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Cadherin 5 Proteine (CDH5)

Bezeichnung:
Cadherin 5 Proteine (CDH5)
Auf www.antikoerper-online.de finden Sie aktuell 19 Cadherin 5 (CDH5) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Cadherin 5 Antikörper (335) und Cadherin 5 Kits (65) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 428 Cadherin 5 Produkte verfügbar.
Synonyme:
7B4, AA408225, cadherin-5, CD144, VE-Cad, Vec, VEcad, VECD, wu:fc88a07
alle Proteine anzeigen Gen GeneID UniProt
CDH5 12562 P55284
CDH5 307618  
CDH5 1003 P33151

Weitere Synonyme anzeigen

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Am meisten referenzierte Cadherin 5 Proteine

  1. Mouse (Murine) Cadherin 5 Protein expressed in Human Cells - ABIN2007491 : Angst, Marcozzi, Magee: The cadherin superfamily: diversity in form and function. in Journal of cell science 2001 (PubMed)
    Zeige alle 5 Referenzen für ABIN2007491

  2. Human Cadherin 5 Protein expressed in Human Cells - ABIN2002841 : Duguay, Foty, Steinberg: Cadherin-mediated cell adhesion and tissue segregation: qualitative and quantitative determinants. in Developmental biology 2003 (PubMed)
    Zeige alle 5 Referenzen für ABIN2002841

  3. Rat (Rattus) Cadherin 5 Protein expressed in Human Cells - ABIN2009411 : Bayas, Leung, Evans, Leckband: Lifetime measurements reveal kinetic differences between homophilic cadherin bonds. in Biophysical journal 2006 (PubMed)
    Zeige alle 4 Referenzen für ABIN2009411

Weitere Proteine zu Cadherin 5 Interaktionspartnern

Mouse (Murine) Cadherin 5 (CDH5) Interaktionspartner

  1. Galphas (zeige GNAS Proteine) depletion blocks the S1PR1 (zeige S1PR1 Proteine)-activation induced VE-cadherin stabilization at junctions.

  2. Rab11a/Rab11 (zeige RAB11A Proteine) family-interacting protein 2 (zeige RAB11FIP2 Proteine)-mediated VE-cadherin recycling is required for formation of adherens junctions and restoration of vascular endothelial barrier integrity.

  3. These findings together demonstrate the essential role of KDM4A (zeige KDM4A Proteine) and KDM4C (zeige KDM4C Proteine) in orchestrating mESC differentiation to endothelial cells through the activation of Flk1 (zeige KDR Proteine) and VE-cadherin promoters, respectively

  4. In the absence of Tie-2 (zeige TEK Proteine), VE-PTP (zeige PTPRB Proteine) inhibition destabilizes endothelial barrier integrity in agreement with the VE-cadherin-supportive effect of VE-PTP (zeige PTPRB Proteine).

  5. identification of novel components of the adherens junction complex, and introduction of a novel molecular mechanism through which the VE-cadherin complex controls YAP (zeige YAP1 Proteine) transcriptional activity

  6. Endotoxin challenge initiates interrelated changes in microvessel Cx43 (zeige GJA1 Proteine), VE-cadherin, and microvessel permeability, with changes in Cx43 (zeige GJA1 Proteine) temporally leading the other responses.

  7. Mutating Y731 in the cytoplasmic tail of VE-cadherin, known to selectively affect leukocyte diapedesis, but not the induction of vascular permeability, attenuates bleeding.

  8. mRNA of HIF-2alpha (zeige EPAS1 Proteine) and Ets-1 (zeige ETS1 Proteine) were significantly increased by HIF-3alpha ablation. Both factors activate the VE-cadherin gene, the transcriptional repression of these factors by HIF-3alpha is important for silencing the irrelevant expression of the VE-cadherin

  9. iPS (zeige SLC27A4 Proteine) cell-derived Flk1 (zeige KDR Proteine)(+)VE-cadherin(+) cells expressing the Er71 (zeige ETV2 Proteine) are as angiogenic as mES (zeige PTCH1 Proteine) cell-derived cells and incorporate into CD31 (zeige PECAM1 Proteine)(+) neovessels.

  10. VE-cadherin tyrosine phosphorylation at Y685 is a physiological and hormonally regulated process in female reproductive organs.

Zebrafish Cadherin 5 (CDH5) Interaktionspartner

  1. C1qr (zeige CD93 Proteine) and c1qrl regulate angiogenesis through controlling endothelial cdh5 expression.

  2. the conserved targeting of VE-cadherin by miR (zeige MYLIP Proteine)-22 regulates endothelial inflammation, tissue injury, and angiogenesis.

  3. VE-cadherin/amotL2 (zeige AMOTL2 Proteine) complex is responsible for transmitting mechanical force between endothelial cells for the coordination of cellular morphogenesis consistent with aortic lumen expansion and function.

  4. Cdh5 organizes junctional and cortical actin cytoskeletons and F-actin polymerization during endothelial cell elongation.

