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CAPNL1 Proteine (CAPNL1)

Bezeichnung:
Calpain 1, Large Subunit Proteine (CAPNL1)
Auf www.antikoerper-online.de finden Sie aktuell 17 Calpain 1, Large Subunit (CAPNL1) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CAPNL1 Antikörper (56) und CAPNL1 Kits (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 104 CAPNL1 Produkte verfügbar.
Synonyme:
CANP, CANP1, CANPL1, Capa-1, Capa1, mu-calpin, muCANP, muCL, si:ch211-203k12.4, si:dkeyp-101g1.3
alle Proteine anzeigen Gen GeneID UniProt
CAPNL1 12333 O35350
CAPNL1 823 P07384
CAPNL1 29153 P97571

Weitere Synonyme anzeigen

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Weitere Proteine zu CAPNL1 Interaktionspartnern

Mouse (Murine) Calpain 1, Large Subunit (CAPNL1) Interaktionspartner

  1. calpains and calpastatin (zeige CAST Proteine) in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (zeige TAGLN Proteine)-5HTT (zeige SLC6A4 Proteine)(+) strain) PH, were investigated.

  2. Attenuation of atherosclerotic lesions/inflammation in ApoE (zeige APOE Proteine) KO mice by simvastatin might be associated with the downregulation of CD36 (zeige CD36 Proteine) and calpain-1 (zeige CAPN1 Proteine).

  3. Leukocyte calpain-1 (zeige CAPN1 Proteine)/calpain-2 (zeige CAPN2 Proteine) deficiency reduces angiotensin II-induced inflammation and atherosclerosis but not abdominal Aortic aneurysms in mice.

  4. TnT3 regulates transcription of Cacna1s (zeige CACNA1S Proteine), the gene encoding Cav1.1 (zeige CACNA1S Proteine). Knocking down TnT3 in vivo downregulated Cav1.1 (zeige CACNA1S Proteine).

  5. Taken together, our findings suggested that DHRS7C maintains intracellular Ca(2+) homeostasis involving the ER/SR and that functional loss of DHRS7C leads to Ca(2+) overload in the cytosol and ER/SR, resulting in enlarged cellular morphology via calpain activation

  6. In conclusion, calpain was involved in oxygen glucose deprivation-induced RGC-5 necroptosis with the increased expression of its downstream molecule tAIF.

  7. CRYbetaA3/A1-crystallin has a role in preventing nuclear cataract impaired lysosomal cargo clearance and calpain activation

  8. Capn1 protein and activity in mitochondria were elevated in diabetic mouse hearts. Increased mitochondrial Capn1 was associated with increased mitochondrial ROS (zeige ROS1 Proteine) generation and oxidative damage and reduced ATP5A1 (zeige ATP5A1 Proteine) protein and ATP synthase activity.

  9. LOX-1 (zeige OLR1 Proteine) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (zeige CAPN1 Proteine) and -2.

  10. Over-expression of Cast inhibits calpain activation and attenuates post-infarction myocardial remodeling.

Human Calpain 1, Large Subunit (CAPNL1) Interaktionspartner

  1. calpains and calpastatin (zeige CAST Proteine) in patients with idiopathic pulmonary arterial hypertension (PAH) and mice with hypoxic or spontaneous (SM22 (zeige TAGLN Proteine)-5HTT (zeige SLC6A4 Proteine)(+) strain) PH, were investigated.

  2. calpain and protein kinase (zeige CDK7 Proteine) Calpha (zeige PRKACA Proteine) abnormal release promotes a constitutive release of matrix metalloproteinase 9 (zeige MMP9 Proteine) in peripheral blood mononuclear cells from cystic fibrosis (zeige S100A8 Proteine) patients

  3. our findings suggest that the gene/protein expression of both CAPN1 and CAPN2 (zeige CAPN2 Proteine), as well as the ERK1 (zeige MAPK3 Proteine) and ERK2 (zeige MAPK1 Proteine) genes and related proteins, could be molecular factors associated with more invasive tumor behavior in squamous cell laryngeal cancer.

  4. This study demonstrated that Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain.

  5. the calpain-dependent cleavage of Nav1.6 (zeige SCN8A Proteine) channels expressed in human embryonic kidney (HEK (zeige EPHA3 Proteine)) 293 cells caused the upregulation of I(NaP (zeige CTNNBL1 Proteine))

  6. Increased mu-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.

  7. Data indicate that calpain is responsible for processing translation termination factor eRF3 into its IAP-binding isoform p-eRF3.

  8. NOS (zeige NOS1 Proteine) stimulation via PI3K (zeige PIK3CA Proteine), calpain proteases, and SIRT1 (zeige SIRT1 Proteine)-dependent deacetylation downstream from VEGFR2 (zeige KDR Proteine) activation contributes to these vasodilator responses.

