anti-Prostaglandin E Synthase (PTGES) Antikörper

The protein encoded by PTGES is a glutathione-dependent prostaglandin E synthase. Zusätzlich bieten wir Ihnen Prostaglandin E Synthase Kits (22) und Prostaglandin E Synthase Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTGES 9536 O14684
PTGES 64292 Q9JM51
PTGES 59103  
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Top anti-Prostaglandin E Synthase Antikörper auf

Showing 10 out of 58 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p) Anti-PTGES antibody  ABIN1049251 IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Western Blot: Prostaglandin E Synthase Antibody [NBP1-87852] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert IHC (p) Testis Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [ABIN2581217] - Analysis of anti-PGES / PTGES antibody with human testis at concentration 10 ug/ml. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
Huhn Kaninchen Unkonjugiert IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with PTGES antibody ABIN213597 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Huhn Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [ABIN43477838] - Analysis of anti-PTGES antibody with human testis at 10 ug/ml. 0.05 mg Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human bladder carcinoma labeled with Rabbit Anti PTGEs Polyclonal Antibody, Unconjugated (ABIN735788) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
Human Kaninchen Unkonjugiert IHC (p) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Huhn Kaninchen Unkonjugiert IHC 0.05 mg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage

PTGES Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine) , ,

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Rat (Rattus) , , ,

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Am meisten referenzierte anti-Prostaglandin E Synthase Antikörper

  1. Human Polyclonal Prostaglandin E Synthase Primary Antibody für IHC, IHC (p) - ABIN4347784 : Camacho, Dilmé, Solà-Villà, Rodríguez, Bellmunt, Siguero, Alcolea, Romero, Escudero, Martínez-González, Vila: Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm. in Journal of lipid research 2013 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal Prostaglandin E Synthase Primary Antibody für IHC (p), WB - ABIN537285 : Nakanishi, Menoret, Tanaka, Miyamoto, Montrose, Vella, Rosenberg: Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity. in Cancer prevention research (Philadelphia, Pa.) 2011 (PubMed)

Weitere Antikörper gegen Prostaglandin E Synthase Interaktionspartner

Human Prostaglandin E Synthase (PTGES) Interaktionspartner

  1. COX-2 (zeige COX2 Antikörper) and mPGES-1-dependent synthesis of PGE2 contributes to a dedifferentiated aortic smooth muscle cell phenotype.

  2. Several studies provide evidence that the expression of mPGES1 is regulated by a number of transcriptional factors and inducible in conditions of inflammation and hypoxia.[review]

  3. The Genome Wide Area Study, using a phenotyping algorithm for asthma for data mining electronic medical records, identified four asthma susceptibility loci: 6p21.31, 9p21.2, and 10q21.3 in the European American population; and the prostaglandin synthase E gene (PTGES) at 9q34.11 in African Americans. Biologic support exists for genes at the 9p21.2 and 9q34.11 loci TEK (zeige TEK Antikörper), encoding the endothelial tyrosine in animal studies.

  4. C-myc (zeige MYC Antikörper) regulates mPGES1 expression by binding to the proximal promoter. C-myc (zeige MYC Antikörper) transfection in HeLa cells up-regulates mPGES1 mRNA and protein expression.

  5. COX-2 (zeige COX2 Antikörper) and mPGES-1 have roles in arachidonic acid regulation of inflammatory prostaglandin E2 biosynthesis

  6. The identified amino acid residues can act as target sites for the design and development of drug candidates against mPGES-1

  7. These findings support the value of a prognostic and predictive role for mPGES1.

  8. Data show that statins limit hepatic myofibroblasts proliferation via a cyclooxyegnase-2 (COX-2 (zeige COX2 Antikörper)) and microsomal PGE (zeige LIPF Antikörper) synthase-1 (mPGES-1) dependent pathway.

  9. Data show that cyclooxygenase2 (COX2 (zeige COX2 Antikörper))overexpression induces prostaglandin E synthase (PTGES) through early growth response 1 (EGR1 (zeige EGR1 Antikörper)) in colorectal cancer cell lines.

  10. mPGES-1 is downregulated via EGR1 (zeige EGR1 Antikörper) and has a role in caffeine inhibition on PGE2 synthesis of HBx hepatocytes

Mouse (Murine) Prostaglandin E Synthase (PTGES) Interaktionspartner

  1. that mPGES-1 exerts a potentially protective effect against renal fibrosis and inflammation induced by unilateral ureteral obstruction in mice

  2. In line with the acetyltransferase activity of p300 (zeige NOTCH1 Antikörper), H3K27 acetylation was reduced after HDACi and resulted in the formation of heterochromatin in the PTGES1 gene. In conclusion, HDAC (zeige HDAC3 Antikörper) activity maintains PTGES1 expression by recruiting p300 (zeige NOTCH1 Antikörper) to its gene

  3. The findings suggest that COX-2 (zeige COX2 Antikörper)/mPGES-1/PGE2 axis could be activated by albumin (zeige ALB Antikörper) in the proximal tubular cells via a NLRP3 (zeige NLRP3 Antikörper) inflammasome-mediated mechanism and could thus contribute to proteinuria-related renal tubular cell injury.

