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anti-Human Thrombospondin 1 Antikörper:
anti-Rat (Rattus) Thrombospondin 1 Antikörper:
anti-Mouse (Murine) Thrombospondin 1 Antikörper:
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Cow (Bovine) Monoclonal Thrombospondin 1 Primary Antibody für BP, ICC - ABIN151527
Cupi, Sarra, De Nitto, Franzè, Marafini, Monteleone, Del Vecchio Blanco, Paoluzi, Di Fusco, Gentileschi, Ortenzi, Colantoni, Pallone, Monteleone: Defective expression of scavenger receptors in celiac disease mucosa. in PLoS ONE 2014
Show all 4 Pubmed References
Human Polyclonal Thrombospondin 1 Primary Antibody für ELISA, WB - ABIN4359279
Pan, Chang, Chuang, Hung: The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells. in Experimental biology and medicine (Maywood, N.J.) 2008
Genetic variants of THBS1 were significantly more frequent in patients affected by idiopathic/genetic generalized epilepsies than in non-epileptic controls.
In pulmonary hypertension TSP1-CD47 (zeige CD47 Antikörper) is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.
High THBS1 expression is associated with primary effusion lymphoma.
Results show that the presence of OPN (zeige SPP1 Antikörper) and TSP-1 in the serum of patients with non-small cell lung cancer may reflect the aggressiveness of the tumor.
KLK4 (zeige KLK4 Antikörper) further liberated an N-terminal product, with purported angiogenic activity, from thrombospondin-1 (TSP1) and cleaved TSP1 in an osteoblast-derived matrix.
Data suggest pituitary cells secrete factor (TSP1) that binds to and inhibits action of BMP2 and BMP4; von Willebrand type C domain of TSP1 is likely responsible for this BMP2/4-binding activity. These studies were initially conducted using cultured cells from ovine pituitary gland and mouse cell line; interactions were confirmed using recombinant human proteins. (TSP1 = thrombospondin-1; BMP = bone morphogenetic protein)
the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1/CD47 (zeige CD47 Antikörper) axis may represent a valuable therapeutic alternative for hampering melanoma spreading.
The levels of CD36 (zeige CD36 Antikörper), STAT3 (zeige STAT3 Antikörper) and TGFbetaR2 mRNA were significantly higher in the TSP1-high group.
Study discovered novel and independent associations of prediabetes and related traits with MASP1 (zeige MASP1 Antikörper), and some evidence for associations with THBS1, GPLD1 (zeige GPLD1 Antikörper) and ApoA-IV (zeige APOA4 Antikörper), suggesting a role for these proteins in the pathophysiology of type 2 diabetes.
TSP-1 deficiency promotes maladaptive remodelling of the ECM (zeige MMRN1 Antikörper) leading to accelerated abdominal aortic aneurysms progression.
In pulmonary hypertension TSP1 (zeige GZMA Antikörper)-CD47 (zeige CD47 Antikörper) is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.
HIF-1alpha (zeige HIF1A Antikörper) induced angiogenesis by upregulating not only vascular endothelial growth factor but also miR (zeige MLXIP Antikörper)-21 via inhibiting a novel target gene TSP-1 (zeige GZMA Antikörper). Both of them may contribute to the protective effect of HIF-1alpha (zeige HIF1A Antikörper) on renal I/R injury.
the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1 (zeige GZMA Antikörper)/CD47 (zeige CD47 Antikörper) axis may represent a valuable therapeutic alternative for hampering melanoma spreading.
TSP-1 (zeige GZMA Antikörper) deficiency promotes maladaptive remodelling of the ECM (zeige MMRN1 Antikörper) leading to accelerated abdominal aortic aneurysms progression.
TSP-1 (zeige GZMA Antikörper) suppressed insulin (zeige INS Antikörper) signaling in cultured muscle cells, which was accompanied by the activation of stress signaling such as JNK (zeige MAPK8 Antikörper), p38 (zeige CRK Antikörper), and IKK (zeige CHUK Antikörper).
Three transcription factors were overexpressed and eleven underexpressed in TSP1 (zeige GZMA Antikörper)(-/-) compared to WT LGs (zeige LGSN Antikörper).
THSD1 (zeige THSD1 Antikörper) is a new regulator of endothelial barrier function during vascular development and protects intraplaque microvessels against haemorrhaging in advanced atherosclerotic lesions
Data indicate that thrombospondin-1 may contribute to a destructive macrophage response in dysferlinopathy and pose the intriguing possibility that thrombospondin-1 levels may serve as a biomarker for disease progression.
demonstrate that HIF-2alpha (zeige EPAS1 Antikörper) is clearly implicated in the TSP1 (zeige GZMA Antikörper) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction
Thrombospondin-1 was differentially expressed according to tumor grade, but not affected by p53 (zeige TP53 Antikörper) expression or mutational status
Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 (zeige THBS2 Antikörper) expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2 (zeige THBS2 Antikörper), up-regulates expression of FGF2 (fibroblast growth factor 2 (zeige FGF2 Antikörper)).
Thrombospondin has a role in inducing RhoA (zeige RHOA Antikörper) inactivation through FAK (zeige PTK2 Antikörper)-dependent signaling to stimulate focal adhesion disassembly
Thrombospondin-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.
Preincubation of erythroid cells with thrombospondin 1 eliminated the inhibitory activity of insulin (zeige INS Antikörper)-like growth factor
The cell-specific regulation of TSP-1 suggests a potential mechanism for the aberrant angiogenesis in diabetics and TSP-1 involvement in development of various vascular diabetic complications
The novel finding that TSP-1-induced migration is dependent on the CD44 (zeige CD44 Antikörper) receptor links 2 pathways thought to be disparate (ie, TSP-1 and HyA (zeige KDM5D Antikörper)).
These current studies were undertaken to determine how TSP-1 functions to modulate the smooth muscle cell response to IGF-I (zeige IGF1 Antikörper) and the mechanisms by which hyperglycemia regulates TSP-1 protein.
Increased TSP-1 expression in non-heart-beating donors may indicate a compensatory response to the reported diminished TGF-beta1 (zeige TGFB1 Antikörper) expression.
ELL (zeige ELL Antikörper) (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation
May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
, thrombospondin type-1 domain-containing protein 1
, thrombospondin, type I, domain 1
, transmembrane molecule with thrombospondin module
, cancer/testis antigen 36
, glyceraldehyde-3-phosphate dehydrogenase-like 5
, testis specific protein 1 (probe H4-1 p3-1)
, testis-specific protein TPX-1
, thrombospondin 1