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Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. Zusätzlich bieten wir Ihnen alpha 2 Macroglobulin Antikörper (303) und alpha 2 Macroglobulin Proteine (40) und viele weitere Produktgruppen zu diesem Protein an.
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Human alpha 2 Macroglobulin ELISA Kit für Competition ELISA - ABIN2683306
Pineda-Salgado, Craig, Blank, Kessler: Expression of Panza, an alpha2-macroglobulin, in a restricted dorsal domain of the primitive gut in Xenopus laevis. in Gene expression patterns : GEP 2005
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Human alpha 2 Macroglobulin ELISA Kit für Sandwich ELISA - ABIN1874321
Lee, Cho, Kim, Kang, Yoo, Chang, Ko, Kim: Semi-quantitative measurement of a specific glycoform using a DNA-tagged antibody and lectin affinity chromatography for glyco-biomarker development. in Molecular & cellular proteomics : MCP 2015
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Human alpha 2 Macroglobulin ELISA Kit für Sandwich ELISA - ABIN2683305
Tasnim, Zink: Cross talk between primary human renal tubular cells and endothelial cells in cocultures. in American journal of physiology. Renal physiology 2012
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Mouse (Murine) alpha 2 Macroglobulin ELISA Kit für Sandwich ELISA - ABIN2683308
Jensen, Humle Jørgensen, Datta, Sørensen: Significantly increased fractions of transformed to total alpha2-macroglobulin concentrations in plasma from patients with multiple sclerosis. in Biochimica et biophysica acta 2004
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Human alpha 2 Macroglobulin ELISA Kit für Competition ELISA - ABIN366856
Xu, Zhang, Luo, Zhou, Wang, Fang, Li, Mu, Zhang, Zhang, Xie: Comparative proteomic analysis of plasma from major depressive patients: identification of proteins associated with lipid metabolism and immunoregulation. in The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012
Proteomics study showed a strong association of FN1, A2M, C4BPA and CFB in molecular subtypes of breast cancer, in which, C4BPA and A2M demonstrated a potent signature in blood plasma and tissue samples of Luminal-B (LB) and Triple-negative (TN)subtypes in BC patients, respectively.
BBB (zeige ALMS1 ELISA Kits) disruption is present in ACS (zeige PLA2G15 ELISA Kits), and elevated levels of IL-6 (zeige IL6 ELISA Kits) and C3 in CSF (zeige CSF2 ELISA Kits) in diffuse NPSLE
Case Reports: inflammatory myofibroblastic tumors of the lung containing a chimeric A2M-ALK (zeige ALK ELISA Kits) gene categorized as a specific type of inflammatory myofibroblastic tumor that develops exclusively in neonates and infants.
The plasma level of alpha2M was found positively correlated, while HCII (zeige SERPIND1 ELISA Kits) level was negatively correlated with higher vulnerability of carotid plaques. Both proteins were efficient in differentiating stable and vulnerable carotid plaques. These provide potential new targets for the research of carotid plaque vulnerability. Plasma alpha2M and HCII (zeige SERPIND1 ELISA Kits) may be potential biomarkers for evaluation of the vulnerability of carotid ...
Stabilizers during pasteurization improved alpha-2-macroglobulin (alpha2-M) activity by more than 300% points compared with the unstabilized control.
Data show that low that low globulin (GLB (zeige DCXR ELISA Kits)) levels were significantly associated with favorable survival, and low ALB (zeige ALB ELISA Kits) levels were associated with a significantly worse survival .
This work demonstrates that alpha2M*/CS-GRP78 (zeige HSPA5 ELISA Kits) acts as an upstream regulator of the PDK1 (zeige PDK1 ELISA Kits)/PLK1 (zeige PLK1 ELISA Kits) signaling axis to modulate c-MYC (zeige MYC ELISA Kits) transcription and its target genes, suggesting a therapeutic strategy for targeting c-MYC (zeige MYC ELISA Kits)-associated malignant progression.
