BMPR1B Antikörper (Middle Region)

Produktnummer ABIN3044052

Produktdetails anti-BMPR1B Antikörper

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Bindungsspezifität: AA 145-160, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMPR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Bone morphogenetic protein receptor type-1B(BMPR1B) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: FCYFRYKRQE TRPRYS

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Bone morphogenetic protein receptor type-1B(BMPR1B) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: bone morphogenetic protein receptor, type IB
Protein Name: Bone morphogenetic protein receptor type-1B

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human BMPR1B(145-160aa FCYFRYKRQETRPRYS), different from the related rat and mouse sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for BMPR1B is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu BMPR1B

Target: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Andere Bezeichnung: BMPR1B (BMPR1B Produkte)

Hintergrund: BMPR1B(Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein(BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine(threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al.(1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al.(1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

Synonyms: Activin receptor like kinase 6 antibody|Acvrlk6 antibody|ALK 6 antibody|ALK6 antibody|alk6tr antibody|BMP type-1B receptor antibody|BMPR IB antibody|BMPR-1B antibody|Bmpr1b antibody|BMPRIB antibody|BMR1B_HUMAN antibody|Bone morphogenetic protein receptor type 1B antibody|Bone morphogenetic protein receptor type IB antibody|Bone morphogenetic protein receptor type-1B antibody|BR 1b antibody|BR1b antibody|CDw 293 antibody|CDw293 antibody|CDw293 antigen antibody|CFK 43a antibody|CFK43a antibody|Serine/threonine receptor kinase antibody|zALK 6 antibody|zALK6 antibody

UniProt: O00238