CEBPA Proteine (CEBPA)

Bezeichnung:
CCAAT/enhancer Binding Protein (C/EBP), alpha Proteine (CEBPA)
Auf www.antikoerper-online.de finden Sie aktuell 11 CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CEBPA Antikörper (157) und CEBPA Kits (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 218 CEBPA Produkte verfügbar.
Synonyme:
C/EBP, C/EBP-alpha, c/ebpa, C/EBP alpha, C/EBPalpha, cb1062, CBF-A, cC/EBP, Cebp, DBPCEP, wu:fj20f03, xC/EBP
alle Proteine anzeigen Gen GeneID UniProt
CEBPA 1050 P49715
CEBPA 12606 P53566
CEBPA 24252 P05554

Weitere Synonyme anzeigen

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Am meisten referenzierte CEBPA Proteine

  1. Human CEBPA Protein expressed in Escherichia coli (E. coli) - ABIN666625 : Gombart, Hofmann, Kawano, Takeuchi, Krug, Kwok, Larsen, Asou, Miller, Hoelzer, Koeffler: Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias. in Blood 2002 (PubMed)
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Weitere Proteine zu CEBPA Interaktionspartnern

Human CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Interaktionspartner

  1. High CEBP expression is associated with glioblastomas.

  2. identified high frequencies of mutations in CEBPA (32.7%), GATA2 (zeige GATA2 Proteine) (22.4%), NPM1 (zeige NPM1 Proteine) (15.5%), SETBP1 (zeige SETBP1 Proteine) (12.1%) and U2AF1 (zeige U2AF1 Proteine)

  3. our data show that excess p30 (zeige CENPV Proteine) cooperated with TRIB2 (zeige TRIB2 Proteine) only in the presence of p42 (zeige EPB42 Proteine) to accelerate acute myeloid leukaemia (AML (zeige RUNX1 Proteine)), and the direct interaction and degradation of C/EBPa p42 (zeige EPB42 Proteine) is required for TRIB2 (zeige TRIB2 Proteine)-mediated AML (zeige RUNX1 Proteine).

  4. A single +42-kb enhancer is essential for CEBPA expression in myeloid cells only.

  5. Co-occurrence of mutations in CSF3R (zeige CSF3R Proteine) and CEBPA in a well-defined acute myeloid leukemia (zeige BCL11A Proteine) subset, which uniformly responds to JAK (zeige JAK3 Proteine) inhibitors; this paves the way to personalized clinical trials for this disease.

  6. we established a reliable and straightforward screening method, based simply on the multidimensional analysis of widely available phenotypic parameters, suitable for large-scale detection of CEBPA-dm status and potentially able to overcome technical issues related to molecular methods.

  7. This study of a large multi-generational pedigree reveals that a germline mutation in the C-terminal bZip domain can alter the ability of C/EBP-alpha to bind DNA and reduces transactivation, leading to acute myeloid leukemia (zeige BCL11A Proteine).

  8. SBDS (zeige SBDS Proteine) function is specifically required for efficient translation re-initiation into the protein isoforms C/EBPalpha-p30 (zeige CENPV Proteine) and C/EBPbeta (zeige CEBPB Proteine)-LIP, which is controlled by a single cis (zeige CISH Proteine)-regulatory upstream open reading frame (uORF) in the 5' untranslated regions (5' UTRs) of both mRNAs.

  9. SHP2 (zeige PTPN11 Proteine)-ERK2 (zeige MAPK1 Proteine) signaling acts upstream of C/EBPalpha as a regulator of cell surface I antigen synthesis.

  10. the importance of C/EBPalpha for neutrophil maturation, its role in myeloid priming of hematopoietic stem and progenitor cells, and its indispensable requirement for AML (zeige RUNX1 Proteine) development.

Mouse (Murine) CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Interaktionspartner

  1. results indicate that JMJD2B regulates PPARgamma (zeige PPARG Proteine) and C/EBPalpha during adipogenesis

  2. A single +42-kb enhancer is essential for CEBPA expression in myeloid cells only.

  3. these data indicate that CycC (zeige CCNC Proteine) activates adipogenesis in part by stimulating the transcriptional activity of C/EBPalpha.

  4. Taken together, these findings demonstrate that artesunate inhibits adipogenesis in 3T3-L1 preadipoytes through the reduced expression and/or phosphorylation levels of C/EBP-alpha, PPAR-gamma (zeige PPARG Proteine), FAS (zeige FAS Proteine), perilipin A (zeige PLIN1 Proteine), and STAT-3 (zeige STAT3 Proteine).