Meta-analysis. Our data indicate that the rs669 (A/G) polymorphisms in A2M gene are associated with increased risk in Parkinson disease.
These data demonstrate that alpha2M* and LRP1 (zeige LRP1 ELISA Kits) modulate the BKCachannel in human myometrium and that BKCaand its immunomodulatory interacting partners regulate Ca(2 (zeige CA2 ELISA Kits)+)dynamics in hMSMCs during pregnancy.
we identify a single serum factor, alpha2-macroglobulin (alpha2M), which is both required and sufficient for rosetting mediated by the parasite protein P. falciparum erythrocyte membrane protein 1 protein HB3VAR06 and some other rosette-mediating PfEMP1 proteins
A model is proposed that suggests that unlike proteases, which are irreversibly bound to activated alpha2M, hepcidin (zeige HAMP ELISA Kits) remains labile and available to down-regulate Fpn1 (zeige SLC40A1 ELISA Kits).
Data show that MAA-A2M adduct formation abrogated the binding of A2M bait region with TGF-beta1, trypsin, and elastase.
MMP9 (zeige MMP9 ELISA Kits) production promoted by the alpha(2)M*/LRP1 (zeige LRP1 ELISA Kits) interaction required the activation of both MAPK (zeige MAPK1 ELISA Kits)-ERK1/2 (zeige MAPK1/3 ELISA Kits) and NF-kappaB (zeige NFKB1 ELISA Kits) signaling pathways.
Alpha2 macroglobulin requires cyclic amp (zeige TMPRSS5 ELISA Kits) and signal transduction for cell growth
Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin.
the 4622-base pair cDNA encodes a protein of 1473 AA with >70% sequence identity and all typical domains of other A2M-family members in humans and rodents
Data describe the role of the PI3-kinase (zeige PIK3CA ELISA Kits)/PDK (zeige PDK2 ELISA Kits)/Akt (zeige AKT1 ELISA Kits)/p70s6k (zeige RPS6KB1 ELISA Kits) signaling cascade in alpha 2-macroglobulin-induced cellular proliferation and the role of CREB (zeige CREB1 ELISA Kits) in these events.
review the A2M gene families of mice and humans, the predicted structural relationships between A2M and its pregnancy induced forms and the postulated roles for this gene family in normal pregnancy.
the inhibition of proteases on the surface of microorganisms by an ancestral alpha2M-like thiol ester protein may generate "arrays" of oligomannose glycans to which MBL or other lectins can bind
PDGF (zeige PDGFA ELISA Kits)-BB and TGF-beta1 (zeige TGFB1 ELISA Kits) binding to intact alpha2M is specific, involving a defined region of the alpha2M subunit
Data suggest that alpha(2)-macroglobulin from serum could significantly compensate for the impaired cumulus expansion of oocytes matured in serum.
Mutations in the promoter region and the 3'-untranslated region of the A2M gene are involved in the mastitis susceptibility in dairy cows.
We report here for the first time the direct isolation of Spp24 (zeige SPP2 ELISA Kits) covalently bound to alpha2-macroglobulins as a core complex (Spp24 (zeige SPP2 ELISA Kits)-alpha2M) from bovine calf serum.
Exon 29 c.3535A>T in the alpha-2-macroglobulin gene causing aberrant splice variants is associated with mastitis.
These results suggest the possible involvement of cathepsin E (zeige CTSE ELISA Kits) in disruption of the structural and functional integrity of alpha 2-macroglobulin in the endolysosome system.
Alpha2-macroglobulin is a substrate and an endogenous inhibitor for ADAMTS-4 (zeige ADAMTS4 ELISA Kits) and ADAMTS-5 (zeige ADAMTS5 ELISA Kits)
Amounts of alpha(2)-M receptor in granulosa cells were strongly inversely associated with concentrations of estradiol in dominant and subordinate follicles.
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
, ovomacroglobulin, ovostatin
, alpha 2m
, alpha-2-macroglobulin b
, pregnancy zone protein