PHD Finger Protein 8 (PHF8) ELISA Kits

The protein encoded by PHF8 is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. Zusätzlich bieten wir Ihnen PHF8 Antikörper (34) und PHF8 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human PHF8 PHF8 23133 Q9UPP1
Anti-Ratte PHF8 PHF8 317425  
PHF8 320595 Q80TJ7
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus 0.118 ng/mL 0.312-20 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
896,09 €
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Weitere ELISA Kits für PHF8 Interaktionspartner

Human PHD Finger Protein 8 (PHF8) Interaktionspartner

  1. USP7 (zeige USP7 ELISA Kits) promotes breast carcinogenesis by stabilizing PHF8 and upregulating cyclin A2 (zeige CCNA2 ELISA Kits). and the interaction between USP7 (zeige USP7 ELISA Kits) and PHF8 is augmented during DNA damage.

  2. PHF8 reduces the H3K9me2 level at the E2F4 (zeige E2F4 ELISA Kits) transcriptional start site, demonstrating a direct function of PHF8 in endothelial E2F4 (zeige E2F4 ELISA Kits) gene regulation

  3. PHF2 (zeige PHF1 ELISA Kits) is likely to repress rDNA transcription by competing with PHF8 for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1 (zeige SUV39H1 ELISA Kits).

  4. PHF8 promotes lung cancer cell growth and survival by regulating miR (zeige MLXIP ELISA Kits)-21.

  5. knockdown of PHF8 led to a reduction in the number of migratory and invasive cells. Furthermore, downregulation of PHF8 attenuated the tumorigenicity of ESCC cells in vivo.

  6. PHF8 is regulated by APC (zeige APC ELISA Kits)(cdc20 (zeige CDC20 ELISA Kits)) and plays an important role in the G2/M transition.

  7. study identified the histone demethylase (zeige MBD2 ELISA Kits) PHF8 as a coactivator that is specifically recruited by RAR-alpha (zeige RARA ELISA Kits) fusions to activate expression of their downstream targets upon all-trans retinoic acid treatment in acute promyelocytic leukemia (zeige PML ELISA Kits)

  8. Results show that PHF8 controls the expression of genes involved in cell adhesion and cytoskeleton organization such as RhoA (zeige RHOA ELISA Kits), Rac1 and GSK3beta (zeige GSK3b ELISA Kits).

  9. a role of PHF8 in cell migration and invasion

  10. PHF8 is a histone demethylase and coactivator for RARalpha and that the F279S mutation identified in an XLMR patient results in loss of its demethylase activity.

Mouse (Murine) PHD Finger Protein 8 (PHF8) Interaktionspartner

  1. PHF8 overexpression reversed cardiac dysfunction, hypertrophy and fibrosis upon pressure overload in PHF8 transgenic mice.

  2. The gene knockdown of PHF8 in mouse embryonic carcinoma P19 cells impairs RA-induced neuronal differentiation.

  3. an important function of PHF8 is in midline formation and in the development of cognitive abilities, and may have a role in X linked mental retardation associated with cleft lip/palate

Zebrafish PHD Finger Protein 8 (PHF8) Interaktionspartner

  1. PHF8 regulates zebrafish neuronal cell survival and jaw development in part by directly regulating the expression of the homeodomain transcription factor MSX1/MSXB, which functions downstream of multiple signalling and developmental pathways

PHF8 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PHD Finger Protein 8 (PHF8) ELISA Kits

  • PHD finger protein 8 (PHF8) Antikörper
  • PHD finger protein 8 (Phf8) Antikörper
  • PHD finger protein 8 (phf8) Antikörper
  • RIKEN cDNA 4921501E09 gene (4921501E09Rik) Antikörper
  • 9830141C09Rik Antikörper
  • JHDM1F Antikörper
  • mKIAA1111 Antikörper
  • MRXSSD Antikörper
  • PHF8 Antikörper
  • RGD1561065 Antikörper
  • ZNF422 Antikörper
  • zPHF8 Antikörper

Bezeichner auf Proteinebene für PHD Finger Protein 8 (PHF8) ELISA Kits

histone lysine demethylase PHF8 , jumonji C domain-containing histone demethylase 1F , KIAA1111-like protein , PHD finger protein 8-like

GENE ID SPEZIES
23133 Homo sapiens
491897 Canis lupus familiaris
100520413 Sus scrofa
513959 Bos taurus
317425 Rattus norvegicus
320595 Mus musculus
566534 Danio rerio
74042 Mus musculus
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