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MMP2 Proteine (MMP2)

Matrix Metalloproteinase 2 Proteine (MMP2)
Auf finden Sie aktuell 52 Matrix Metalloproteinase 2 (MMP2) Proteine von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MMP2 Antikörper (396) und MMP2 Kits (132) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 593 MMP2 Produkte verfügbar.
2-MMP, anon-WO0118547.84, CG1794, CLG4, CLG4A, dm-2MMP, Dm2-MMP, Dmel\\CG1794, dmmp2, fgmmp-2, GelA, l(2)02353, LOC100135793, MMP-2, MMP-II, mmp2, MONA, TBE-1, wu:fa99h12, wu:fk89d01
alle Proteine anzeigen Gen GeneID UniProt
MMP2 81686 P33436
MMP2 17390 P33434
MMP2 4313 P08253

Weitere Synonyme anzeigen

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Am meisten referenzierte MMP2 Proteine

  1. Human MMP2 Protein expressed in Human Cells - ABIN2002031 : Brooks, Silletti, von Schalscha, Friedlander, Cheresh: Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. in Cell 1998 (PubMed)
    Zeige alle 7 Referenzen für ABIN2002031

  2. Human MMP2 Protein expressed in HEK-293 - ABIN2666503 : Itoh, Ikeda, Gomi, Nakao, Suzuki, Itohara: Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice. in The Journal of biological chemistry 1997 (PubMed)
    Zeige alle 7 Referenzen für ABIN2666503

  3. Mouse (Murine) MMP2 Protein expressed in HEK-293 - ABIN2666506 : Hoikkala, Pääkkö, Soini, Mäkitaro, Kinnula, Turpeenniemi-Hujanen: Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma. in Cancer letters 2006 (PubMed)
    Zeige alle 7 Referenzen für ABIN2666506

  4. Mouse (Murine) MMP2 Protein expressed in Human Cells - ABIN2008781 : Fernandez-Patron, Radomski, Davidge: Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor. in Circulation research 1999 (PubMed)
    Zeige alle 5 Referenzen für ABIN2008781

  5. Human MMP2 Protein expressed in HEK-293 Cells - ABIN2181511 : Fernandez-Patron, Stewart, Zhang, Koivunen, Radomski, Davidge: Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction. in Circulation research 2000 (PubMed)
    Zeige alle 5 Referenzen für ABIN2181511

  6. Human MMP2 Protein expressed in Mouse - ABIN593510 : Masui, Doi, Koshiba, Fujimoto, Tsuji, Nakajima, Koizumi, Toyoda, Tulachan, Ito, Kami, Mori, Wada, Noda, Imamura: RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis. in Clinical cancer research : an official journal of the American Association for Cancer Research 2003 (PubMed)

  7. Human MMP2 Protein expressed in Escherichia coli (E. coli) - ABIN1080273 : Zheng, Hu, Huang, Xu, Yang, Li: In vivo bioengineered ovarian tumors based on collagen, matrigel, alginate and agarose hydrogels: a comparative study. in Biomedical materials (Bristol, England) 2015 (PubMed)

Weitere Proteine zu MMP2 Interaktionspartnern

Horse (Equine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. study demonstrated that matrix metalloproteinase 1 (zeige MMP1 Proteine) and 2 might be fundamental for events related to equine tissue remodeling, which occurs during follicular development

Fruit Fly (Drosophila melanogaster) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. We also show that follicular OA-Oamb signaling induces Mmp2 enzymatic activation but not Mmp2 protein expression, likely via intracellular Ca2 (zeige CA2 Proteine)+ as the second messenger.

  2. Finally, matrix metalloproteinase 2 (Mmp2), a type of protease thought to facilitate mammalian ovulation, is expressed in mature follicle and corpus luteum cells.

  3. As a Wnt (zeige WNT4 Proteine) signaling antagonist, MMP2 cleaves the glypican (zeige GPC1 Proteine), reducing the ability of Dlp (zeige DMD Proteine) to interact with the Wnt (zeige WNT4 Proteine) ligand and promote its distribution.