  5. Regulatory pathways affecting vascular stabilization via VE-cadherin dynamics

  6. suggest that Ve-cadherin and Moesin1 (zeige MSN Proteine) function to establish and maintain apical/basal polarity during multicellular lumen formation in the intersegmental vessels

  7. results demonstrate a significant role for VE-cadherin in cardiac development independent of its effects on the formation of the peripheral vasculature

  8. fli1 (zeige FLI1 Proteine), and etsrp (zeige ETV2 Proteine), demonstrated that erg (zeige KCNH2 Proteine) and fli1 (zeige FLI1 Proteine) act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin

  9. VE-cadherin plays an essential role in vascular development

Human Cadherin 5 (CDH5) Interaktionspartner

  1. EGFR (zeige EGFR Proteine) genes are associated with overexpression of CDH5 through increased phosphorylation of EGFR (zeige EGFR Proteine) and downstream Akt (zeige AKT1 Proteine) pathways.

  2. We found that patients with chronic spontaneous urticaria (CSU) had significantly higher CDH5 serum levels compared with patients with atopic dermatitis and control subjects. Moreover, serum levels ofCDH5 were closely associated with the severity of CSU.

  3. Results indicate that the posthemorrhagic shock mesenteric lymph in vitro increases the cellular permeability of human umbilical vein endothelial cells through suppression of F-actin and VE-cadherin.

  4. CMTM3 (zeige CMTM3 Proteine) mediates cell-cell adhesion at adherens junctions and contributes to the control of vascular sprouting by regulation VE-cadherin turnover.

  5. Serum CDH5 correlates to poorer survival in patient with hormone-refractory metastatic breast cancer.

  6. Lateral accumulation of cadherin fingers in follower cells precedes turning, and increased actomyosin contractility can initiate cadherin finger extension as well as engulfment by a neighbouring cell, to promote follower behaviour.

  7. the conserved targeting of VE-cadherin by miR (zeige MLXIP Proteine)-22 regulates endothelial inflammation, tissue injury, and angiogenesis.

  8. High serum VE-cadherin expression is associated with non-alcoholic fatty liver disease.

  9. CDH5 may play a key role in the progression or metastasis of differentiated-type gastric cancer and serve as a target for its treatment.

  10. PDE4D (zeige PDE4D Proteine) acts to allow cAMP-elevating agents to regulate VECADs' role as a sensor of flow-associated fluid shear stress (FSS)-encoded information in arterial endothelial cells.

Cow (Bovine) Cadherin 5 (CDH5) Interaktionspartner

  1. VE-cadherin induces opposing growth signals.

  2. investigated the role of catenin p120 (zeige CTNND1 Proteine)-VE-cadherin interaction in regulation of barrier function in confluent endothelial monolayers

  3. Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA (zeige RHOA Proteine)

  4. a VE-cadherin-dependent pathway may link T2-TrpRS (zeige WARS Proteine) to inhibition of new blood vessel formation

  5. results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network

  6. exposure of BAECs to hydrostatic pressure (PHYSIOLOGIC PRESSURE) may downregulate the expression of VE-cadherin, resulting in loss of contact inhibition followed by increased proliferation and formation of a multilayered structure

  7. In all, these results demonstrate that cell-cell contact signals through VE-cadherin, RhoA, and intracellular tension in the actin cytoskeleton to regulate proliferation.

Pig (Porcine) Cadherin 5 (CDH5) Interaktionspartner

  1. Low expressions of eNOS3 and Ve-cadherin in the salvaged sub-healthy microvascular endothelium of infarcted and marginal areas suggest that endothelial system is impaired at 7-day of reperfused acute myocardial infarction.

Cadherin 5 (CDH5) Protein Überblick

Protein Überblick

This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.

Alternative names and synonyms associated with Cadherin 5 (CDH5)

  • cadherin 5, type 2 (vascular endothelium) (CDH5)
  • cadherin 5 (Cdh5)
  • cadherin 5 (cdh5)
  • cadherin 5, type 2 (vascular endothelium) (Cdh5)
  • 7B4 Protein
  • AA408225 Protein
  • cadherin-5 Protein
  • CD144 Protein
  • VE-Cad Protein
  • Vec Protein
  • VEcad Protein
  • VECD Protein
  • wu:fc88a07 Protein

Bezeichner auf Proteinebene für Cadherin 5 Proteine (CDH5)

cadherin 5, type 2, VE-cadherin (vascular endothelium) , cadherin 5, type 2, VE-cadherin (vascular epithelium) , 7B4/cadherin-5 , VE-cadherin , cadherin-5 , vascular endothelial cadherin , VE-cadherin (vascular epithelium) , fc88a07 , type 2 , vecdn , 7B4 antigen , cd144 antigen , endothelial-specific cadherin , VE cadherin

GENE ID SPEZIES
467991 Pan troglodytes
12562 Mus musculus
307618 Rattus norvegicus
445471 Danio rerio
1003 Homo sapiens
414735 Bos taurus
100727685 Cavia porcellus
414737 Sus scrofa
489775 Canis lupus familiaris
374068 Gallus gallus
101107462 Ovis aries
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