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Integrin beta 1 Proteine (ITGB1)

Bezeichnung:
Integrin beta 1 Proteine (ITGB1)
Auf www.antikoerper-online.de finden Sie aktuell 19 Integrin beta 1 (ITGB1) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Integrin beta 1 Antikörper (854) und Integrin beta 1 Kits (38) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 925 Integrin beta 1 Produkte verfügbar.
Synonyme:
4633401G24Rik, AA409975, AA960159, CD29, ENSMUSG00000051907, FNRB, Gm9863, GPIIA, itgb1, MDF2, MSK12, VLA-BETA, VLAB
alle Proteine anzeigen Gen GeneID UniProt
ITGB1 16412 P09055
ITGB1 24511 P49134
ITGB1 3688 P05556

Weitere Synonyme anzeigen

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Am meisten referenzierte Integrin beta 1 Proteine

  1. Human ITGB1 Protein expressed in Wheat germ - ABIN2752830 : Ahn, Mohamedali, Anand, Cheruku, Birch, Sowmya, Cantor, Ranganathan, Inglis, Frank, Agrez, Nice, Baker: Characterization of the interaction between heterodimeric ?v?6 integrin and urokinase plasminogen activator receptor (uPAR) using functional proteomics. in Journal of proteome research 2014 (PubMed)

Weitere Proteine zu Integrin beta 1 Interaktionspartnern

Xenopus laevis Integrin beta 1 (ITGB1) Interaktionspartner

  1. Findings demonstrate the neurotrophin (zeige BDNF Proteine), BDNF (zeige BDNF Proteine)-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (zeige MAG Proteine) .

  2. Findings identify beta(1)-integrin as an important functional cargo during Ca(2+)-dependent rapid endocytosis stimulated by a diffusible guidance cue in Xenopus spinal neurons.

Mouse (Murine) Integrin beta 1 (ITGB1) Interaktionspartner

  1. FAK sustained the active integrin conformation by maintaining talin association with Rab11 endosomes in a type I phosphatidylinositol phosphate kinase (PIPKIgamma)-dependent manner.

  2. results demonstrate that c-Cbl (zeige CBL Proteine) mediates the ubiquitination/degradation of integrin beta1, which leads to COMP (zeige COMP Proteine) deficiency-induced dilated cardiomyopathy.

  3. Ptrh2 (zeige PTRH2 Proteine) levels were up-regulated in dystrophin (zeige DMD Proteine) deficient mdx (zeige DMD Proteine) muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx (zeige DMD Proteine) muscle and Duchenne muscular dystrophy (zeige DMD Proteine) patients. Similar to the a7 integrin, Ptrh2 (zeige PTRH2 Proteine) expression was decreased in laminin-a2 null gastrocnemius muscle

  4. this study has identified a new role for Parvin (zeige PARVA Proteine) and alphaPix (zeige ARHGEF6 Proteine) downstream of the integrin-ILK (zeige ILK Proteine) signaling axis for mammary epithelial cell differentiation.

  5. low expression of alpha2beta1 integrin increased protein kinase B (AKT) activation and alpha-smooth muscle actin (alpha-SMA) expression. This occurred due to the instability of phosphatase and tensin homolog (PTEN) in myofibroblasts on fibrillar collagen.

  6. By modulating its affinity with kindlin, beta3 integrin (zeige ITGB3 Proteine) may be able to locate near the cell edge where it can control beta1 integrin activation and clustering.

  7. These findings indicated that mechanical strain promoted osteoblastic differentiation through integrinbeta1mediated beta-catenin (zeige CTNNB1 Proteine) signaling.

  8. TERT (zeige TERT Proteine) may promote gastric cancer metastasis through the TERT (zeige TERT Proteine)-miR (zeige MLXIP Proteine)-29a-ITGB1 regulatory pathway.

  9. the rate of collagen I degradation was increased in Poldip2 (zeige POLDIP2 Proteine)(+/-) vs. Poldip2 (zeige POLDIP2 Proteine)(+/+) MASMs. Conversely, activation of the PI3K/Akt (zeige AKT1 Proteine)/mTOR (zeige FRAP1 Proteine) signaling pathway, involved in regulation of protein synthesis, was significantly elevated in Poldip2 (zeige POLDIP2 Proteine)(+/-) MASMs as was beta1-integrin expression.

  10. These findings show that talin and kindlin cooperatively activate integrins leading to fibronectin (zeige FN1 Proteine) binding and adhesion.

Human Integrin beta 1 (ITGB1) Interaktionspartner

  1. SHANK1 and SHANK3 act as integrin activation inhibitors by sequestering active Rap1 (zeige RABGEF1 Proteine) and R-Ras via the SPN (zeige SPN Proteine) domain and thus limiting their bioavailability at the plasma membrane.

  2. nuclear-cytoplasmic shuttling of ICAP1 (zeige ITGB1BP1 Proteine) influences both integrin activation and KRIT1 (zeige KRIT1 Proteine) localization, presumably impacting nuclear functions of KRIT1 (zeige KRIT1 Proteine).

