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The DNA-associated protein encoded by PRRX1 is a member of the paired family of homeobox proteins localized to the nucleus. Zusätzlich bieten wir Ihnen PRRX1 Proteine (8) und PRRX1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal PRRX1 Primary Antibody für IHC, IHC (p) - ABIN4348068
Hardin, Guo, Shan, Montemayor-Garcia, Asioli, Yu, Harrison, Chen, Lloyd: The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. in The American journal of pathology 2014
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Human Polyclonal PRRX1 Primary Antibody für ICC, IF - ABIN449553
Reichert, Takano, von Burstin, Kim, Lee, Ihida-Stansbury, Hahn, Heeg, Schneider, Rhim, Stanger, Rustgi: The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. in Genes & development 2013
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Human Polyclonal PRRX1 Primary Antibody für WB - ABIN1881690
Jiang, Stefanovic: Homeobox gene Prx1 is expressed in activated hepatic stellate cells and transactivates collagen alpha1(I) promoter. in Experimental biology and medicine (Maywood, N.J.) 2008
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Human Monoclonal PRRX1 Primary Antibody für ELISA, WB - ABIN1327183
Hirata, Sugimachi, Takahashi, Ueda, Sakimura, Uchi, Kurashige, Takano, Nanbara, Komatsu, Saito, Shinden, Iguchi, Eguchi, Atsumi, Sakamoto, Doi, Hirakawa, Honda, Mimori: Downregulation of PRRX1 Confers Cancer Stem Cell-Like Properties and Predicts Poor Prognosis in Hepatocellular Carcinoma. in Annals of surgical oncology 2014
Human Monoclonal PRRX1 Primary Antibody für IHC, WB - ABIN2674295
Guo, Fu, Wei, Lu, Feng, Zhang: PRRX1 promotes epithelial-mesenchymal transition through the Wnt/?-catenin pathway in gastric cancer. in Medical oncology (Northwood, London, England) 2014
LGR5 (zeige LGR5 Antikörper)-expressing fraction of CD54 (zeige ICAM1 Antikörper)+ cells represents gastric cancer CSCs, in which LGR5 (zeige LGR5 Antikörper) is closely associated with stemness and EMT (zeige ITK Antikörper) core genes
miR (zeige MLXIP Antikörper)-655 inhibits the acquisition of the epithelial-mesenchymal transition phenotype in triple-negative breast cancer by down-regulating Prrx1, thereby inhibiting cell migration and invasion during cancer progression.
Decreased Expression of PRRX1 was Associated with Hepatocellular Carcinoma.
the switch from Prrx1b to Prrx1a governs EMT (zeige ITK Antikörper) plasticity in both mouse models of PDAC and human PDAC
These findings demonstrate that PRRX1 promotes epithelial-mesenchymal transition in gastric cancer cells
Our results indicate that activation of Notch (zeige NOTCH1 Antikörper) signaling by PRRX1 is associated with the promotion of glioblastoma cell invasion.
We conclude that miR (zeige MLXIP Antikörper)-146b-5p has a role in cell proliferation and invasion, and that PRRX1 plays an important role in papillary thyroid carcinoma epithelial-mesenchymal transition and disease progression.
Overexpression of PRRX1 in stably overexpressed-miR (zeige MLXIP Antikörper)-124 cell lines could rescue the effects of radiosensitivity enhancement brought by miR (zeige MLXIP Antikörper)-124.
In the rare variant joint analysis, damaging variants within the PRRX1 region showed significant association with AF.
PRRX1 is an indicator of metastasis and poor prognosis in colorectal cancer cases.
Postnatal PRX1 (zeige PRDX1 Antikörper)-expressing stem cells of the calvaria are required for bone regeneration.
Data show that p38alpha (zeige MAPK14 Antikörper) mitogen-activated protein kinase (zeige MAPK1 Antikörper) (MAPK (zeige MAPK1 Antikörper)) in paired related homeobox 1 protein (Prx1 (zeige PRDX1 Antikörper)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG (zeige TNFRSF11B Antikörper)) production.
These data suggest the presence of a novel oxidative-stress-handling pathway where the anti-p53 (zeige TP53 Antikörper) molecule fortilin (zeige TPT1 Antikörper) augments the peroxidase PRX1 (zeige PRDX1 Antikörper) by protecting it against degradation and inactivation of the enzyme.
Induction of Prx1 (zeige PRDX1 Antikörper) by hypoxia regulates heme oxygenase-1 (zeige HMOX1 Antikörper) via NF-kappaB (zeige NFKB1 Antikörper) in oral cancer.
PRX-1 has a regulatory role in NF-kappaB (zeige NFKB1 Antikörper) nuclear translocation.
The data of this study suggested that Prx1 (zeige PRDX1 Antikörper) plays an important role as a key switch for neural cell lineage determination and the maintenance of the self-renewal of adult NSCs at several stages in the adult brain.
These observations suggest that increased Prrx1 expression may promote TGFbeta (zeige TGFB1 Antikörper) activity in adipose tissue and thereby contribute to aberrant adipocyte function during obesity.
The two isoforms, Prrx1a and Prrx1b, regulate migration and invasion, respectively, in pancreatic cancer cells
The results suggested that scarless skin-wound healing may require activation of the prx1 (zeige PRDX1 Antikörper) limb enhancer, and competence to activate the enhancer is probably a prerequisite for epimorphic regeneration, such as limb regeneration.
These results identify the homeobox protein (zeige HOXA1 Antikörper) Prx1 (zeige PRDX1 Antikörper) as an obligate mediator of TNF (zeige TNF Antikörper) inhibition of Osx (zeige SP7 Antikörper) and differentiation of osteoblast progenitors.
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.
paired mesoderm homeo box 1
, paired related homeobox 1
, paired mesoderm homeobox 1
, paired mesoderm homeobox protein 1
, similar to PEPP subfamily gene 2
, homeobox protein PHOX1
, paired mesoderm homeobox 1 isoform pmx-1b
, paired-related homeobox protein 1
, homeobox protein K-2
, homeobox protein mHox
, homeobox protein MHOX
, paired-related homeotic gene product