  4. Matrix metalloproteinase 2 is required for fat-body remodeling in Drosophila

  5. Drosophila MMP2 regulates the matrix molecule faulty attraction (Frac) to promote motor axon targeting in Drosophila.

  6. Dendrite reshaping of adult Drosophila sensory neurons requires matrix metalloproteinase MMP2-mediated modification of the basement membranes

  7. Mmp2 expression in the developing air sac (zeige ADCY10 Proteine) is controlled by the Drosophila FGF homolog Branchless and then participates in a negative feedback and lateral inhibition mechanism that defines the precise pattern of FGF signaling.

  8. findings demonstrate a critical role for Mmp2 in tubulogenesis post-induction, and implicate Mmp2 in regulating dynamic and essential changes to the extracellular matrix

Zebrafish Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. Dexamethasone and hydrocortisone alter expression and activity of MMP-2 and MMP-9 (zeige MMP9 Proteine) in the embryonic zebrafish.

Mouse (Murine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. These results indicate that increased MMP2 and MMP9 (zeige MMP9 Proteine) activity in the brains of mouse adenovirus type 1-infected susceptible mice may be due to MMP activity produced by endothelial cells, astrocytes, and microglia, which in turn may contribute to blood-brain barrier disruption and encephalitis in susceptible mice.

  2. Studies define a novel HMGA1 (zeige HMGA1 Proteine)-MMP-2 pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  3. activation of astrocyte MMP2/JNK1 (zeige MAPK8 Proteine)/2 contributes to the pathogenesis of pain hypersensitivity in the complex regional pain syndrome model

  4. Ceramide 1-phosphate -stimulated macrophage migration is a receptor mediated effect, and point to MMP-2 and -9 as possible therapeutic targets to control inflammation.

  5. MMP-2 potentiates shear-induced platelet activation by enhancing thrombus formation

  6. Identify novel MMP-2/cardiac sPLA2 (zeige PLA2G2A Proteine) pathway that endows the heart with important endocrine functions, including regulation of inflammation and lipid metabolism in the liver.

  7. 129/SvEv mice are more susceptible to abdominal aortic aneurysms compared to C57Bl/6 mice and suggest roles for MMP2/9.

  8. Report cross-talk between macrophages, smooth muscle cells, and endothelial cells in response to cigarette smoke alters MMP2/9 levels.

  9. MMP-2 silenced hypoxic fibroblasts under hyperglycemic conditions have impaired angiogenic potential. Collagen I/IV secretion is decreased and cell migration is prevented.

  10. N-terminal truncated isoform-MMP-2, but not full-length-MMP-2, is the major isoform of MMP-2 involved in skeletal muscle Ischemia-reperfusion injury.

Human Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. MMP-2 735C/T SNPs are associated with resistant hypertension.

  2. Potential immune markers, including interleukin 1 receptor antagonist (zeige IL1RN Proteine), interferon gamma-inducible protein 10 (zeige CXCL10 Proteine), hepatocyte growth factor (zeige HGF Proteine), soluble p75 (zeige CUX1 Proteine) tumor necrosis factor alpha receptor (zeige TNFRSF1A Proteine), vascular cell adhesion molecule 1 (zeige VCAM1 Proteine), and matrix metalloproteinase 2, were significantly associated with significant plasma leakage during Dengue virus infection.

  3. miR (zeige MLXIP Proteine)-888-5p increased the expression of MMP-2 and MMP-9 (zeige MMP9 Proteine) proteins that promoted cell migration and invasion, and decreased the expression of p53 (zeige TP53 Proteine) protein which further enhanced the cell tumorigenicity.

  4. Studies indicate that in the advanced stage of chronic kidney disease (CKD), the activity of matrix metalloproteinase (zeige MMP20 Proteine) (MMPs)MMP-2 and 9 is decreased and leads to inadequate degradation of extracellular matrix (ECM (zeige MMRN1 Proteine)).

  5. Bradykinin promoted migration and invasion of hepatocellular carcinoma cells through TRPM7 (zeige TRPM7 Proteine) and MMP2.

  6. MMP-2 could be a candidate marker for real-time detection of chondrogenic differentiation of human adipose-derived stem cells

  7. miR (zeige MLXIP Proteine)-346 and miR (zeige MLXIP Proteine)-582-3p regulate EG-VEGF (zeige Prok1 Proteine)-induced trophoblast invasion through repressing MMP 2 and MMP 9 (zeige MMP9 Proteine), and may become novel diagnostic biomarkers or therapeutic targets for EG-VEGF (zeige Prok1 Proteine)-related obstetric disorders. (c) 2016 BioFactors, 43(2):210-219, 2017.