  3. The main significance of this work is the discovery of EPO (zeige EPO Proteine) as a novel ligand for the HER2 (zeige ERBB2 Proteine) receptor. Following HER2 (zeige ERBB2 Proteine) activation, EPO (zeige EPO Proteine) induces activation of FAK (zeige PTK2 Proteine) and subsequent activation of beta1-integrin, via inside-out signaling. This complex results in downstream activation of ERK1/2 and a sustained up regulation of both MUC4 (zeige MUC4 Proteine) and the HER2 (zeige ERBB2 Proteine) receptor

  4. we observed that PRL-3 regulated the clustering of integrin beta1 in FAs (zeige FAS Proteine) on collagen I but not on fibronectin (zeige FN1 Proteine). This work identifies PRL-3 as a new regulator of cell adhesion structures to the extracellular matrix, and further supports PRL-3 as a key actor of metastasis in uveal melanoma, of which molecular mechanisms are still poorly understood

  5. Study demonstrates that MARVELD1 (zeige MARVELD1 Proteine)-mediated balance of integrin beta1 and beta4 regulates cell surface ultrastructure and epithelial-mesenchymal transition phenotype of non-small cell lung cancer (NSCLC).

  6. Expression levels of CD98 (zeige SLC3A2 Proteine) and beta1-integrin-A (the activated form of beta1-integrin) were significantly increased in hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) tissues relative to those of normal liver tissues.

  7. High expression of ITGB1 is associated with migration and invasion of nonsmall cell lung cancer.

  8. Our results suggest that an impairment in adhesion exists in vitiligo (zeige MITF Proteine) skin, which is supported by the diminished immunohistochemical expression of laminin, beta1 integrin, ICAM-1 (zeige ICAM1 Proteine) and VCAM-1 (zeige VCAM1 Proteine).

  9. The altered expression of anti-apoptotic gene Bcl-2 (zeige BCL2 Proteine) played critical roles in regulating both spontaneous and radiation-induced apoptosis in the presence of RelB (zeige RELB Proteine) knockdown. For the first time, we showed that RelB (zeige RELB Proteine) knockdown significantly attenuated the migration and invasion of DU145 prostate cancer cells, due to the reduction of integrin b-1

  10. ITGB1 role in hepatocellular carcinoma cell adhesion and motility

Pig (Porcine) Integrin beta 1 (ITGB1) Interaktionspartner

  1. beta1-integrin antigen-antibody interactions and the distribution of beta1-integrin protein on spermatogonial stem cell membrane were demonstrated using atomic force microscopy

Cow (Bovine) Integrin beta 1 (ITGB1) Interaktionspartner

  1. The overall findings suggest that the secreted galectin-3 (zeige LGALS3 Proteine) stimulated by PGF (zeige PGF Proteine) plays a role in structural luteolysis by binding to beta 1 integrin.

  2. Putative function of fibronectin (zeige FN1 Proteine) and its receptor (integrin alpha(5 (zeige ITGA5 Proteine))beta(1)) in male and female gametes during bovine fertilization in vitro.

  3. integrin activation with shear stress results in SFK-regulated caveolin-1 phosphorylation that, in turn, mediates Csk association at integrin sites, where it plays a role in downstream, shear-stimulated myosin light chain diphosphorylation.

  4. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  5. both the gpIb-VWF (zeige VWF Proteine) interaction and the integrin alpha(2 (zeige ITGA2 Proteine))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (zeige GSTA3 Proteine))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (zeige VWF Proteine) is bound

  6. TRPV4 (zeige TRPV4 Proteine) channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.

Integrin beta 1 (ITGB1) Protein Überblick

Protein Überblick

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with Integrin beta 1 (ITGB1)

  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (itgb1-b)
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (ITGB1)
  • integrin beta 1 (fibronectin receptor beta) (Itgb1)
  • integrin, beta 1 (Itgb1)
  • 4633401G24Rik Protein
  • AA409975 Protein
  • AA960159 Protein
  • CD29 Protein
  • ENSMUSG00000051907 Protein
  • FNRB Protein
  • Gm9863 Protein
  • GPIIA Protein
  • itgb1 Protein
  • MDF2 Protein
  • MSK12 Protein
  • VLA-BETA Protein
  • VLAB Protein

Bezeichner auf Proteinebene für Integrin beta 1 Proteine (ITGB1)

integrin beta 1 , integrin beta-1* , integrin beta-1-B , VLA-4 subunit beta , fibronectin receptor subunit beta , integrin beta-1 , beta OL , beta oligodendroglia , integrin VLA-4 subunit beta , integrin beta 1 (fibronectin receptor beta) , glycoprotein IIa , integrin VLA-4 beta subunit , very late activation protein, beta polypeptide , integrin beta-1 subunit , CSAT antigen , JG22 antigen , RGD-receptor , Fibronectin receptor subunit beta , Integrin VLA-4 subunit beta , Integrin subunit beta-1

GENE ID SPEZIES
399443 Xenopus laevis
574312 Macaca mulatta
100055024 Equus caballus
16412 Mus musculus
24511 Rattus norvegicus
3688 Homo sapiens
397019 Sus scrofa
751821 Felis catus
374058 Gallus gallus
477956 Canis lupus familiaris
281876 Bos taurus
443141 Ovis aries
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