marrow stromal cells (bone marrow mesenchymal stem cells). In addition, the sensitivity of the cell line to chemotherapeutic agents was reduced after silencing Capon (zeige NOS1AP Proteine) in the myeloma cell line which was adhered to bone marrow mesenchymal stem cells.

  6. C-terminal truncation of transglutaminase 2 (TG2 (zeige TGM2 Proteine)) reduces binding to the small intestinal extracellular matrix (ECM (zeige MMRN1 Proteine)) despite retained fibronectin (FN)-binding capacity.

  7. analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation

  8. In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (zeige ANGPT2 Proteine) Ang-1 (zeige ANGPT1 Proteine), but not the receptor binding domain of Ang-2 (zeige ANGPT2 Proteine), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (zeige MAPK1 Proteine) signaling in the presence of both Ang-1 (zeige ANGPT1 Proteine) and fibronectin

  9. Results directly implicate the heparin-binding sequence of the first type III repeat of fibrillar fibronectin (FNIII1) in realignment of stress fibers in HUVECs and, importantly, show that the matricryptic heparin-binding RWRPK sequence located in FNIII1 is required for the response.

  10. TGFbeta (zeige TGFB1 Proteine) elevated the expression of CamK (zeige CAMK4 Proteine) IIbeta and CamK (zeige CAMK4 Proteine) IIdelta, while siRNA silencing of those two subtypes significantly reduced TGFbeta (zeige TGFB1 Proteine)-mediated expression of collagen A1 and fibronectin 1.

Mouse (Murine) Fibronectin 1 (FN1) Interaktionspartner

  1. fibronectin has a critical role in tissue morphogenesis and the development of tissue heterogeneities

  2. The aged stem cell niche in skeletal muscle contains reduced levels of FN, leading to detrimental consequences for the function and maintenance of muscle stem cells (MuSCs). FN is a preferred adhesion substrate for MuSCs and integrin-mediated signaling via focal adhesion kinase and the p38 MAPK (zeige MAPK14 Proteine) pathway is strongly de-regulated in MuSCs from aged mice because of insufficient attachment to the niche.

  3. analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation

  4. scleraxis was required for TGFbeta-induced fibronectin expression: TGFbeta lost its ability to induce fibronectin expression following scleraxis knockdown.

  5. The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 (zeige LGALS3 Proteine) as opposed to fibronectin.

  6. Thus, similarly to growth factor signaling, fibronectin matrix assembly during early development can be both autocrine and paracrine.

  7. These results suggest that the Rac1 regulation of the FN arrangement is involved in retinoic acid-induced cleft palate.

  8. Fibrillar cellular fibronectin supports platelet adhesion, activation, aggregation and procoagulant activity via the interplay of a series of receptors i.e. integrins alpha5beta1 and alphaIIbbeta3, the GPIb-V-IX complex, GPVI (zeige GP6 Proteine) and Toll-like receptor 4 (zeige TLR4 Proteine).

  9. Fn1 synthesized by the neural crest mediated morphogenesis of the aortic arch artery and differentiation of neural crest cells into vascular smooth muscle cells by regulating Notch (zeige NOTCH1 Proteine) signaling.

  10. A novel mechanism of transcriptional regulation of fibronectin through CREB (zeige CREB1 Proteine).

Cow (Bovine) Fibronectin 1 (FN1) Interaktionspartner

  1. plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.

  2. Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (zeige TGFB1 Proteine) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.

  3. Putative function of fibronectin and its receptor (integrin alpha(5 (zeige ITGA5 Proteine))beta(1)) in male and female gametes during bovine fertilization in vitro.

  4. These results highlight a crucial role for caveolin-1 (zeige CAV1 Proteine) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.

  5. P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn

Horse (Equine) Fibronectin 1 (FN1) Interaktionspartner

  1. The expression of extracellular matrix molecules fibronectin and osteopontin (zeige SPP1 Proteine) in vitreous and retina samples in autoimmune uveitis was investigated.

Pig (Porcine) Fibronectin 1 (FN1) Interaktionspartner

  1. The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.

  2. The relationship between hyaluronan synthesis and levels of versican (zeige Vcan Proteine), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.

  3. fibronectin has a cryptic binding site for tenascin (zeige TNC Proteine)

Fibronectin (FN1) Protein Überblick

Protein Überblick

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Alternative names and synonyms associated with Fibronectin (FN1)

  • fibronectin 1 (FN1)
  • fibronectin 1 (fn1)
  • fibronectin 1 (Fn1)
  • CIG Protein
  • E330027I09 Protein
  • ED-B Protein
  • fb80d10 Protein
  • FIBNEC Protein
  • fibronectin Protein
  • FINC Protein
  • Fn Protein
  • fn-1 Protein
  • FN1 Protein
  • fn2 Protein
  • FNZ Protein
  • GFND Protein
  • GFND2 Protein
  • LETS Protein
  • MSF Protein
  • wu:fb80d10 Protein

Bezeichner auf Proteinebene für Fibronectin 1 Proteine (FN1)

fibronectin 1 , gene C , fibronectin , fn1l , nat , natter , fibronectin-like , cold-insoluble globulin , migration-stimulating factor , FN , cumulus cell-specific fibronectin 1 transcript , embryo-specific fibronectin 1 transcript , fibronectin ED-A- region , fibronectin variable region

459926 Pan troglodytes
595087 Xenopus (Silurana) tropicalis
613269 Macaca mulatta
100005469 Danio rerio
100405983 Callithrix jacchus
100464134 Ailuropoda melanoleuca
100601303 Nomascus leucogenys
2335 Homo sapiens
396133 Gallus gallus
14268 Mus musculus
25661 Rattus norvegicus
280794 Bos taurus
403845 Canis lupus familiaris
100034189 Equus caballus
397620 Sus scrofa
100732865 Cavia porcellus
100328589 Oryctolagus cuniculus
397744 Xenopus laevis
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