  4. mPGES-1 overexpression prevents Fas (zeige FAS Antikörper)-induced hepatocyte apoptosis and liver injury through activation of Akt (zeige AKT1 Antikörper) .

  5. The expression of Lcn2 (zeige LCN2 Antikörper) and mPGES-1 is strongly stimulated by lipopolysaccharide (LPS (zeige TLR4 Antikörper)), indicating that Lcn2 (zeige LCN2 Antikörper) mediates LPS (zeige TLR4 Antikörper)-induced inflammation. These findings shed light on the role of Lcn2 (zeige LCN2 Antikörper) during decidualization.

  6. The results show that mPges-1 may be a direct downstream target gene of the P4 receptor (zeige PGR Antikörper).

  7. mPges-1 depletion modestly increased thrombogenesis in LDL-receptor (zeige LDLR Antikörper) knockout mice. This response was markedly further augmented by coincident deletion of the I prostanoid receptor.

  8. Data (including data from studies in knockout mice) suggest interactions of cholinergic/prostaglandin systems participate in neuroimmunomodulation; microsomal Ptges-1 is part of cholinergic anti-inflammatory response in chronic inflammatory diseases.

  9. Prostacyclin synthase (zeige PTGIS Antikörper) and prostaglandin E synthase-1 cooperatively exacerbate inflammatory reactions but have opposing effects on carcinogenesis.

  10. Gas6 (zeige GAS6 Antikörper), through upregulation of Ptges/PGE2, contributes to cancer-induced venous thrombosis.

Cow (Bovine) Prostaglandin E Synthase (PTGES) Interaktionspartner

  1. The objective of this study was to evaluate the mRNA expression of prostaglandin-endoperoxide synthase 2 (PTGS 2 (zeige PTGS2 Antikörper)), prostaglandin F2alpha synthase (PTGFS) and prostaglandin E2 microsomal synthase 1 (mPTGES 1) in the endometrium of repeat-breeding cows with and without subclinical endometritis.

  2. Prostaglandin E synthase interacts with inducible heat shock protein 70 (zeige HSPA1A Antikörper) after heat stress in bovine primary dermal fibroblast cells.

  3. Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF (zeige TNF Antikörper)) and Fas (zeige FAS Antikörper) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.

  4. Data suggest that elevated temperatures stimulate PGE2 production in ampullary oviduct by increasing expression of PGES and HSP90AA1 (zeige HSP90AA1 Antikörper) (heat shock 90 kD protein 1 alpha).

  5. PGES pathway is responsible for the endometrial production of PGE (zeige LIPF Antikörper)(2) in the bovine endometrium during the estrous cycle

Horse (Equine) Prostaglandin E Synthase (PTGES) Interaktionspartner

  1. This study showed that COX-1 (zeige PTGS1 Antikörper) and COX-2 (zeige PTGS2 Antikörper) in genital carcinomas in the horse is poor; microsomal PGES-1 is more prominently expressed.

Prostaglandin E Synthase (PTGES) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Genbezeichner und Symbole assoziert mit PTGES

  • prostaglandin E synthase (PTGES) Antikörper
  • prostaglandin E synthase S homeolog (ptges.S) Antikörper
  • prostaglandin E synthase (Ptges) Antikörper
  • 2410099E23Rik Antikörper
  • D2Ertd369e Antikörper
  • MGC80290 Antikörper
  • MGST-IV Antikörper
  • MGST1-L1 Antikörper
  • MGST1L1 Antikörper
  • mPGES Antikörper
  • MPGES-1 Antikörper
  • Pges Antikörper
  • PIG12 Antikörper
  • PP102 Antikörper
  • PP1294 Antikörper
  • PTGES Antikörper
  • TP53I12 Antikörper

Bezeichner auf Proteinebene für PTGES

microsomal prostaglandin E synthase-1 , prostaglandin E synthase , MGST1-like 1 , glutathione S-transferase 1-like 1 , microsomal glutathione S-transferase 1-like 1 , microsomal prostaglandin E synthase 1 , p53-induced apoptosis protein 12 , p53-induced gene 12 protein , tumor protein p53 inducible protein 12

417193 Gallus gallus
654407 Sus scrofa
446534 Xenopus laevis
473071 Pan troglodytes
9536 Homo sapiens
64292 Mus musculus
59103 Rattus norvegicus
100733230 Cavia porcellus
282019 Bos taurus
480698 Canis lupus familiaris
100034143 Equus caballus
Ausgewählte Anbieter für anti-Prostaglandin E Synthase (PTGES) Antikörper
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