Plakophilin 4 Proteine (PKP4)

Plakophilin 4 Proteine (PKP4)
Auf finden Sie aktuell 3 Plakophilin 4 (PKP4) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Plakophilin 4 Antikörper (46) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 52 Plakophilin 4 Produkte verfügbar.
5031422I09Rik, 9430019K17Rik, Armrp, CTNND2, MGC146695, p0071, PKP4
alle Proteine anzeigen Gen GeneID UniProt
PKP4 8502 Q99569
PKP4 227937 Q68FH0
Ratte PKP4 PKP4 295625  

Weitere Synonyme anzeigen

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Human Plakophilin 4 (PKP4) Interaktionspartner

  1. p0071 has a key role in regulating recycling through the Rab11a (zeige RAB11A Proteine)-dependent perinuclear recycling compartment.

  2. This review article focuses on the functions of the p0071 protein and its closest relatives in regulating cell adhesion and cytoskeletal organization, which are critically involved in the control of cell polarity. [review]

  3. Findings suggest that aspects of folliculin (zeige FLCN Proteine) tumour suppressor function are linked to interaction with p0071 and the regulation of RhoA (zeige RHOA Proteine) signalling.

  4. These data support a model in which dysregulation of the FLCN (zeige FLCN Proteine)-p0071 interaction leads to alterations in cell adhesion, cell polarity, and RhoA (zeige RHOA Proteine) signaling.

  5. The structural and functional roles of p0071 are suggested by its preferential occurrence in distinct tubule segments, and its potential use as a cytodiagnostic cell type marker in renal pathology is discussed.

  6. ERBIN (zeige ERBB2IP Proteine) interacts in vivo with p0071 and that it may be involved in the organization of adherens junctions and the desmosomes of epithelia

  7. In addition to plakoglobin (zeige JUP Proteine), p0071 is the second armadillo (zeige PKP1 Proteine) protein present in both types of adhesive junctions and may play a role in regulating crosstalk between adherens junctions and desmosomes.

  8. p0071 bound to the first 160 amino-terminal residues of desmoplakin and also interacted directly with plakoglobin (zeige JUP Proteine), suggesting that p0071 may regulate desmosome assembly by controlling plakoglobin (zeige JUP Proteine) availability

  9. These findings support an essential role for p0071 in spatially regulating restricted Rho signalling during cytokinesis.

  10. In this review p0071 catenin, a close relative of p120 catenin (zeige CTNND1 Proteine), associates and regulates RhoA-GTPase at the cleavage furrow during cytokinesis.

Mouse (Murine) Plakophilin 4 (PKP4) Interaktionspartner

  1. results identify p0071 as an important and novel FMRP (zeige FMR1 Proteine) target and strongly suggest that impaired actin cytoskeletal functions mediated by an excess of p0071 are key aspects underlying the fragile X (zeige FMR1 Proteine) syndrome

  2. These data support a model in which dysregulation of the FLCN (zeige FLCN Proteine)-p0071 interaction leads to alterations in cell adhesion, cell polarity, and RhoA (zeige RHOA Proteine) signaling.

Plakophilin 4 (PKP4) Protein Überblick

Protein Überblick

Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants have been found for this gene, but the full-length nature of only two of them have been described so far. These two variants encode distinct isoforms.

Alternative names and synonyms associated with Plakophilin 4 (PKP4)

  • plakophilin 4 (PKP4)
  • plakophilin 4 (pkp4)
  • plakophilin 4 (Pkp4)
  • 5031422I09Rik Protein
  • 9430019K17Rik Protein
  • Armrp Protein
  • CTNND2 Protein
  • MGC146695 Protein
  • p0071 Protein
  • PKP4 Protein

Bezeichner auf Proteinebene für Plakophilin 4 Proteine (PKP4)

plakophilin 4 , catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) , catenin 4 , plakophilin-4 , armadillo-related protein

424328 Gallus gallus
459676 Pan troglodytes
478759 Canis lupus familiaris
527732 Bos taurus
780351 Xenopus (Silurana) tropicalis
100050975 Equus caballus
100546711 Meleagris gallopavo
100561325 Anolis carolinensis
8502 Homo sapiens
281406 Bos taurus
227937 Mus musculus
295625 Rattus norvegicus
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