SLC2A4 Proteine (SLC2A4)

Bezeichnung:
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 Proteine (SLC2A4)
Auf www.antikoerper-online.de finden Sie aktuell 6 Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SLC2A4 Antikörper (217) und SLC2A4 Kits (55) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 289 SLC2A4 Produkte verfügbar.
Synonyme:
Glut-4, glut4, slc2a4
alle Proteine anzeigen Gen GeneID UniProt
SLC2A4 6517 P14672
SLC2A4 20528 P14142
SLC2A4 25139 P19357

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Weitere Proteine zu SLC2A4 Interaktionspartnern

Horse (Equine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) Interaktionspartner

  1. Insulin (zeige INS Proteine) resistance was associated with a significantly reduced total GLUT4 content in omental adipose tissue, without a change in content in other visceral or subcutaneous adipose sites.

  2. There was a significant difference when pooled means for Glut-4 expression in muscle compared with adipose tissue from different anatomical sites.

Human Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) Interaktionspartner

  1. The results of the study confirmed the presence of GLUT-1 (zeige SLC2A1 Proteine), GLUT-4 and GLUT-9 proteins in the trophoblast from both, uncomplicated and diabetic pregnancies. In addition, insulin (zeige INS Proteine) therapy may increase placental expression of GLUT-4 and GLUT-9, and partially GLUT-1 (zeige SLC2A1 Proteine), in women with pregestational and gestational diabetes mellitus.

  2. our study has found that BMI, hypertension, myometrial invasion, pathological type, and Glut4 positive expression might be prognostic factors of EC [Endometrial cancer ]

  3. Our work highlights the convenience and efficiency of this novel pH-sensitive fluorescent probe and reveals the new biological activity of staurosporine as an agonist for GLUT4 translocation and as an effective insulin (zeige INS Proteine) additive analogue.

  4. studies demonstrate that Elmo2 (zeige ELMO2 Proteine) is a new regulator of insulin (zeige INS Proteine)-dependent Glut4 membrane translocation through modulating Rac1 activity and Akt (zeige AKT1 Proteine) membrane compartmentalization.

  5. This review focuses on recent advances on the role of these signaling pathways and transcription factors involved in the regulation of CD36 (zeige CD36 Proteine) and GLUT4.

  6. effects of physiologically relevant phospholipids on glucose transport in liposomes containing purified GLUT4 and GLUT3 (zeige SLC2A3 Proteine). The anionic phospholipids, phosphatidic acid, phosphatidylserine, phosphatidylglycerol, and phosphatidylinositol, were found to be essential for transporter function by activating it and stabilizing its structure.

  7. These results suggest that the initial event caused by overnutrition may be oxidative stress, which produces insulin (zeige INS Proteine) resistance, at least in part, via carbonylation and oxidation-induced inactivation of GLUT4.

  8. A single bout of exercise elicited similar GLUT4 translocation in skeletal muscle of PCOS and Controls. The absence of impairment in GLUT4 translocation suggests that PCOS patients with obesity and insulin (zeige INS Proteine) resistance may benefit from exercise training.

  9. SLC2A4 gene expression level was slightly lower within type 2 diabetic patients in both type of tissues. Furthermore, the negative correlation between SLC2A4 gene expression level in visceral adipose tissue and BMI has been noticed

  10. Leptin (zeige LEP Proteine) at concentrations used in the study does not change glucose transport into lymphocytes and seems to have no influence on the expression of GLUT1 (zeige SLC2A1 Proteine), GLUT3 (zeige SLC2A3 Proteine), GLUT4 and and leptin (zeige LEP Proteine) receptors

Pig (Porcine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) Interaktionspartner

  1. Feed intake remains low whereas respiratory frequency and body temperature remain higher and expression of HSP90 (zeige HSP90 Proteine), CAT1 (zeige SLC7A1 Proteine), SGLT1 (zeige SLC5A1 Proteine) and GLUT4 increases in some tissues in pigs under chronic heat stress conditions.

  2. TBC1D4 (zeige TBC1D4 Proteine), insulin receptor (zeige INSR Proteine) and GLUT4 showed altered expression in some tissues in pre-diabetic pigs.

  3. analysis of time- and breed-specific expression patterns of GLUT2 (zeige SLC2A2 Proteine) and GLUT4, which highlight their potential as candidate genes for assessing adipose deposition and muscle development in pigs

  4. Chronic elevated calcium blocks AMPK (zeige PRKAA1 Proteine)-induced GLUT-4 expression in skeletal muscle.

Mouse (Murine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) Interaktionspartner

  1. Data, including data from studies using knockout/transgenic mice, suggest that PrPC (zeige PRNP Proteine) is involved in development of insulin (zeige INS Proteine) resistance and obesity; primary embryonic fibroblasts cultured from PrPC (zeige PRNP Proteine) knockout mice exhibit reduced glucose uptake upon insulin (zeige INS Proteine) stimulation due to reduced translocation of glucose transporter Glut4 to cell membrane. (PrPC (zeige PRNP Proteine) = cellular prion protein (zeige PRNP Proteine); Glut4 = facilitated glucose transporter (zeige SLC2A12 Proteine) 4)

  2. Our findings implicate Rac1 as a regulatory element critical for controlling glucose uptake during exercise via regulation of GLUT4 translocation.