  5. we show that SIX1 (zeige SIX1 Proteine) binds to adipogenic and brown marker genes and interacts with C/EBPa, C/EBPb (zeige CEBPB Proteine) and EBF2 (zeige EBF2 Proteine), suggesting their functional cooperation during adipogenesis.

  6. these results indicate that C/EBPalpha functions throughout osteoclastogenesis as well as in Osteoclast function. This study provides additional understanding of the roles of C/EBPalpha in Osteoclast biology.

  7. the DNA sequences to which EVI1 (zeige MECOM Proteine) binds at +35 and +37 kb and show that mutation of one of these releases Cebpa from EVI1 (zeige MECOM Proteine)-induced suppression.

  8. The efficient repression of E2F (zeige E2F1 Proteine) dependent S-phase genes and the activation of differentiation genes reside in the balanced DNA binding capacity of C/EBP alpha.

  9. Cebpa enhancers and silencers in a transcriptional model have roles in hematopoietic lineage specification

  10. Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha) directly regulates Kruppel-like factor 4 (Klf4 (zeige KLF4 Proteine)) expression and increasing the levels of histone demethylase (zeige MBD2 Proteine) Lsd1 (zeige KDM1A Proteine) and transcription factor Brd4 (zeige BRD4 Proteine) in B cell.

Zebrafish CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Interaktionspartner

  1. C/ebpalpha plays a role in liver growth regulation via the p53 (zeige TP53 Proteine) pathway.

  2. Dnmt1 (zeige DNMT1 Proteine) is required for hematopoietic stem and progenitor cells maintenance via cebpa regulation during definitive hematopoiesis in zebrafish

  3. Data suggest that upregulation of 10-formyltetrahydrofolate dehydrogenase (FDH (zeige ALDH1L1 Proteine)) involving CEBPalpha helps relieve embryonic oxidative stress induced (zeige SQSTM1 Proteine) by ethanol exposure.

  4. Bmi1 (zeige BMI1 Proteine) acts immediately downstream of CCAAT enhancer binding protein-alpha to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.

  5. Results provide first evidence that sumoylation of Cebp-alpha (via SUMO1 (zeige SUMO1 Proteine), SUMO2 (zeige SUMO2 Proteine), and SUMO3 (zeige SUMO3 Proteine)) might contribute to cell fate decision of myelo-erythroid progenitor cells in intermediate cell mass during primitive [extramedullary] hematopoiesis.

  6. An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 (zeige CTNNA1 Proteine) axis controls myeloid development and transformation.

Xenopus laevis CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Interaktionspartner

  1. a C/EBP recognition sequence in the proximal promoter region of C/EBPalpha is essential for IL-6 (zeige IL6 Proteine)-mediated repression

Cow (Bovine) CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Interaktionspartner

  1. These results suggest that the CEBPA gene is a strong candidate gene that affects carcass traits in Qinchuan cattle.

  2. Expressions of C-EBPalpha and myostatin (zeige MSTN Proteine) in muscles were higher in the concentrate-fed group than in the grass hay (zeige GTF2H5 Proteine)-fed group.

Pig (Porcine) CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Interaktionspartner

  1. C/EBPalpha is an essential regulatory factor for perilipin5 transcription and suggest that fasting stimulates perilipin5 transcription through influencing C/EBPalpha expression.

  2. The differential expression of specific CEBPA/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.

CEBPA Protein Überblick

Protein Überblick

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Alternative names and synonyms associated with CEBPA

  • CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA)
  • CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa)
  • CCAAT/enhancer binding protein (C/EBP), alpha (cebpa)
  • CCAAT/enhancer-binding protein alpha-like (LOC100358602)
  • C/EBP Protein
  • C/EBP-alpha Protein
  • c/ebpa Protein
  • C/EBP alpha Protein
  • C/EBPalpha Protein
  • cb1062 Protein
  • CBF-A Protein
  • cC/EBP Protein
  • Cebp Protein
  • DBPCEP Protein
  • wu:fj20f03 Protein
  • xC/EBP Protein

Bezeichner auf Proteinebene für CEBPA

CCAAT/enhancer-binding protein alpha , C/EBP alpha , CAAT/enhancer-binding protein DNA-binding protein , CAAT/enhancer-binding protein, DNA-binding protein , CCAAT/enhancer binding protein, alpha , chunp6777 , fj20f03 , c/EBP alpha , CCAAT/enhancer binding protein alpha

GENE ID SPEZIES
1050 Homo sapiens
12606 Mus musculus
24252 Rattus norvegicus
140815 Danio rerio
379967 Xenopus laevis
281677 Bos taurus
427549 Gallus gallus
397307 Sus scrofa
100358602 Oryctolagus cuniculus
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