CX3CR1 Proteine (CX3CR1)

Chemokine (C-X3-C Motif) Receptor 1 Proteine (CX3CR1)
Auf finden Sie aktuell 6 Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CX3CR1 Antikörper (193) und CX3CR1 Kits (45) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 256 CX3CR1 Produkte verfügbar.
CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, Rbs11, V28
alle Proteine anzeigen Gen GeneID UniProt
Ratte CX3CR1 CX3CR1 171056 P35411
CX3CR1 1524 P49238
CX3CR1 13051 Q9Z0D9

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Weitere Proteine zu CX3CR1 Interaktionspartnern

Human Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) Interaktionspartner

  1. The fractalkine (zeige CX3CL1 Proteine) functions on the activation of the AKT (zeige AKT1 Proteine)/NF-kappaB (zeige NFKB1 Proteine)/p65 (zeige GORASP1 Proteine) signalling cascade and regulation of the antiapoptosis process in pancreatic cancer cells.

  2. High expression of CX3CR1 correlates with significantly shorter survival, specifically in post-menopausal patients with advanced and terminal stages of the disease. Taken together, this support a key regulatory role for the fractalkine (zeige CX3CL1 Proteine) axis in advanced and relapsed peritoneal metastasis in epithelial ovarian carcinoma.

  3. V249I genotype of the fractalkine receptor showed a protector role in patients with type 2 diabetes. The T280M genotype is associated with increased carotid intima-media thickness in Mexican individuals with or without type 2 diabetes

  4. CX3CR1 genetic variation sows a possible association with hypertension, diabetes mellitus and atherosclerosis comorbidities in patients treated with hemodialysis.

  5. this study shows that the expression of CX3CR1 on tonsillar CD8-positive cells is higher in IgA nephropathy patients

  6. Low CCRL1 expression is associated with hepatocellular carcinoma.

  7. Recent works show that, in allergic diseases, there is an increased expression of fractalkine/CX3CL1 (zeige CX3CL1 Proteine) and its unique receptor CX3CR1 and that this chemokine (zeige CCL1 Proteine) does not act as chemoattractant. In allergic asthma, CX3CR1 expression regulates Th2 and Th1 (zeige TH1L Proteine) cell survival in the inflammatory lung, while, in atopic dermatitis, it regulate Th2 and Th1 (zeige TH1L Proteine) cell retention into the inflammatory site. [review]

  8. CX3CR1 is expressed in the normal, cancer adjacent normal, inflammatory, and malignant fallopian epithelium.

  9. CX3CR1 T allele of rs3732379 might have a positive association with the susceptibility of age-related macular degeneration

  10. CX3CR1 is expressed differentially in human monocytes during differentiation.

Mouse (Murine) Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) Interaktionspartner

  1. Results establish an essential role for the receptor CX3CR1 in gut (zeige GUSB Proteine) macrophages in resolving inflammation in the intestine, where it helps protects against colitis-associated cancer by regulating HMOX-1 (zeige HMOX1 Proteine) expression.

  2. CX3CR1 significantly contributes to changes in microglia morphology in the proximal peri (zeige POSTN Proteine)-infarct area following transient occlusion of the middle cerebral artery. Morphological alterations suggest a shift in microglia functionality integrated in the inflammatory response after stroke. Results show that CX3CR1 deficiency has no beneficial effect on lesion size neither it affects early functional outcome after stroke.

  3. we demonstrated that CX3CR1(Lo)CCR2 (zeige CCR2 Proteine)(Hi) monocytes were recruited to the GBM, where they transitioned to CX3CR1(Hi)CCR2 (zeige CCR2 Proteine)(Lo) macrophages and CX3CR1(Hi)CCR2 (zeige CCR2 Proteine)(-) microglia-like cells. Infiltrating macrophages/monocytes constituted approximately 85% of the total TAM (zeige CCNA1 Proteine) population, with resident microglia accounting for the approximately 15% remaining.

  4. CXCR4 (zeige CXCR4 Proteine), CCR2 (zeige CCR2 Proteine), and CX3CR1 direct dendritic cell precursors from the bone marrow to the lung differentially.

  5. Published data show that genetic deletion of CX3CR1, a microglia-specific chemokine receptor (zeige CCR1 Proteine), promotes recovery after traumatic spinal cord injury in mice, a benefit achieved in part by reducing macrophage-mediated injury at the lesion epicenter. Data in the current manuscript indicate that CX3CR1 deletion changes microglia and macrophage function, creating a tissue microenvironment that enhances endogenous repair.

