Peroxiredoxin 6 Proteine (PRDX6)

The protein encoded by PRDX6 is a member of the thiol-specific antioxidant protein family. Zusätzlich bieten wir Ihnen Peroxiredoxin 6 Antikörper (169) und Peroxiredoxin 6 Kits (21) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PRDX6 54683 P99029
PRDX6 9588 P30041
PRDX6 94167 O35244
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Showing 10 out of 30 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
525,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
419,05 €
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HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
523,81 €
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HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
328,90 €
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HOST_Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
285,71 €
Details
HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
365,71 €
Details

PRDX6 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

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Rat (Rattus) ,
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Am meisten referenzierte Peroxiredoxin 6 Proteine

  1. Human Peroxiredoxin 6 Protein expressed in Escherichia coli (E. coli) - ABIN2004161 : Kang, Baines, Rhee: Characterization of a mammalian peroxiredoxin that contains one conserved cysteine. in The Journal of biological chemistry 1998 (PubMed)
    Zeige alle 3 Referenzen für 2004161

  2. Human Peroxiredoxin 6 Protein expressed in Escherichia coli (E. coli) - ABIN667123 : Davison, Pennington, Hung, Peng, Rafiq, Ostareck-Lederer, Ostareck, Ardley, Banks, Robinson: Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function. in Proteomics 2009 (PubMed)
    Zeige alle 2 Referenzen für 667123

  3. Human Peroxiredoxin 6 Protein expressed in Wheat germ - ABIN1316165 : Jo, Yun, Park, Park, Lee, Cho, Yoo, Lee, Jeong, Kim, Jung, Hwang, Lee, Kim, Han, Hong: Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6. in PLoS ONE 2014 (PubMed)

Weitere Proteine zu Peroxiredoxin 6 (PRDX6) Interaktionspartnern

Xenopus laevis Peroxiredoxin 6 (PRDX6) Interaktionspartner

  1. Gene expressionof Prx6 increased during development, especially at stages 33-43 during formation of the lungs.

Mouse (Murine) Peroxiredoxin 6 (PRDX6) Interaktionspartner

  1. PRDX6 inhibited the carcinogenesis of hepatocellular carcinoma, and the calcium-independent phospholipase A2 (zeige LYPLA1 Proteine) activity of PRDX6 promoted cancer cell death induced by TNF-alpha (zeige TNF Proteine).

  2. Studies in knockout and knock-in mice showed that the phospholipase A2 (zeige YWHAZ Proteine) activity of peroxiredoxin 6 activates NOX2 (zeige CYBB Proteine) in cultured pulmonary endothelial cells and alveolar macrophages, clarifying the metabolism of lysophosphatidyl chold to lysophosphatidic acid.

  3. Prdx6 knockout males are more vulnerable to oxidative stress than WT males, resulting in impairment of sperm quality and ability to fertilize the oocyte, compatible with the subfertility phenotype observed in these knockout mice.

  4. Thr (zeige TRH Proteine) can substitute for Ser (zeige SIGLEC1 Proteine) for the enzymatic activities of Prdx6 but not for its targeting to LB. These results confirm an important role for LB Prdx6 in the degradation and remodeling of lung surfactant phosphatidylcholine (zeige SGMS2 Proteine).

  5. AP-3 (zeige AP3B1 Proteine)-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 (zeige SCARB2 Proteine) and PRDX6 in vitro and in vivo

  6. Prdx6 plays a critical role in the repair of peroxidized phospholipids in cell membranes and the recovery of lung cells from peroxidative stress; the peroxidase and PLA(2 (zeige PLA2G5 Proteine)) activity each contribute to the recovery process.

  7. The ventral signal observed from E12.5 on colocalized with motor neuron markers Isl1 (zeige ISL1 Proteine)/2 and FoxP1 (zeige FOXP1 Proteine) and The strong ventral signal colocalizing wtth Isl1 (zeige ISL1 Proteine)/2 was observed in all rostrocaudal segments of the spinal cord.

  8. PRDX6 has a role in controlling multiple sclerosis by suppressing inflammation and blood brain barrier disruption

  9. PRDX6 has an important role in dopaminergic neurodegeneration of Parkinson's disease.

  10. Our findings suggest that overexpression of peroxiredoxin 6 might promote development of rheumatoid arthritis through NF-kappaB (zeige NFKB1 Proteine) and AP-1 (zeige JUN Proteine) activity via the JNK (zeige MAPK8 Proteine) pathway.

Human Peroxiredoxin 6 (PRDX6) Interaktionspartner

  1. PRDX6 inhibited the carcinogenesis of hepatocellular carcinoma, and the calcium-independent phospholipase A2 (zeige PNPLA8 Proteine) activity of PRDX6 promoted cancer cell death induced by TNF-alpha (zeige TNF Proteine).

  2. the data demonstrate that Prdx6 interrupts the formation of TRAF6 (zeige TRAF6 Proteine)-ECSIT (zeige ECSIT Proteine) complex induced by TLR4 (zeige TLR4 Proteine) stimulation, leading to suppression of bactericidal activity because of inhibited mROS production in mitochondria and the inhibition of NF-kappaB (zeige NFKB1 Proteine) activation in the cytoplasm.

  3. Thus far only the crystal structure of Prx in the oxidized state has been reported. In this study, we present the crystal structures of human Prx6 in the reduced (SH) and the sulfinic acid (SO2H) forms.

