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Modulates arousal and anxiety. Zusätzlich bieten wir Ihnen NPS Kits (28) und NPS Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Findings demonstrate that neuropeptide S, via selective activation of the neurons bearing neuropeptide S receptor (zeige NPSR1 Antikörper) in the subiculum complex, ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 in mice.
these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN.
Study demonstrated that NPS produces anti-aggressive effects in mice through the selective activation of NPSR (zeige NPSR1 Antikörper) and that the endogenous NPS/NPSR (zeige NPSR1 Antikörper) system can exert a role in the control of aggressiveness levels under the present experimental conditions
These data provide evidence for a direct interaction between the corticotropin-releasing factor (zeige CRH Antikörper) and the NPS system and thereby extend previous observations of NPS-modulated stress responsiveness towards a mechanistic level.
Neuropeptide S knock-out mice display deficits in inhibitory avoidance memory indicating involvement in central noradrenergic systems.
Results describe the neuroanatomical, molecular, and functional aspects of neuropeptide S-producing neurons in the mouse brain.
These data demonstrate that the distribution pattern of the central neuropeptide S system is only partially conserved between mice and rats.
results demonstrate that neuropeptide S and NPSR1 (zeige NPSR1 Antikörper) regulate respiratory function through a central nervous system-mediated pathway
Data suggest that lithium evokes antagonistic effects on the mediation of hyperlocomotion and protection against lipid peroxidation induced by neuropeptide S.
analysis of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus
A SNP within the neuropeptide s gene is associated with decreased bioactivity.
NPS is able to stimulate human monocyte chemotaxis and that this effect is entirely due to selective NPSR (zeige NPSR1 Antikörper) activation.
The available information regarding NPS and its receptor and the biological actions modulated by the NPS-NPSR (zeige NPSR1 Antikörper) system, is summarized.
NPS-NPSR1 (zeige NPSR1 Antikörper) signaling is likely involved in anxiety
NPS has a novel role in the stimulation of the hypothalamo-pituitary-adrenal axis
the C-terminal region of neuropeptide S maintains importance for in vivo activity
the key residues of NPS involved in NPSR (zeige NPSR1 Antikörper) activation and suggest a molecular basis for the functional effects of the N107I mutation and for its putative pathophysiological link with asthma
Because remodeling of airway epithelium is a feature of chronic asthma, the up-regulation of MMP10 (zeige MMP10 Antikörper) and TIMP3 (zeige TIMP3 Antikörper) by NPS-NPSR1 (zeige NPSR1 Antikörper) signaling may be of relevance in the pathogenesis of asthma.
NPS acts as a novel modulator of arousal and anxiety-related behaviours by promoting a unique pattern of effects: stimulation associated with anxiolysis.
Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity).
, neuropeptide S