  3. insulin (zeige INS Proteine) and insulin (zeige INS Proteine) resistance regulate the spatial organization of GLUT4 in adipocytes.

  4. these results indicate that PI3K and Akt ( Akt1 (zeige AKT1 Proteine)-Akt3 (zeige AKT3 Proteine))play distinct roles, and that PI3K stimulates Akt (zeige AKT1 Proteine)-independent pathways that are important for GLUT4 translocation.

  5. We confirmed that procyanidins suppressed acute hyperglycemia with an oral glucose tolerance test in a dose-dependent manner.procyanidins, especially cinnamtannin A2, significantly ameliorate postprandial hyperglycemia at least in part by promoting GLUT4 translocation to the plasma membrane by activating both insulin (zeige INS Proteine)- and AMPK (zeige PRKAA1 Proteine)-signaling pathways.

  6. DHHC7 KO mice developed hyperglycemia and glucose intolerance, thereby confirming that DHHC7 represents the principal PAT for Glut4 and that this mechanism is essential for insulin (zeige INS Proteine)-regulated glucose homeostasis

  7. Brain GLUT4 knockout mice are glucose intolerant, insulin (zeige INS Proteine) resistant, and have impaired glucose sensing, indicating a critical role for brain GLUT4 in sensing and responding to changes in blood glucose.

  8. Glut4 expression in the gastrocnemius muscle was lowered under short photoperiod. Access to running wheels did not alter Glut4 expression in the gastrocnemius muscle. Photoperiodic changes in Glut4 expression may be independent of physical activity.

  9. SEC16A (zeige INPP5E Proteine) and RAB10 (zeige RAB10 Proteine) promote insulin (zeige INS Proteine)-stimulated mobilization of GLUT4 from a perinuclear recycling endosome/trans Golgi network compartment.

  10. these results indicate an indispensable role for Rab8A (zeige RAB8A Proteine) in insulin (zeige INS Proteine)-regulated GLUT4 trafficking in C2C12 cells.

Cow (Bovine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) Interaktionspartner

  1. Low GLUT1 (zeige SLC2A1 Proteine) and GLUT3 (zeige SLC2A3 Proteine) expression in nonclassical monocytes was unaltered during differentiation into macrophages. GLUT4 mRNA was only detectable in unstimulated macrophages. Neither monocytes nor macrophages were insulin (zeige INS Proteine) responsive.

  2. Results of the present study suggest that myostatin (zeige MSTN Proteine) inhibits the expression of GLUT4 mRNA and that the greater ability of double muscled cattle to produce muscle may be due to their greater sensitivity to insulin (zeige INS Proteine) and greater use of glucose.

  3. GLUT4 gene expression increased during late lactation.

SLC2A4 Protein Überblick

Protein Überblick

This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

Alternative names and synonyms associated with SLC2A4

  • solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4)
  • solute carrier family 2 (facilitated glucose transporter), member 4 (Slc2a4)
  • solute carrier family 2 (facilitated glucose transporter), member 4 (slc2a4)
  • solute carrier family 2 (facilitated glucose transporter), member 4 (GLUT4)
  • Glut-4 Protein
  • glut4 Protein
  • slc2a4 Protein

Bezeichner auf Proteinebene für SLC2A4

glucose transporter 4 , glucose transporter type 4 , solute carrier family 2, facilitated glucose transporter member 4 , solute carrier family 2 (facilitated glucose transporter), member 4 , solute carrier family 2, facilitated glucose transporter member 4-like , insulin-responsive glucose transporter , GLUT-4 , glucose transporter type 4, insulin-responsive , insulin-responsive glucose transporter type 4 , GT2 , Glucose transporter 4 insuline-responsive , Glucose transporter 4, insuline-responsive , solute carrier family 2 member 4 , solute carrier family 2 , member 4 , Insulin-responsive glucose transporter , GLUT4 , insulin-responsive glucose transporter 4

GENE ID SPEZIES
468443 Pan troglodytes
100033939 Equus caballus
100456448 Pongo abelii
100127021 Felis catus
6517 Homo sapiens
396754 Sus scrofa
20528 Mus musculus
25139 Rattus norvegicus
100037710 Oryctolagus cuniculus
282359 Bos taurus
444033 Xenopus laevis
403673 Canis lupus familiaris
100860891 Capra hircus
442992 Ovis aries
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