  9. Junctophilin-2 (zeige JPH2 Proteine) is cleaved by calpain at multiple sites, resulting in dysfunctional junctophilin-2 (zeige JPH2 Proteine) truncations.

  10. The results of this study indicated that reductions in kallikrein-6 and calpain-1 may contribute to the accumulation of alpha-synuclein in DLB.

Cow (Bovine) Calpain 1, Large Subunit (CAPNL1) Interaktionspartner

  1. This work is supportive of the importance of CAPN1 and CAST for mean tenderness in beef.

  2. Suppression of CANP1 resulted in the activation of caspase (zeige CASP3 Proteine) and heat-shock-protein systems which might in turn regulate apoptosis through the caspase (zeige CASP3 Proteine)-dependent cell death pathway. [CANP1]

  3. bovine CAPN-CAST interaction were well reflected in the geometry between the pharmacophore features and its shape constraints identified using our modeled bovine CAPN1/CAST4 complex structures

  4. This work confirms the importance of CAPN1 and CAST for tenderness in beef, provides a new effect of CAST on beef tenderness, and questions the utility of GHR (zeige GHR Proteine) as a selection marker for beef quality.

  5. It was found that the marker c.3379G > A in the CAPN1 gene influences the Ca content in the meat of this Nelore population, with the rare genotype associated with less Ca content.

  6. m- and micro-calpain immunosignals in the cytoplasm both along the Z disk/I band regions and in the form of intracellular stores.

  7. Association of polymorphisms in calpain 1 (zeige CAPN1 Proteine), (mu/I) large subunit, calpastatin (zeige CAST Proteine), and cathepsin D (zeige CTSD Proteine) genes with meat quality traits in double-muscled Piemontese cattle.

  8. Relationships of the calpain system with meat tenderness and carcass traits were examined for 94 purebred Angus bulls.

  9. The association of polymorphisms in calpastatin (zeige CAST Proteine) and mu-calpain genes with meat tenderness in 3 French beef breeds is reported.

  10. A new insertion/deletion (InDel) polymorphism, consisting of a change of seven nucleotides for only one nucleotide (TCTGGGT --> C) within intron 17 of the CAPN1 gene, is reported.

Pig (Porcine) Calpain 1, Large Subunit (CAPNL1) Interaktionspartner

  1. CAPN1 HM535412:g.157T > C showed effect on meat redness.

  2. The decreased expression of calpain 1A mRNA during development is highly correlated with muscle protein accumulation in neonatal Sus scrofa.

  3. Right ventricular (RV) dysfunction from acute RV pressure overload is, in part, due to activation of calpain, and calpain inhibition would therefore attenuate RV dysfunction.

  4. catalytic site amino acid residues 105-133 contained a disulfide bond between Cys (zeige DNAJC5 Proteine)(108) and Cys (zeige DNAJC5 Proteine)(115)

  5. Association of polymorphisms with breed characteristics indicated that the mutations in CAPN1 detected by P4, P6 primers and that resulting in the change of Hinf 1 recognition site may be related to lean meat percentage.

Rabbit Calpain 1, Large Subunit (CAPNL1) Interaktionspartner

  1. The activities of Calpain and PLA2 (zeige YWHAZ Proteine) on the muscle tissue of the bladders were analyzed.

CAPNL1 Protein Überblick

Protein Überblick

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with CAPNL1

  • calpain 1, (mu/I) large subunit (capn1)
  • calpain 1, (mu/I) large subunit b (capn1b)
  • calpain 1 (Capn1)
  • calpain 1, (mu/I) large subunit (CAPN1)
  • calpain 1, (mu/I) large subunit (Capn1)
  • CANP Protein
  • CANP1 Protein
  • CANPL1 Protein
  • Capa-1 Protein
  • Capa1 Protein
  • mu-calpin Protein
  • muCANP Protein
  • muCL Protein
  • si:ch211-203k12.4 Protein
  • si:dkeyp-101g1.3 Protein

Bezeichner auf Proteinebene für CAPNL1

calpain 1, large subunit , CANP 1 , calcium-activated neutral proteinase 1 , calpain mu-type , calpain-1 catalytic subunit , calpain-1 large subunit , micromolar-calpain , mu-calpain , muCANP , calpain, large polypeptide L1 , cell proliferation-inducing gene 30 protein , cell proliferation-inducing protein 30 , micromolar calcium activated neutral protease 1 , micromolar calcium-activated neutral protease 1 , mu-calpain large subunit

GENE ID SPEZIES
380177 Xenopus laevis
541454 Xenopus (Silurana) tropicalis
565106 Danio rerio
12333 Mus musculus
823 Homo sapiens
281661 Bos taurus
397027 Sus scrofa
100009089 Oryctolagus cuniculus
29153 Rattus norvegicus
693249 Gallus gallus
100174090 Pongo abelii
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