Caveolin 3 Proteine (CAV3)

Bezeichnung:
Caveolin 3 Proteine (CAV3)
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Synonyme:
AI385751, Cav-3, CAV3, caveolin-3, im:6902906, LGMD1C, LOC733765, LQT9, M-cav, VIP-21, VIP21, zgc:109710
alle Proteine anzeigen Gen GeneID UniProt
CAV3 859 P56539
CAV3 12391 P51637
CAV3 29161 P51638

Weitere Synonyme anzeigen

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Am meisten referenzierte Caveolin 3 Proteine

  1. Human Caveolin 3 Protein expressed in Wheat germ - ABIN1348152 : Sawada, Ishikawa, Tanji, Nakachi, Senba, Okudaira, Uchihara, Taira, Ohshiro, Yamada, Tanaka, Uezato, Ohshima, Sasai, Burgering, Duc Dodon, Fujii, Sunakawa, Mori: Overexpression of caveolin-1 in adult T-cell leukemia. in Blood 2010 (PubMed)

Weitere Proteine zu Caveolin 3 Interaktionspartnern

Zebrafish Caveolin 3 (CAV3) Interaktionspartner

  1. Cav3 is involved in muscle development and is required for correct intracellular organization and myoblast fusion.

Human Caveolin 3 (CAV3) Interaktionspartner

  1. The caveolin 3 G56S variant is not a clearly pathogenic mutation, but may influence cellular functions and morphologies resulting in an increased cellular vulnerability in terms of a modifying factor.

  2. Our results indicate that HCN4 (zeige HCN4 Proteine) channel function is modulated by cav-3. LQTS-associated mutations of cav-3 differentially influence pacemaker current properties indicating a pathophysiological role in clinical manifestations.

  3. This study demonstrated that the Caveolin-3 is aberrantly expressed in skeletal muscle cells in myasthenia gravis.

  4. Study characterized the secondary structure, dynamics, and topology of a lipidated full-length human Cav3 construct, demonstrated that the N-terminal domain undergoes a dramatic topological rearrangement in both micelles and vesicles that is reversibly mediated by pH

  5. The Cav3 P104L mutation of limb girdle muscular dystrophy-1C leads to disordered glucose metabolism in muscle cells.

  6. Data (including data from studies using recombinant proteins that lack typical in-vivo post-translational modifications such as palmitoylation) suggest Cav3 exhibits little tendency to partition into liquid-ordered domains of unilamellar vesicles.

  7. MURC/cavin-4 (zeige MURC Proteine), especially in combination with Cav-3, may play a consistent role in the differentiation process of rhabdomyosarcoma.

  8. This study demonstrated that cav3 mutation in stinct disorders including limb-girdle muscular dystrophy 1C, rippling muscle disease, and isolated creatine kinase elevation in Greece.

  9. In a nonreferred nationwide Danish cohort of SIDS (zeige IDS Proteine) cases, up to 5/66 (7.5%) of SIDS (zeige IDS Proteine) cases can be explained by genetic variants in the sodium channel complex genes.

  10. our results indicate that inhibition of Cav3 currents by 5,6-epoxyeicosatrienoic acid is an important mechanism controlling the vascular tone.

Mouse (Murine) Caveolin 3 (CAV3) Interaktionspartner

  1. Data show that caveolin-3 binds to low glycosylated extracellular matrix metalloproteinase inducer (LG-EMMPRIN) in cardiac cells and in the hearts of healthy mice.

  2. The Cav3 P104L mutation of limb girdle muscular dystrophy-1C leads to disordered glucose metabolism in muscle cells.

  3. Cav-3 overexpressing mice have changes in ECG intervals, heart rates, and cardiac ion channel expression

  4. Loss of CAV3 interferes with downstream insulin (zeige INS Proteine) signaling and lipid uptake and increases susceptibility to palmitate-induced insulin (zeige INS Proteine) resistance.

  5. eNOS (zeige NOS3 Proteine), caveolin-3, and connexin-43 (zeige GJA1 Proteine) were detected in subsarcolemmal mitochondria

  6. Data show increased expression of T-type Ca(2 (zeige CA2 Proteine)+) current and association of protein kinase C alpha (PKCalpha (zeige PKCa Proteine)) with caveolin-3 (Cav-3)was disrupted in the hypertrophic ventricular myocyte.

  7. Cardioprotection in myocardial infarction is abolished in caveolin-3 knockout mice.

  8. The lithogenic diet was associated with significantly lower CAV3 in the liver and lower CAV3 and CCKAR in the gallbladder compared with the control mice.

  9. Cav-3 may be a novel participant in B-cell expression, T-cell cytokine production and activation of inflammation

  10. Cav3 protein can modify integrin function and mechanotransduction in the cardiomyocyte and intact heart

Pig (Porcine) Caveolin 3 (CAV3) Interaktionspartner

  1. cloned and characterized caveolin-3 from porcine muscle; caveolin-3 was expressed specifically in skeletal muscle & heart; first evidence that caveolin-3 has a certain regulated expression pattern during the prenatal period of skeletal muscle development

Caveolin 3 (CAV3) Protein Überblick

Protein Überblick

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Alternative names and synonyms associated with Caveolin 3 (CAV3)

  • caveolin-3-like (LOC100058881)
  • caveolin 3 (CAV3)
  • caveolin 3, gene 2 (cav3.2)
  • caveolin 3 (cav3)
  • caveolin 3 (LOC733765)
  • caveolin 3, gene 1 (cav3.1)
  • caveolin-3 (Cav-3)
  • Caveolin-3 (cav3)
  • caveolin 3 (Cav3)
  • AI385751 Protein
  • Cav-3 Protein
  • CAV3 Protein
  • caveolin-3 Protein
  • im:6902906 Protein
  • LGMD1C Protein
  • LOC733765 Protein
  • LQT9 Protein
  • M-cav Protein
  • VIP-21 Protein
  • VIP21 Protein
  • zgc:109710 Protein

Bezeichner auf Proteinebene für Caveolin 3 Proteine (CAV3)

caveolin-3 , calveolin 3 , caveolin 3 , Caveolin-3 , M-caveolin

GENE ID SPEZIES
100058881 Equus caballus
378796 Gallus gallus
379866 Xenopus laevis
449679 Danio rerio
733765 Xenopus (Silurana) tropicalis
738786 Pan troglodytes
100125124 Xenopus (Silurana) tropicalis
398390 Xenopus laevis
100196833 Salmo salar
100528411 Ictalurus punctatus
859 Homo sapiens
12391 Mus musculus
29161 Rattus norvegicus
484671 Canis lupus familiaris
641358 Sus scrofa
615310 Bos taurus
101107228 Ovis aries
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