Zinc Finger and BTB Domain Containing 7A Proteine (ZBTB7A)

acts as a transcriptional repressor\; may play a role in osteoclastogenesis [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen ZBTB7A Antikörper (112) und ZBTB7A Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ZBTB7A 51341 O95365
Maus ZBTB7A ZBTB7A 16969 O88939
ZBTB7A 117107 Q9QZ48
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.458,89 €
Details

ZBTB7A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Rat (Rattus)

Weitere Proteine zu Zinc Finger and BTB Domain Containing 7A (ZBTB7A) Interaktionspartnern

Human Zinc Finger and BTB Domain Containing 7A (ZBTB7A) Interaktionspartner

  1. Mutation in ZBTB7A is associated with core-binding factor (zeige CBFB Proteine) acute myeloid leukemia (zeige BCL11A Proteine).

  2. Zbtb7a knockdown by siRNA suppressed cell proliferation and i (zeige MLXIP Proteine)nduced G1 cell cycle arrest and apoptosis (zeige MLXIP Proteine) in lung cancer cells. Furthermore, miR-125a expression showed a negative correlation with Zbtb7a expression in non-small cell lung cancer tissues.

  3. Data suggest that microRNA miR (zeige MLXIP Proteine)-520e directly targets to the 3'-untranslated region (3'-UTR) of zinc finger and BTB domain containing 7A protein (Zbtb7a).

  4. CCAT2 promotes tumorigenesis by over-expression of Pokemon.

  5. High FBI-1 expression is associated with hepatocellular carcinoma.

  6. there is an auto-regulatory circuit consisting of miR (zeige MLXIP Proteine)-125 and Pokemon, which promotes the progression of HCC (zeige FAM126A Proteine) and may be a promising therapeutic target in clinical HCC (zeige FAM126A Proteine) treatment

  7. Pokemon was found to enhance the migration and invasion of hepatocellular carcinoma by increasing MEF2D (zeige MEF2D Proteine) expression

  8. Pokemon was significantly downregulated in OSCC.

  9. ZBTB7A directly binds to the promoter and transcriptionally represses the expression of MCAM (zeige MCAM Proteine), establishing ZBTB7A as a bona fide transcriptional repressor of MCAM (zeige MCAM Proteine)

  10. MEF2D (zeige MEF2D Proteine) was also found to increase the transcription of Pokemon by binding myocyte enhancer factor 2 (MEF2 (zeige MEF2A Proteine)) sites within its promoter region, that can promote Hepatocellular carcinoma invasion

Mouse (Murine) Zinc Finger and BTB Domain Containing 7A (ZBTB7A) Interaktionspartner

  1. This study identified Zbtb7a as a novel direct target for miR (zeige MLXIP Proteine)-125a by gene expression profiling in miR (zeige MLXIP Proteine)-125a knockout mice combined with bioinformatics target prediction, and elucidated the role of Zbtb7a in oncogenesis.

  2. This study demonstrated an unexpected transcription-independent function for LRF in the classical non-homologous end joining pathway of double-strand break repair.

  3. LRF short hairpin RNA suppressed the expression of LRF protein in a glioma cell line compared to the negative control vector-transfected glioma cells. LRF knockdown also reduced cell viability and enhanced cisplatin-induced apoptosis in glioma cells.

  4. Data indicate that transcription factors Thpok (zeige ZBTB7B Proteine) and LRF redundantly maintain CD4 (zeige CD4 Proteine)+ lineage integrity.

  5. Findings demonstrate that Pokemon suppresses Sprouty1 expression through a miR (zeige MLXIP Proteine)-21-mediated mechanism, affecting the growth and proliferation of liver cancer cells.

  6. Data show that Notch1 (zeige NOTCH1 Proteine)/Dll4 (zeige DLL4 Proteine)-mediated T-cell instructive signals to long-term HSCs (LT-HSCs) are suppressed by Lrf expression in the bone marrow microenvironment.

  7. These results support a critical role for LRF in transcriptional control of differentiation in oligodendrocyte lineage cells during developmental myelination in the CNS.

  8. T cells lacking Thpok (zeige ZBTB7B Proteine), which only displayed LRF-dependent functions, contributed to multiple effector responses, both in vitro and in vivo, with the notable exception of Th2 cell responses that control extracellular parasites

  9. study shows that LRF plays stage-specific distinct roles in osteoclast differentiation, exemplifying the delicate transcriptional regulation at work in lineage commitment

  10. Data demonstrate that the transcription factor leukemia/lymphoma-related factor (LRF) forms an obligate dimer in B cells and regulates mature B cell lineage fate and humoral immune responses via distinctive mechanisms.

ZBTB7A Protein Überblick

Protein Überblick

acts as a transcriptional repressor\; may play a role in osteoclastogenesis

Genbezeichner und Symbole assoziert mit ZBTB7A

  • zinc finger and BTB domain containing 7A (ZBTB7A)
  • similar to zinc finger and BTB domain containing 36 (ZBTB7A)
  • zinc finger and BTB domain containing 7a (Zbtb7a)
  • 9030619K07Rik Protein
  • 9130006G12Rik Protein
  • AI452336 Protein
  • FBI-1 Protein
  • FBI1 Protein
  • Lrf Protein
  • OCZF Protein
  • Pokemon Protein
  • Zbtb7 Protein
  • ZBTB7A Protein
  • ZNF857A Protein

Bezeichner auf Proteinebene für ZBTB7A

zinc finger and BTB domain containing 7A , similar to zinc finger and BTB domain containing 36 , HIV-1 1st-binding protein 1 , HIV-1 inducer of short transcripts binding protein , POK erythroid myeloid ontogenic factor , POZ and Krueppel erythroid myeloid ontogenic factor , TIP21 , TTF-I-interacting peptide 21 , factor binding IST protein 1 , factor that binds to inducer of short transcripts protein 1 , leukemia/lymphoma-related factor , lymphoma related factor , zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein , zinc finger and BTB domain-containing protein 7A , zinc finger protein 857A , leukemia/lymphoma related factor , osteoclast-derived zinc finger protein , cLRF , leukemia/lymphoma related factor cLRF

GENE ID SPEZIES
468671 Pan troglodytes
705033 Macaca mulatta
51341 Homo sapiens
16969 Mus musculus
485048 Canis lupus familiaris
788491 Bos taurus
117107 Rattus norvegicus
395411 Gallus gallus
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