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anti-Human Claudin 1 Antikörper:
anti-Mouse (Murine) Claudin 1 Antikörper:
anti-Rat (Rattus) Claudin 1 Antikörper:
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Human Monoclonal Claudin 1 Primary Antibody für IHC (p), IP - ABIN563931
Mee, Grove, Harris, Hu, Balfe, McKeating: Effect of cell polarization on hepatitis C virus entry. in Journal of virology 2007
Show all 16 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody für WB - ABIN2801934
Halford, Spencer, Greenwood, Winton, Hunt, Adamson: Assignment of claudin-1 (CLDN1) to human chromosome 3q28-->q29 with somatic cell hybrids. in Cytogenetics and cell genetics 2000
Show all 4 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody für ELISA, ICC - ABIN4298947
Dietze, Shihan, Stammler, Konrad, Scheiner-Bobis: Cardiotonic steroid ouabain stimulates expression of blood-testis barrier proteins claudin-1 and -11 and formation of tight junctions in Sertoli cells. in Molecular and cellular endocrinology 2015
Show all 2 Pubmed References
Human Monoclonal Claudin 1 Primary Antibody für CyTOF, FACS - ABIN4898991
Farquhar, Hu, Harris, Davis, Brimacombe, Fletcher, Baumert, Rappoport, Balfe, McKeating: Hepatitis C virus induces CD81 and claudin-1 endocytosis. in Journal of virology 2012
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Cow (Bovine) Polyclonal Claudin 1 Primary Antibody für IHC, WB - ABIN2778045
Coyne, Gambling, Boucher, Carson, Johnson: Role of claudin interactions in airway tight junctional permeability. in American journal of physiology. Lung cellular and molecular physiology 2003
Human Polyclonal Claudin 1 Primary Antibody für IF (p), IHC (p) - ABIN686407
Wang, Chen, Liang, Yan, Lin, Liu, Luo, Huang, Li, Liu, Tang: Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?. in Cell and tissue research 2014
Human Monoclonal Claudin 1 Primary Antibody für FACS - ABIN4895295
Giugliano, Petroff, Warren, Jasti, Linscheid, Ward, Kramer, Dobrinskikh, Sheiko, Gale, Golden-Mason, Winn, Rosen: Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. in Journal of immunology (Baltimore, Md. : 1950) 2015
Tumor necrosis factor-alpha (zeige TNF Antikörper) increases claudin-1, 4, and 7 expression in renal tubular cells, altering permeability and transepithelial electrical resistance.
Cyclosporine A/sirolimus alter claudin-1 expression in renal proximal tubular cells via ERK1/2 (zeige MAPK1/3 Antikörper) signaling pathway to alter barrier function.
Data show that miR-30a could bind to the 3'-untranslted region of Slug mRNA and increased expression of claudins, a family of tight junction transmembrane proteins.
These findings indicate a previously unrecognized mechanism that miR (zeige MLXIP Antikörper)-142-5p, targeting CLDN1, plays an important role in Hashimoto's thyroiditis pathogenesis.
Here, the authors identified an interaction between claudin-1 (zeige CLDN7 Antikörper) and Sec24C (zeige SEC24C Antikörper), a cargo-sorting component of the coat protein (zeige GOLPH3 Antikörper) complex II (COPII) vesicular transport system.
Aberrant expression of the tight junction molecules claudin-1 (zeige CLDN7 Antikörper) and zonula occludens-1 (zeige TJP1 Antikörper) mediates cell growth and invasion in oral squamous cell carcinoma cells.
Increased expression of intestinal epithelial claudin-1 (zeige CLDN7 Antikörper) with downregulation of claudin-3 (zeige CLDN3 Antikörper) has been observed in intestinal inflammatory disorders.
Studies indicate claudin 1 (CLDN-1) as a target for improving epidermal drug absorption and preventing HCV infection and of claudin 4 (CLDN-4 (zeige CLDN4 Antikörper)) as a target for anticancer therapeutics.
Data show that the charge of Lys65 in claudin 1 (Cldn1) and Glu158 in claudin 3 (Cldn3 (zeige CLDN3 Antikörper)), and of Gln57 in claudin 5 (Cldn5 (zeige CLDN5 Antikörper)) are necessary for tight junction (TJ) strand formation.
Studies indicate that claudin-1 (zeige CLDN7 Antikörper) accumulate in early endosomes in both epithelial and endothelial cells.
These results revealed that CLDN1 contributed to cancer stem cell features of hepatocellular carcinoma, which was altered by TMPRSS4 (zeige TMPRSS4 Antikörper) expression via ERK1/2 (zeige MAPK1/3 Antikörper) signaling pathway, providing promising targets for novel specific therapies.
Data suggest that epithelial-mesenchymal transition (EMT (zeige ITK Antikörper)) is regulated by ZMYND8 (zeige ZMYND8 Antikörper) (receptor for activated protein kinase C (zeige GNB2L1 Antikörper)) which selectively activates gene promoters of CLDN1 (claudin 1) and CDH1 (E-cadherin (zeige CDH1 Antikörper)) in breast cancer cells; thus, the presence of ZMYND8 (zeige ZMYND8 Antikörper) could be implicated in maintaining epithelial phenotype of cells; ZMYND8 (zeige ZMYND8 Antikörper) regulates invasion/migration of breast cancer cells.
Taken together, these results demonstrate that BTZ (zeige CASC3 Antikörper)-induced claudin 1 expression may be a valuable therapeutic approach for AD.
Results suggest that TLR4 (zeige TLR4 Antikörper)-dependent claudin-1 internalization and secondary anion secretion contribute to irinotecan-induced diarrhea.
The data suggested that miR (zeige MLXIP Antikörper)-29a may regulate tumor growth and migration by targeting CLDN1.
Data show that the spatiotemporal expression of claudin-1 is dysregulated in homeobox (zeige PRRX1 Antikörper) (Msx) genes Msx1d/d/Msx2d/d uteri.
Cldn-1 is a positive regulator of osteoblast proliferation and differentiation.
We further demonstrate that KRT76 interacts with CLDN1 and propose that this interaction is necessary to correctly position CLDN1 in tight junctions.
MIR29 targets and reduces expression of CLDN1 and NKRF (zeige NKRF Antikörper) to increase intestinal permeability in inflammatory bowel disease.
Occludin (zeige OCLN Antikörper) and Claudin-1 expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.
regulates intestinal epithelial homeostasis via regulation of Notch (zeige NOTCH1 Antikörper)-signalling
Downregulation of Sirt1 (zeige SIRT1 Antikörper) and upregulation of the tight junction protein Claudin-1 by SIRT1 (zeige SIRT1 Antikörper)-mediated epigenetic regulation in podocytes contributed to albuminuria.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
, claudin 19
, claudin 1
, senescence-associated epithelial membrane protein 1
, tight junction protein