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Tropomodulin 1 Proteine (TMOD1)

TMOD1 encodes a member of the tropomodulin family. Zusätzlich bieten wir Ihnen Tropomodulin 1 Antikörper (63) und Tropomodulin 1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TMOD1 7111 P28289
TMOD1 21916 P49813
TMOD1 25566  
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Showing 8 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
518,10 €
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.837,30 €
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.837,30 €
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
700,60 €

TMOD1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Tropomodulin 1 (TMOD1) Interaktionspartnern

Human Tropomodulin 1 (TMOD1) Interaktionspartner

  1. The mutation reduced binding affinity for both Lmod2 (zeige LMOD2 Proteine) and Tmod1. The effect of the K15N mutation on Tpm1.1 binding to Lmod2 (zeige LMOD2 Proteine) and Tmod1 provides a molecular rationale for the development of familial dilated cardiomyopathies .

  2. Study highlighted a novel TMOD1-mediated link between NF-kappaB (zeige NFKB1 Proteine) activation and MMP13 (zeige MMP13 Proteine) induction, which accounts in part for the NF-kappaB (zeige NFKB1 Proteine)-dependent malignant phenotype of TNBC.

  3. Tmod1 and Tmod3 (zeige TMOD3 Proteine) showed somewhat different tropomyosin (zeige TPM2 Proteine)-binding site utilization.

  4. The structures and biochemical analysis of structure-inspired mutants showed that one Tmod molecule interacts with three actin subunits at the pointed end, while also contacting two tropomyosin (zeige TPM2 Proteine) molecules on each side of the filament.

  5. Tropomyosin (zeige TPM2 Proteine) requires an intact N-terminal coiled coil to interact with this protein

  6. levels of TM1 (zeige TPM2 Proteine), TM2 (zeige TPM2 Proteine) and TM3 (zeige TPM1 Proteine) are reduced in human transitional cell carcinoma cells, but significantly upregulated by inhibition of the mitogen-activated protein kinase (zeige MAPK1 Proteine)-signaling pathway

  7. The N-terminal "KRK ring" may participate in balancing electrostatic force with hydrophobic interaction in dimerization of TM and its binding to E-Tmod.

  8. study identifies several amino acid residues on Tmod-1 that are important for its interaction with TM5 (a nonmuscle TM isoform)

Mouse (Murine) Tropomodulin 1 (TMOD1) Interaktionspartner

  1. distinct F-actin organizations are present in small protrusions versus large paddles. Formation and/or maintenance of large paddle domains depends on a beta2-spectrin-actin network stabilized by Tmod1. alpha-Actinin (zeige ACTN1 Proteine)-crosslinked F-actin bundles are enhanced in absence of Tmod1, indicating altered cytoskeleton organization.

  2. TMOD1 expression was upregulated significantly (p<0.05) in OSCC.

  3. RNAi depletion of Tmod1 from either wild-type or Tmod4 (zeige TMOD4 Proteine)(-/-) muscle fibers leads to thin filament elongation by approximately 15%.

  4. The C-terminal extension of Lmod2 (zeige LMOD2 Proteine) and C terminal of Tmod1 are sufficient to produce a filament nucleator.

  5. Calpain-mediated proteolysis of tropomodulin isoforms TMOD1 and TMOD4 (zeige TMOD4 Proteine) leads to thin filament elongation in dystrophic skeletal muscle.

  6. Role of Tmod1 protein's leucine rich repeat domain in the formation of neurite-like processes

  7. Tmod1 is involved in a functional synergy critical for regulating lens fiber cell geometry, transparency, and mechanical stiffness.

  8. Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex.

  9. The Tmod1 deletion caused Tmod3 to leave its SR compartment, leading to mislocalization and destabilization of the Tmod3-gamma(cyto)-actin-sAnk1.5 complex.

  10. Tmod1-null mice display a mild anemia with features resembling hereditary spherocytic elliptocytosis.

Tropomodulin 1 (TMOD1) Protein Überblick

Protein Überblick

This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit Tropomodulin 1 Proteine (TMOD1)

  • tropomodulin 1 (TMOD1)
  • tropomodulin 1 (tmod1)
  • tropomodulin 1 (Tmod1)
  • D9S57E Protein
  • E-Tmod Protein
  • ETMOD Protein
  • si:ch211-288h2.6 Protein
  • Tmod Protein
  • TMOD1 Protein
  • tropomodulin-1 Protein

Bezeichner auf Proteinebene für Tropomodulin 1 Proteine (TMOD1)

tropomodulin-1 , tropomodulin 1 , tropomodulin-1-like , E-Tmod , e-tropomodulin , erythrocyte tropomodulin , E-Tropomodulin

395883 Gallus gallus
464599 Pan troglodytes
474771 Canis lupus familiaris
715838 Macaca mulatta
100149766 Danio rerio
100316850 Sus scrofa
100397199 Callithrix jacchus
100443166 Pongo abelii
100588809 Nomascus leucogenys
7111 Homo sapiens
21916 Mus musculus
25566 Rattus norvegicus
780784 Bos taurus
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