  6. this reduction in lesion formation was associated with reduced numbers of lesional SMCs but not macrophages within the transplanted Cx3cr-/- Apoe (zeige APOE Proteine)-/- aortic segment. No differences in frequencies of proliferating and apoptotic cells could be observed. These results indicate that CX3CR1 on resident vessel wall cells plays a key role in atherosclerotic plaque formation in transplanted aortic grafts

  7. the individual and combined actions of CCL2 (zeige CCL2 Proteine)/CCR2 (zeige CCR2 Proteine) and CX3CL1 (zeige CX3CL1 Proteine)/CX3CR1 in hypoxia-induced pulmonary hypertension in mice, is reported.

  8. Knockdown of the fractalkine receptor CX3CR1 in embryonic cortical precursors, or constitutive knockout of CX3CR1, causes decreased numbers of oligodendrocyte progenitor cells (OPCs) and oligodendrocytes in the postnatal cortex.

  9. Gas6 (zeige GAS6 Proteine) specifically promotes the recruitment of inflammatory CCR2 (zeige CCR2 Proteine)(hi)CX3CR1(lo) monocytes through the regulation of both CCR2 (zeige CCR2 Proteine) and CCL2 (zeige CCL2 Proteine) during deep venous thrombosis.

  10. Fractalkine (zeige CX3CL1 Proteine)-CX3CR1 signaling has been shown to protect neurons.

CX3CR1 Protein Überblick

Protein Überblick

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with CX3CR1

  • chemokine (C-X3-C motif) receptor 1 (CX3CR1)
  • chemokine (C-C motif) receptor-like 1 (CCRL1)
  • CX3C chemokine receptor 1-like (LOC100028655)
  • CX3C chemokine receptor 1-like (LOC100391413)
  • CX3C chemokine receptor 1-like (LOC100453042)
  • CX3C chemokine receptor 1-like (LOC100481132)
  • CX3C chemokine receptor 1-like (LOC100544445)
  • CX3C chemokine receptor 1-like (LOC100559882)
  • CX3C chemokine receptor 1-like (LOC100622126)
  • CX3C chemokine receptor 1-like (LOC100622491)
  • chemokine (C-X-C motif) receptor 1 (Cxcr1)
  • chemokine (C-X3-C motif) receptor 1 (Cx3cr1)
  • chemokine (C-X3-C) receptor 1 (Cx3cr1)
  • CCRL1 Protein
  • CMKBRL1 Protein
  • CMKDR1 Protein
  • GPR13 Protein
  • GPRV28 Protein
  • Rbs11 Protein
  • V28 Protein

Bezeichner auf Proteinebene für CX3CR1

CX3C chemokine receptor 1 , chemokine (C-C motif) receptor-like 1 , CX3C chemokine receptor 1-like , c-C chemokine receptor type 11-like , chemokine (C-X3-C motif) receptor 1 , C-X-C chemokine receptor type 1 , chemokine receptor CXCR1 , C-X3-C CKR-1 , chemokine (C-X3-C) receptor 1 , fractalkine receptor , CMK-BRL-1 , CMK-BRL1 , G protein-coupled receptor 13 , G-protein coupled receptor 13 , beta chemokine receptor-like 1 , chemokine (C-C) receptor-like 1 , Fractalkine receptor , chemokine receptor 1

460281 Pan troglodytes
693926 Macaca mulatta
470928 Pan troglodytes
608898 Canis lupus familiaris
717701 Macaca mulatta
100028655 Monodelphis domestica
100391413 Callithrix jacchus
100440536 Pongo abelii
100453042 Pongo abelii
100481132 Ailuropoda melanoleuca
100544445 Meleagris gallopavo
100559882 Anolis carolinensis
100604041 Nomascus leucogenys
100622126 Sus scrofa
100622491 Sus scrofa
100379619 Cavia porcellus
171056 Rattus norvegicus
1524 Homo sapiens
485599 Canis lupus familiaris
100124525 Bos taurus
100008874 Oryctolagus cuniculus
100735615 Cavia porcellus
420719 Gallus gallus
101113016 Ovis aries
13051 Mus musculus
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