  8. This study evaluated serum levels of MMP-9 (zeige MMP9 Proteine) and -2 as biomarkers of trichinellosis in patients who had acquired the infection from raw or undercooked wild boar meat.

  9. Studies define a novel HMGA1 (zeige HMGA1 Proteine)-MMP-2 pathway involved in a subset of human carcinosarcomas and tumor progression in murine models.

  10. The results of our pilot study indicated the diagnostic potential of miR (zeige MLXIP Proteine)-29b and MMP-2, an inverse association between miR (zeige MLXIP Proteine)-26a and MMP-2, and proved the role of MMP-2 and miR (zeige MLXIP Proteine)-26a, miR (zeige MLXIP Proteine)-29b and miR (zeige MLXIP Proteine)-519d in lung carcinogenesis

Cow (Bovine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. NADPH oxidase (zeige NOX1 Proteine) plays an important role in proMMP-2 expression and activation and MMP-2 mediated SMC (zeige DYM Proteine) proliferation occurs through the involvement of Spm (zeige NPC1 Proteine)-Cer (zeige CBLN1 Proteine)-S1P (zeige MBTPS1 Proteine) signaling axis under ANG II (zeige AGT Proteine) stimulation of PASMCs

  2. The expression patterns of MMP1 (zeige MMP1 Proteine), MMP2, and MMP8 (zeige MMP8 Proteine) were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1 (zeige MMP1 Proteine), MMP2, and MMP8 (zeige MMP8 Proteine) expression levels with meat quality traits were analyzed in cattle. The expression of MMP1 (zeige MMP1 Proteine), MMP2, and MMP8 (zeige MMP8 Proteine) were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

  3. The results showed that a decrease in MMP-1 (zeige MMP1 Proteine) and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

  4. Activation of cytosolic MMP-9 (zeige MMP9 Proteine) and MMP-2 was investigated in the retinal endothelial cells incubated in high glucose for 6-96 h, and correlated with their mitochondrial accumulation and mitochondrial damage.

  5. Data indicate the involvement of PKC-alpha (zeige PKCa Proteine) in proMMP-2 activation and inhibition of TIMP-2 (zeige TIMP2 Proteine) expression by NF-kappaB (zeige NFKB1 Proteine)-MT1-MMP (zeige MMP14 Proteine)-dependent and -independent pathway.

  6. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2; MMP-14 (zeige MMP14 Proteine)) in endometrial stromal cells; expression of stromal MMPs is significantly higher in coculture with epithelial cells.

  7. Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase activity, but the pretreatment with TIMP-2 (zeige TIMP2 Proteine) inhibits the increase in the enzyme activity

  8. A differential pattern of matrix metalloproteinase-2 and Tissue inhibitor metalloproteinase-2 was observed in cow uteri with adenomyosis.

  9. MMP-14 (zeige MMP14 Proteine), MMP-2 and TIMP-2 (zeige TIMP2 Proteine) are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.

  10. Results describe distinct changes in expression of MMP2, MMP14 (zeige MMP14 Proteine), and the metallopeptidase (zeige ECEL1 Proteine) inhibitor TIMP2 (zeige TIMP2 Proteine) between different phases of the estrous cycle indicating an endocrine regulation.

Pig (Porcine) Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (zeige MMP9 Proteine), TIMP1 (zeige TIMP1 Proteine), and NGAL (zeige LCN2 Proteine) (also MMP2 in 220 kDa complex) without proteolytic activity.

  2. Data demonstrate for the first time that MMP2 and MMP9 (zeige MMP9 Proteine) are expressed in swine ovarian follicle both in theca and granulosa layers.

  3. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (zeige MMP9 Proteine) and MMP-2, caspase-3 (zeige CASP3 Proteine) and BDNF (zeige BDNF Proteine)

  4. MMP-2 may play an important role in regulating MLC1 turnover in the heart under normal physiological conditions

  5. Oxygen for newborn resuscitation increases MMP-2/-9 activity resulting in tissue damage and influencing remodeling processes.

  6. PI3K-dependent regulation of MT1-MMP (zeige MMP14 Proteine) protein synthesis and subsequent activation of latent MMP-2 as critical events in neointimal hyperplasia after vascular injury.

