Rhotekin Proteine (RTKN)

RTKN encodes a scaffold protein that interacts with GTP-bound Rho proteins. Zusätzlich bieten wir Ihnen Rhotekin Antikörper (39) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RTKN 6242 Q9BST9
RTKN 20166 Q8C6B2
RTKN 297383 Q6V7V2
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Top Rhotekin Proteine auf antikoerper-online.de

Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.397,78 €
HOST_Escherichia coli (E. coli) Ratte T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
640,00 €
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
304,76 €

RTKN Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus) ,

Weitere Proteine zu Rhotekin (RTKN) Interaktionspartnern

Human Rhotekin (RTKN) Interaktionspartner

  1. Let-7a microRNA inhibits tumor cell growth and metastasis by directly targeting RTKN in human colon cancer.

  2. RTKN is upregulated in hepatocellular carcinoma.MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma.

  3. The RTKN protein is associated with lung cancer in clinic samples and exerts anticancer activity in lung adenocarcinoma cells through inhibiting cell cycle progression and the DNA replication machinery.

  4. RTKN could affect the proliferation and metastasis of colon cancer by reducing expression of MCM2 (zeige MCM2 Proteine)/3/5, CDK1 (zeige CDK1 Proteine)/2 and PCNA (zeige PCNA Proteine)

  5. suggest that interaction of S100A4 (zeige S100A4 Proteine) and Rhotekin permits S100A4 (zeige S100A4 Proteine) to complex with RhoA (zeige RHOA Proteine) and switch Rho function from stress fiber formation to membrane ruffling to confer an invasive phenotypea

  6. Protein kinase D (zeige PRKD1 Proteine) regulates RhoA (zeige RHOA Proteine) activity via phosphorylation rhotekin at Ser (zeige SIGLEC1 Proteine)-435.

  7. Rho/RTKN-mediated NF-kappaB (zeige NFKB1 Proteine) activation leading to cell survival may play a key role in gastric tumorigenesis.

  8. These results suggest that the RTKN gene is involved in bladder carcinogenesis and progression in bladder carcinoma, indicating that RTKN gene could be a molecular target in cancer therapy.

  9. Lin-7B is a binding partner for Rhotekin in the human brain cDNA library

  10. SEPT9 (zeige SEPT9 Proteine) sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4 (zeige SEPT4 Proteine)/SEPT11 (zeige SEPT11 Proteine) and resistance to Rho/Rhotekin-signaling

Mouse (Murine) Rhotekin (RTKN) Interaktionspartner

  1. these findings suggest that cGK (zeige PRKG1 Proteine)-Ialpha interacts with and phosphorylates rhotekin, thereby contributing to neurite outgrowth regulation.

Rhotekin (RTKN) Protein Überblick

Protein Überblick

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit Rhotekin Proteine (RTKN)

  • rhotekin (RTKN)
  • rhotekin (rtkn)
  • rhotekin (Rtkn)
  • RTKN Protein

Bezeichner auf Proteinebene für Rhotekin Proteine (RTKN)

rhotekin , rhotekin-like

459334 Pan troglodytes
100053888 Equus caballus
100124981 Xenopus (Silurana) tropicalis
100349385 Oryctolagus cuniculus
100400941 Callithrix jacchus
100455723 Pongo abelii
100474465 Ailuropoda melanoleuca
100519086 Sus scrofa
6242 Homo sapiens
20166 Mus musculus
297383 Rattus norvegicus
475788 Canis lupus familiaris
539691 Bos taurus
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