CCL5 Proteine (CCL5)

Chemokine (C-C Motif) Ligand 5 Proteine (CCL5)
Auf finden Sie aktuell 119 Chemokine (C-C Motif) Ligand 5 (CCL5) Proteine von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CCL5 Antikörper (315) und CCL5 Kits (118) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 562 CCL5 Produkte verfügbar.
D17S136E, eoCP, MuRantes, RANTES, SCYA5, SIS-delta, SISd, TCP228
alle Proteine anzeigen Gen GeneID UniProt
CCL5 81780  
CCL5 6352 P13501
CCL5 20304 P30882

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Am meisten referenzierte CCL5 Proteine

  1. Human CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666976 : Cocchi, DeVico, Garzino-Demo, Arya, Gallo, Lusso: Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. in Science (New York, N.Y.) 1996 (PubMed)
    Zeige alle 9 Referenzen für 2666976

  2. Mouse (Murine) CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666879 : Schall, Bacon, Toy, Goeddel: Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. in Nature 1990 (PubMed)
    Zeige alle 6 Referenzen für 2666879

  3. Human CCL5 Protein expressed in Human Cells - ABIN2003576 : Maghazachi, Al-Aoukaty, Schall: CC chemokines induce the generation of killer cells from CD56+ cells. in European journal of immunology 1996 (PubMed)
    Zeige alle 5 Referenzen für 2003576

  4. Human CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666697 : Larrubia, Benito-Martínez, Calvino, Sanz-de-Villalobos, Parra-Cid: Role of chemokines and their receptors in viral persistence and liver damage during chronic hepatitis C virus infection. in World journal of gastroenterology : WJG 2008 (PubMed)
    Zeige alle 5 Referenzen für 2666697

  5. Human CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN1046691 : Schall, Jongstra, Dyer, Jorgensen, Clayberger, Davis, Krensky: A human T cell-specific molecule is a member of a new gene family. in Journal of immunology (Baltimore, Md. : 1950) 1988 (PubMed)
    Zeige alle 2 Referenzen für 1046691

Weitere Proteine zu CCL5 Interaktionspartnern

Human Chemokine (C-C Motif) Ligand 5 (CCL5) Interaktionspartner

  1. Cancer-FOXP3 serves as a prognostic biomarker and a crucial determinant of immunosuppressive microenvironment via recruiting Treg cells by directly trans-activating CCL5. Therefore, cancer-FOXP3 could be used to select patients with better response to CCL5/CCR5 blockade immunotherapy.

  2. data suggest that STAT2 (zeige STAT2 Proteine) plays a role in the psoriasis pathogenesis by regulating the expression of CXCL11 (zeige CXCL11 Proteine) and CCL5, and thereby attracting IFNgamma-producing immune cells to the skin

  3. Mean RANTES concentrations in nasal fluid in patients with perennial allergic rhinitis and nonallergic and allergic chronic rhinosinusitis with nasal polyps patients were significantly higher in comparison to control subjects.

  4. All fatty necrotic and osteolytic jawbone (FDOJ) samples showed high expression of RANTES and fibroblast growth factor (FGF)-2 (zeige FGF2 Proteine).

  5. This study showed that RANTES is important in the regulation of vascular dysfunction through modulation of perivascular inflammation.

  6. These data indicate that ECFCs, not SPCs, are the major players in MMD (zeige MMD Proteine) pathogenesis and that the chemokine (zeige CCL1 Proteine) CCL5 mediates the interactions. It can be hypothesized that in MMD (zeige MMD Proteine) patients, defective ECFCs direct aberrant SPC (zeige UCN3 Proteine) recruitment to critical vascular locations through the action of CCL5.

  7. miR (zeige MLXIP Proteine)-200c represses IL-6 (zeige IL6 Proteine), IL-8 (zeige IL8 Proteine) and CCL-5 and improves osteogenic differentiation

  8. this study shows that melanoma peptides vaccination and intratumoral administration of IFNgamma increases production of CCL5 in patient tumors

  9. Findings indicate the importance of chemokine (CC motif) ligand 5 (CCL5) genetic variability and CCL5-CCR5 (CC chemokine receptor 5) axis on the susceptibility to HCV.

  10. combined experimentally determined binding affinities (KD) of several orthologs of CCL5 with HNP1 (zeige DEFA1 Proteine) with in silico studies to identify the most likely heterodimeric CCL5-HNP1 (zeige DEFA1 Proteine) complex which was subsequently used as a starting structure to rationally design peptidic inhibitors

Mouse (Murine) Chemokine (C-C Motif) Ligand 5 (CCL5) Interaktionspartner

  1. A robust up-regulation of RANTES within the brain was seen in a mouse model of tick-borne encephalitis.

  2. CCL5 paradoxically limits macrophage accumulation in the injured kidney during renin (zeige REN Proteine) angiotensin system (RAS) activation by constraining the proinflammatory actions of CCL2 (zeige CCL2 Proteine).

