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Tryptase alpha/beta 1 Proteine (TPSAB1)

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Zusätzlich bieten wir Ihnen Tryptase alpha/beta 1 Antikörper (104) und Tryptase alpha/beta 1 Kits (61) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TPSAB1 7177 Q15661 , P20231
TPSAB1 54271 P27435
TPSAB1 100503895 Q02844
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Showing 10 out of 33 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
685,71 €
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HOST_Escherichia coli (E. coli) Wildschwein His tag,GST tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
713,33 €
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HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
716,19 €
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HOST_Escherichia coli (E. coli) Hund His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
740,95 €
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HOST_Mammalian Cells Human His tag   10 μg Anmelden zum Anzeigen 8 bis 9 Tage
231,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.500,31 €
Details

TPSAB1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
,
Rat (Rattus) ,

Mouse (Murine) ,

Am meisten referenzierte Tryptase alpha/beta 1 Proteine

  1. Human TPSAB1 Protein expressed in Escherichia coli (E. coli) - ABIN1098685 : Marquardt, Zettl, Huber, Bode, Sommerhoff: The crystal structure of human alpha1-tryptase reveals a blocked substrate-binding region. in Journal of molecular biology 2002 (PubMed)
    Zeige alle 2 Referenzen für ABIN1098685

Weitere Proteine zu Tryptase alpha/beta 1 (TPSAB1) Interaktionspartnern

Human Tryptase alpha/beta 1 (TPSAB1) Interaktionspartner

  1. CD3 (zeige CD3 Proteine) showed a positive correlation with tryptase and microvascular density, while multiple regression analysis efficaciously predicted microvascular density depending on CD3 (zeige CD3 Proteine) and tryptase as predictors, supporting a complex interplay between these cells in sustaining tumor angiogenesis in Diffuse large B cell lymphoma patients.

  2. We found the determination of serum tryptase levels over time to be a reassuring correlate of clinical improvement in pediatric mastocytosis

  3. Elevated serum tryptase and ET-1 may be markers of increased coronary instability; some cytokines may be related to the extension of CAD.

  4. these data suggest that the expression of tryptase is regulated by SCF (zeige KITLG Proteine)/C-KIT signaling via the ERK1/2 and p38MAPK (zeige MAPK14 Proteine) pathways.

  5. Urine tryptase beta was increased in patients with chronic prostatitis/chronic pelvic pain syndrome compared to controls.

  6. Results demonstrated serum tryptase levels in colo-rectal cancer (CRC (zeige CALR Proteine)) patients before radical surgical resection.

  7. Circulating tryptase level is associated to obesity related parameters and has a close relation with various metabolic risk factors for subclinical atherosclerosis

  8. Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma.

  9. The best criterion for discriminating IgE- and non IgE-mediated hypersensitivity reactions in anaesthesia was a tryptase value exceeding twice the basal one.

  10. With elevated tryptase level, a history of hornet sting-triggered anaphylaxis, and venom-specific IgE, a patient is at increased risk of severe life-threatening anaphylactic response to a future sting, as well as for having underlying clonal mastocytosis.

Mouse (Murine) Tryptase alpha/beta 1 (TPSAB1) Interaktionspartner

  1. Following TNFalpha (zeige TNF Proteine) treatment, increased elastase and tryptase modify the balance between activation and deactivation, elevating active chemerin (zeige RARRES2 Proteine) concentration in adipocyte media and subsequent CMKLR1 (zeige CMKLR1 Proteine) activation.

  2. transcriptional activation of mouse mast cell Protease-7 by activin and transforming growth factor-beta is inhibited by microphthalmia-associated transcription factor (zeige MITF Proteine)

  3. Because mMCP-6 and mMCP-7 can compensate for each other in this mouse disease model, the elimination of both tryptases is necessary to reveal the prominent roles of these serine proteases in joint inflammation and destruction.

  4. TGF-beta stimulates mmcp-7 transcription through the Smad3-Smad4 pathway as well as c-fos induction

Tryptase alpha/beta 1 (TPSAB1) Protein Überblick

Protein Überblick

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells\; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Genbezeichner und Symbole assoziert mit Tryptase alpha/beta 1 Proteine (TPSAB1)

  • tryptase alpha/beta 1 (tpsab1)
  • tryptase (MCT7)
  • tryptase (LOC100049001)
  • tryptase (TRYPTASE-1)
  • tryptase alpha/beta 1 (TPSAB1)
  • tryptase alpha/beta 1 (Tpsab1)
  • tryptase-2 (LOC100144429)
  • tryptase-like (LOC100146737)
  • Mcp-7 Protein
  • Mcp7 Protein
  • Mcpt7 Protein
  • MMCP-7 Protein
  • PMCT7 Protein
  • rMCP-7 Protein
  • TPS1 Protein
  • TPS2 Protein
  • tpsab1 Protein
  • TPSB1 Protein

Bezeichner auf Proteinebene für Tryptase alpha/beta 1 Proteine (TPSAB1)

tryptase alpha/beta 1 , mast cell alpha II tryptase , mast cell beta I tryptase , tryptase I , tryptase alpha II , tryptase alpha-1 , tryptase alpha/beta-1 , tryptase beta 1 , tryptase beta I , tryptase beta-1 , tryptase-1 , tryptase-I , tryptase-III , MMCP-7 , mast cell protease 7 , tryptase , tryptase, skin , mast cell-restricted serine protease 7

GENE ID SPEZIES
497002 Xenopus (Silurana) tropicalis
397389 Sus scrofa
100049001 Canis lupus familiaris
443433 Ovis aries
7177 Homo sapiens
54271 Rattus norvegicus
100503895 Mus musculus
100144429 Ovis aries
100146737 Equus caballus
Ausgewählte Anbieter für Tryptase alpha/beta 1 Proteine (TPSAB1)
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