  4. Peroxiredoxin 6 has a role in the repair of peroxidized cell membranes and cell signaling [review]

  5. PRDX6-anion exchanger 1 (zeige SLC4A1 Proteine) interaction contributes to the maintenance of anion exchanger 1 (zeige SLC4A1 Proteine) during cellular stress such as during metabolic acidosis.

  6. Prdx6 is a complete enzyme comprising both PLA2and LPCAT (zeige LPCAT3 Proteine) activities

  7. Our study provides new insight into the initial regulatory mechanisms of mitophagy and reveals the protective role of PRDX6 in the clearance of damaged mitochondria.

  8. Thr (zeige TRH Proteine) can substitute for Ser (zeige SIGLEC1 Proteine) for the enzymatic activities of Prdx6 but not for its targeting to LB. These results confirm an important role for LB Prdx6 in the degradation and remodeling of lung surfactant phosphatidylcholine (zeige SGMS2 Proteine).

  9. Prdx6 and its PLA2 (zeige YWHAZ Proteine) activity have a protective role in donors after brain death livers.

  10. PRDX6 may serve as a biomarker for traumatic brain injury and that autoimmune profiling is a viable strategy for the discovery of novel biomarkers

Pig (Porcine) Peroxiredoxin 6 (PRDX6) Interaktionspartner

  1. The expression of porcine Prdx6 gene is up-regulated by C/EBPbeta (zeige CEBPB Proteine) and CREB (zeige CREB1 Proteine).

  2. The SNP of PRDX6 gene was significantly associated with the intramuscular fat and water moisture.

Cow (Bovine) Peroxiredoxin 6 (PRDX6) Interaktionspartner

  1. study demonstrated involvement of cytosolic and calcium-independent phospholipase A (zeige HRASLS Proteine)(2) and the contribution of cyclooxygenase-2 (zeige PTGS2 Proteine) products in E. coli invasion of brain microvascular endothelial cells

  2. dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB (zeige CREB1 Proteine) phosphorylation mediated by iPLA2 (zeige PLA2G6 Proteine).

  3. PRDX6 upregulation in cumulus-oocyte complexes during in vitro maturation is mutually regulated by both cell types.

Peroxiredoxin 6 (PRDX6) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell\; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Genbezeichner und Symbole assoziert mit Peroxiredoxin 6 Proteine (PRDX6)

  • peroxiredoxin 6 (prdx6)
  • peroxiredoxin 5 (Prdx5)
  • peroxiredoxin 6 (PRDX6)
  • peroxiredoxin 6 (Prdx6)
  • 1-Cys Protein
  • 1-cysPrx Protein
  • 9430088D19Rik Protein
  • AA690119 Protein
  • aiPLA2 Protein
  • AOEB166 Protein
  • Aop2 Protein
  • Aop2-rs3 Protein
  • AOPP Protein
  • Brp-12 Protein
  • CC26 Protein
  • CP-3 Protein
  • GPx Protein
  • Ltw-4 Protein
  • Ltw4 Protein
  • Lvtw-4 Protein
  • mKIAA0106 Protein
  • NSGP Protein
  • NSGPx Protein
  • ORF06 Protein
  • p29 Protein
  • PHGPX Protein
  • Pmp20 Protein
  • Prdx5 Protein
  • Prdx6 Protein
  • Prdx6-rs3 Protein
  • PRX Protein
  • prx-6 Protein
  • prx6 Protein
  • PrxV Protein
  • zgc:73360 Protein

Bezeichner auf Proteinebene für Peroxiredoxin 6 Proteine (PRDX6)

peroxiredoxin 6 , PLP , antioxidant enzyme B166 , liver tissue 2D-page spot 2D-0014IV , peroxiredoxin V , peroxiredoxin-5, mitochondrial , peroxisomal antioxidant enzyme , peroxisomal membrane protein 20 , prx-V , thioredoxin peroxidase PMP20 , thioredoxin reductase , 1-Cys PRX , 1-Cys peroxiredoxin , 24 kDa protein , acidic calcium-independent phospholipase A2 , antioxidant protein 2 , liver 2D page spot 40 , non-selenium glutathione peroxidase , peroxiredoxin-6 , red blood cells page spot 12 , 1-Cys Prx , anti-oxidant protein 2, related sequence 3 , peroxiredoxin 5, related sequence 3 , peroxiredoxin 6, related sequence 3 , NSGPx , aiPLA2 , thiol-specific antioxidant protein , non-selenium glutathione phospholipid hydroperoxide peroxidase , PHGPx , anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) , calcium-independent phospholipase A2 , ciliary body glutathione peroxidase

GENE ID SPEZIES
394706 Xenopus (Silurana) tropicalis
398641 Xenopus laevis
496787 Xenopus (Silurana) tropicalis
100304983 Ictalurus punctatus
54683 Mus musculus
9588 Homo sapiens
11758 Mus musculus
94167 Rattus norvegicus
393778 Danio rerio
399434 Xenopus laevis
429062 Gallus gallus
399538 Sus scrofa
282438 Bos taurus
100173342 Pongo abelii
101842872 Mesocricetus auratus
Ausgewählte Anbieter für Peroxiredoxin 6 Proteine (PRDX6)
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