CARD9 Proteine (CARD9)

Caspase Recruitment Domain Family, Member 9 Proteine (CARD9)
Auf finden Sie aktuell 10 Caspase Recruitment Domain Family, Member 9 (CARD9) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CARD9 Antikörper (73) und CARD9 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 89 CARD9 Produkte verfügbar.
CANDF2, card9, Gm782, hCARD9
alle Proteine anzeigen Gen GeneID UniProt
CARD9 332579  
CARD9 64170 Q9H257
CARD9 64171 Q9EPY0

Weitere Synonyme anzeigen

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Weitere Proteine zu CARD9 Interaktionspartnern

Mouse (Murine) Caspase Recruitment Domain Family, Member 9 (CARD9) Interaktionspartner

  1. this study shows that oxidized low-density lipoprotein immune complex priming of the Nlrp3 (zeige NLRP3 Proteine) inflammasome Is dependent on CARD9

  2. results demonstrate that Dectin-1 (zeige CLEC7A Proteine)-triggered Card9 signaling but not inflammasome activation can potently cross-prime Ag-specific cytotoxic T-cells, suggesting that this pathway would be a candidate for immunotherapy and vaccine development

  3. CARD9 promotes recovery from colitis by promoting interleukin (IL)-22 production, and Card9(-/-) mice are more susceptible to colitis. The microbiota from Card9(-/-) mice fails to metabolize tryptophan into metabolites that act as aryl hydrocarbon receptor (AHR) ligands.

  4. The findings suggest that CARD9 mediates the innate immune and Th17-mediated adaptive immune responses against dematiaceous fungal infections at the early stage of infection.

  5. CARD9 knockout alleviated HFD-induced insulin (zeige INS Proteine) resistance and glucose intolerance, prevented myocardial dysfunction with preserved cardiac fractional shortening and cardiomyocyte contractile properties. CARD9 knockout also significantly decreased the number of infiltrated macrophages in the heart with reduced myocardium-, plasma-, and macrophage-derived cytokines

  6. a possible role for the Syk (zeige SYK Proteine)-CARD9 pathway in DCs in excessive inflammation of IFV-infected lungs.

  7. CARD9 mediates necrotic smooth muscle cell-induced inflammation in macrophages contributing to neointima formation of vein grafts.

  8. Mincle (zeige CLEC4E Proteine) Activation and the Syk (zeige SYK Proteine)/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye

  9. CARD9 reduces viability specifically in males and promotes tumorigenesis specifically in the large intestines of these male mice.

  10. Ubiquitination of CARD9 by TRIM62 regulates CARD9-mediated anti-fungal immunity.

Human Caspase Recruitment Domain Family, Member 9 (CARD9) Interaktionspartner

  1. The IBD risk allele at CARD9 rs10781499 is associated with reduced aryl hydrocarbon activation by microbiota-derived metabolites extracted from fecal samples of IBD patients.

  2. Card9 in severe acute pancreatitis patients was overexpressed, suggesting the close correlation with the outcome and severity of pancreatic injury in patients.

  3. CARD9 allele C (p = 0.012) and genotype CC (p = 0.012) were significant protective factors against ankylosing spondylitis only in HLA-B27-negative patients.

  4. The findings linked, for the first time, mutations leading to CARD9 deficiencies with susceptibility to opportunistic filamentous fungi.

  5. Chronic and invasive fungal infections have been described in a Turkish consanguineous family with CARD9 deficiency.

  6. We observed no significant association between the investigated CARD9 SNPs and the susceptibility of either Crohn's disease or ulcerative colitis

  7. This study identified two novel independent loci (MAP3K14 (zeige MAP3K14 Proteine) and CARD9) strongly associated with joint damage in Mexican Americans and European Americans and a few shared loci showing suggestive evidence for association.

  8. Impaired RASGRF1 (zeige RASGRF1 Proteine)/ERK (zeige EPHB2 Proteine)-mediated GM-CSF (zeige CSF2 Proteine) response characterizes CARD9 deficiency in French-Canadians.

  9. our data highlight the critical role of CARD9-dependent neutrophil trafficking into the central nervous system

  10. A CARD9 variant (protective against inflammatory bowel disease)is C-terminally truncated and acts in a dominant-negative manner for CARD9-mediated cytokine production. K125 is the CARD9 ubiquitinated residue. Ubiquitination is needed for CARD9 activity.

CARD9 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.

Alternative names and synonyms associated with CARD9

  • caspase recruitment domain family, member 9 (Card9)
  • caspase recruitment domain family, member 9 (CARD9)
  • Caspase recruitment domain-containing protein 9 (card9)
  • caspase recruitment domain family, member 9 (card9)
  • CANDF2 Protein
  • card9 Protein
  • Gm782 Protein
  • hCARD9 Protein

Bezeichner auf Proteinebene für CARD9

caspase recruitment domain-containing protein 9 , Caspase recruitment domain-containing protein 9 , caspase recruitment domain family, member 9 , caspase recruitment domain protein 9 , caspase recruitment domain-containing protein 9-like , rCARD9

332579 Mus musculus
100068666 Equus caballus
100195248 Salmo salar
427756 Gallus gallus
464917 Pan troglodytes
768054 Bos taurus
100145327 Xenopus (Silurana) tropicalis
100447342 Pongo abelii
100484878 Ailuropoda melanoleuca
100020522 Monodelphis domestica
100585473 Nomascus leucogenys
64170 Homo sapiens
64171 Rattus norvegicus
607492 Canis lupus familiaris
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