  3. This study showed that RANTES is important in the regulation of vascular dysfunction through modulation of perivascular inflammation.

  4. IL-6 (zeige IL6 Proteine) Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2 (zeige CCL2 Proteine)/CCL5 in Non-small Cell Lung Cancer

  5. Blocking antibodies against RANTES and eotaxin reduced the infiltration of CD4 (zeige CD4 Proteine)(+) and CD8 (zeige CD8A Proteine)(+) T cells into the nigra, attenuated nigral expression of proinflammatory molecules, and suppressed nigral activation of glial cells. These findings paralleled dopaminergic neuronal protection, normalized striatal neurotransmitters, and improved motor functions in MPTP (zeige PTPN2 Proteine)-intoxicated mice.

  6. CCL5 deficiency resulted in reduced neointima formation after carotid artery injury and thrombosis.

  7. RANTES produced by renal tubular cells act as a key chemokine (zeige CCL1 Proteine) in acute kidney injury and HIF-1alpha (zeige HIF1A Proteine) regulated LncRNA-PRINS might be involved in RANTES production.

  8. Mycobacterium chelonae activates the gene expressions of chemokine (C-C motif) ligand 2 (CCL2 (zeige CCL2 Proteine)) and CCL5 in murine bone marrow-derived macrophages and in vivo mouse model.

  9. Neutralization of circulating RANTES decreased liver neutrophilic infiltration

  10. CCL5 signaling through CCR5 may increase platelet counts during physiological stress.

Pig (Porcine) Chemokine (C-C Motif) Ligand 5 (CCL5) Interaktionspartner

  1. These results represent an important molecular mechanism whereby H. parasuis induced RANTES in the inflammatory response.

  2. Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced RANTES transcription.

  3. we cloned the nucleotide sequence of the 5'-flanking region of the porcine RANTES (poRANTES) gene and characterized the regulatory elements that activate transcription

  4. The Toll (zeige TLR4 Proteine)-like receptor signaling pathway is involved in porcine reproductive and respiratory syndrome virus-induced RANTES activation.

  5. These results suggest that porcine RANTES can play an important role in xenotransplant rejection, through participating in the interaction between porcine endothelial cells and human monocytes.

Cow (Bovine) Chemokine (C-C Motif) Ligand 5 (CCL5) Interaktionspartner

  1. CCL5 but not CCL2 (zeige CCL2 Proteine) mainly attract bovine classical monocytes and promote their differentiation into LPS (zeige IRF6 Proteine)-hypo-responsive macrophages.

  2. decrease in sensitivity of HIV variants to RANTES neutralization during the course of progressive infection, but not during follow-up of long term survivors; data suggest a role for RANTES neutralization sensitivity of HIV-1 in AIDS pathogenesis

Guinea Pig Chemokine (C-C Motif) Ligand 5 (CCL5) Interaktionspartner

  1. In the pathogenesis of allergic rhinitis, substance P (zeige TAC1 Proteine) induces expression of RANTES in nasal mucosa.

Rhesus Monkey Chemokine (C-C Motif) Ligand 5 (CCL5) Interaktionspartner

  1. CCL3 (zeige CCL3 Proteine), CCL4 (zeige CCL4 Proteine) and CCL5 gene expression was evaluated in response to simian-human immunodeficiency virus (SHIV) infection in a rhesus macaque model.

CCL5 Protein Überblick

Protein Überblick

This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.

Alternative names and synonyms associated with CCL5

  • chemokine (C-C motif) ligand 5 (LOC100230935)
  • chemokine (C-C motif) ligand 5 (CCL5)
  • chemokine (C-C motif) ligand 5 (Ccl5)
  • D17S136E Protein
  • eoCP Protein
  • MuRantes Protein
  • RANTES Protein
  • SCYA5 Protein
  • SIS-delta Protein
  • SISd Protein
  • TCP228 Protein

Bezeichner auf Proteinebene für CCL5

chemokine (C-C motif) ligand 5 , small inducible cytokine A5 , C-C motif chemokine 5 , SIS-delta , T-cell-specific protein RANTES , regulated upon activation normal T-cell expressed and secreted , small-inducible cytokine A5 , T-cell specific protein p288 , beta-chemokine RANTES , eosinophil chemotactic cytokine , regulated upon activation, normally T-expressed, and presumably secreted , small inducible cytokine subfamily A (Cys-Cys), member 5 , chemokine ah294 , small inducible cytokine A5 RANTES , chemokine CCL5/RANTES , chemokine ligand 5

100230935 Taeniopygia guttata
747004 Pan troglodytes
81780 Rattus norvegicus
6352 Homo sapiens
20304 Mus musculus
417465 Gallus gallus
403522 Canis lupus familiaris
396613 Sus scrofa
327712 Bos taurus
100135495 Cavia porcellus
493689 Felis catus
100033925 Equus caballus
101115553 Ovis aries
574178 Macaca mulatta
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