  7. MMP-2 processes dental sialophosphoprotein into smaller subunits in the dentin matrix during odontogenesis

  8. contribution of MMPs to the inflammatory breakdown of the blood-CSF (zeige CSF2 Proteine) barrier in vitro

  9. The levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 (zeige MMP9 Proteine) in the corpus luteum of swine during luteolysis are reported.

  10. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (zeige VEGFA Proteine), pro-MMP-9 (zeige MMP9 Proteine), MMP-2, VEGFR-1 (zeige FLT1 Proteine), VEGFR-2 (zeige KDR Proteine), and TIMP-1 (zeige TIMP1 Proteine), which may contribute to the development of venous stenosis.

Rabbit Matrix Metalloproteinase 2 (MMP2) Interaktionspartner

  1. Inflammatory factors such as TNF-alpha (zeige TNF Proteine) can stimulate MMP-2/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases

  2. Results provide evidence that MMP-2 bears the potentiality to cleave alpha-DG enriched from rabbit skeletal muscle indicating that this degradation indeed might also occur in vivo.

  3. In conclusion, MMP-2 could be responsible for the proteolysis of dystrophin (zeige DMD Proteine).

  4. Castor oil polymer induces bone formation with high matrix metalloproteinase-2 expression.

  5. MMP2 spinal cord expression is increased in cervical spondylotic myelopathy.

  6. Ulinastatin (zeige AMBP Proteine) effectively inhibited the increased expression of MMP-2, MMP-3 (zeige MMP3 Proteine), and iNOS (zeige NOS2 Proteine) in degenerated NP cells induced by IL-1beta (zeige IL1B Proteine) in vitro.

  7. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2, MMP-9 (zeige MMP9 Proteine) and TIMP-1 (zeige TIMP1 Proteine) in rabbits with acute paraquat poisoning.

  8. The RNA interference targeting COX-2 can effectively inhibit the expression of COX-2 and MMP-2 in IL-1alpha stimulated rabbit corneal stromal cells in vitro.

  9. Our results strongly suggest that ischaemic postconditioning may exert part of its cardioprotective effects through the inhibition of MMP-2 activity.

MMP2 Protein Überblick

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MMP2

  • matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (MMP2)
  • Matrix metalloproteinase 2 (Mmp2)
  • matrix metalloproteinase 2 (mmp2)
  • matrix metalloproteinase-2 (mmp-2)
  • matrix metalloproteinase 2 (Mmp-2)
  • matrix metalloproteinase-2 (LOC100135793)
  • matrix metallopeptidase 2 (Mmp2)
  • 2-MMP Protein
  • anon-WO0118547.84 Protein
  • CG1794 Protein
  • CLG4 Protein
  • CLG4A Protein
  • dm-2MMP Protein
  • Dm2-MMP Protein
  • Dmel\\CG1794 Protein
  • dmmp2 Protein
  • fgmmp-2 Protein
  • GelA Protein
  • l(2)02353 Protein
  • LOC100135793 Protein
  • MMP-2 Protein
  • MMP-II Protein
  • mmp2 Protein
  • MONA Protein
  • TBE-1 Protein
  • wu:fa99h12 Protein
  • wu:fk89d01 Protein

Bezeichner auf Proteinebene für MMP2

CG1794-PB , CG1794-PC , CG1794-PD , Mmp2-PB , Mmp2-PC , Mmp2-PD , matrix metalloprotease 2 , matrix metalloproteinase , matrix metalloproteinase 2 , 72 kDa type IV collagenase , Gelatinase A , matrix metalloproteinase-2 , 72 kDa gelatinase , MMP-2 , gelatinase A , 72kD gelatinase , 72kD type IV collagenase , 72kDa gelatinase , 72kDa type IV collagenase , collagenase type IV-A , matrix metalloproteinase-II , neutrophil gelatinase , matrix metalloproteinase 2 (72 KDa type IV collagenase) , matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

100033948 Equus caballus
35997 Drosophila melanogaster
337179 Danio rerio
653022 Takifugu rubripes
657982 Tribolium castaneum
100135793 Oncorhynchus mykiss
81686 Rattus norvegicus
17390 Mus musculus
4313 Homo sapiens
282872 Bos taurus
386583 Gallus gallus
403733 Canis lupus familiaris
397391 Sus scrofa
100009000 Oryctolagus cuniculus
443115 Ovis aries
Ausgewählte Anbieter für MMP2 Proteine (MMP2)
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