Neuroglobin Proteine (NGB)

NGB encodes an oxygen-binding protein that is distantly related to members of the globin gene family. Zusätzlich bieten wir Ihnen Neuroglobin Antikörper (85) und Neuroglobin Kits (52) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NGB 69237 Q99ME9
NGB 58157 Q9NPG2
NGB 85382 Q99JA8
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.222,70 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.222,70 €
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Hefe Macaca mulatta His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.222,70 €
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Hefe Pan troglodytes His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.222,70 €
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.222,70 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.222,70 €
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NGB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)
,
Human , ,
, , , ,
Rat (Rattus)

Am meisten referenzierte Neuroglobin Proteine

  1. Human Neuroglobin Protein expressed in Wheat germ - ABIN1312525 : Powers: p53-mediated apoptosis, neuroglobin overexpression, and globin deposits in a patient with hereditary ferritinopathy. in Journal of neuropathology and experimental neurology 2006 (PubMed)

Weitere Proteine zu Neuroglobin (NGB) Interaktionspartnern

Mouse (Murine) Neuroglobin (NGB) Interaktionspartner

  1. Findings provide evidence for the loss of globin-linked neuroprotection to be linked to Alzheimer's disease angiopathogenesis, while raising the possibility of REST/ NRSF being an upstream regulator.

  2. Ngb expression is limited to the subpopulation of typ (zeige UBXN11 Proteine)e I spiral ganglion cells, those which innervate inner hair cell (zeige UBXN11 Proteine)s, while the subpopulation of type II spiral ganglion cells which innervate the outer hair cells do not express Ngb. The cochlear nuclei and superior olivary complex (SOC) also express considerable amounts of Ngb.

  3. Ngb functions as a metabolic regulator and enhances cellular anabolism through the inhibition of AMPK (zeige PRKAA1 Proteine) signaling.

  4. Data show that the neuroglobin (Ngb) protein was downregulated in the retinal ganglion cells after optic nerve injury.

  5. Overexpression of neuroglobin reduced sensorimotor deficits following TBI. An endogenous increase in neuroglobin expression occurs during the subacute period. Increasing neuroglobin expression during the acute period after TBI may improve recovery.

  6. reflect lesser perturbations produced by acute inhalation of combustion smoke in the Ngb overexpressing mouse, suggesting that Ngb mitigates mitochondrial dysfunction and neurotoxicity and raises the threshold of smoke inhalation-induced brain injury

  7. A critical role for neuroglobin is demonstrated via its differential interaction with phosphatase and tensin homolog (PTEN) and Akt during neurite induction.

  8. Neuroglobin overexpression resulted in a significant reduction in infarct volume 24 hours after brain ischemia.

  9. Ngb overexpression can inhibit oxygen-glucose deprivation-induced mitochondria permeability transition opening in primary cultured mouse cortical

  10. CREB (zeige CREB1 Proteine) may also mediate transcriptional regulation of neuroglobin gene.

Human Neuroglobin (NGB) Interaktionspartner

  1. these results highlight the involvement of ERa activation and of E2/ERa-dependent NGB (zeige GTPBP4 Proteine) upregulation in the insensitivity of MCF-7 to paclitaxel. These novel findings could have important implications in the development of targeted therapeutics for overcoming paclitaxel insensitivity in ERa-positive human breast cancer

  2. Knockdown of GATA-2 (zeige GATA2 Proteine) caused NGB (zeige GTPBP4 Proteine) expression to drop dramatically, indicating GATA-2 (zeige GATA2 Proteine) as an essential transcription factor for the activation of NGB (zeige GTPBP4 Proteine) expression via binding to a novel distal regulatory element of NGB (zeige GTPBP4 Proteine).

  3. analysis of how the interaction of hydrogen sulfide (zeige SQRDL Proteine) with human neuroglobin is muted (zeige MUTED Proteine) by a distal ligand

  4. NO oxidation kinetics at physiological NO concentrations. The use of a polarized electrode to efficiently interconvert the ferric (Fe(3+)) and ferrous (Fe(2+)) forms of an immobilized NGB (zeige GTPBP4 Proteine) showed that the disulfide bridge both defines the kinetics of NO dioxygenase activity and regulates appearance of the free ferrous deoxy-NGB (zeige GTPBP4 Proteine), which is the redox active form of the protein in contrast to oxy (zeige GCG Proteine)-NGB (zeige GTPBP4 Proteine).

  5. Taken together, this work support the first evidence that Ngb (zeige GTPBP4 Proteine) can be potentially used as a promising biomarker and target for novel treatment of human glioma

  6. The cochlear nuclei and superior olivary complex (SOC (zeige UBXN11 Proteine)) also express considerable amounts of Ngb (zeige GTPBP4 Proteine). Within the human SOC (zeige UBXN11 Proteine), many medial superior olive neurons, and scattered neurons in the LSO, were Ngb (zeige GTPBP4 Proteine)-immunoreactive

  7. Study characterized the presence of Ngb (zeige GTPBP4 Proteine) in the human cochlea

  8. Data show that the mean peak serum neuroglobin and Nogo-A concentrations were both significantly higher in patients with an unfavorable outcome at 6 months after traumatic brain injury (TBI).

  9. Neuroglobin player role in estrogen receptor alpha (zeige ESR1 Proteine)-positive cancer cell viability.

  10. a mechanism for redox control of human Ngb (zeige GTPBP4 Proteine) (hNgb) activity

Pig (Porcine) Neuroglobin (NGB) Interaktionspartner

  1. Constitutive expression levels of neuroglobin in neonatal brain cells may explain mild neuronal injury after 60 min. of deep hypothermic circulatory arrest.

Rabbit Neuroglobin (NGB) Interaktionspartner

  1. Ngb overexpression may have potential therapeutic benefits for both reducing secondary damages and improving the outcomes after traumatic spinal cord injury

Zebrafish Neuroglobin (NGB) Interaktionspartner

  1. The zebrafish Neuroglobin can catalyze the reduction of nitrite to nitric oxide with a broad range of reaction rate constants.

  2. Data show that the neuroglobin (Ngb) protein was upregulated in the amacrine cells after optic nerve injury.

  3. Chimeric Myoglobin (zeige MB Proteine) has a cell-membrane-penetrating activity similar to zebrafish Ngb.

  4. Neuroglobin appears to be associated with mitochondria-rich cell types and thus oxygen consumption rates, suggesting a myoglobin (zeige MB Proteine)-like function of this protein in facilitated oxygen diffusion

  5. both zebrafish and chimeric ZHHH Ngb can penetrate cell membranes in the absence of Chariot

Neuroglobin (NGB) Protein Überblick

Protein Überblick

This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.

Genbezeichner und Symbole assoziert mit Neuroglobin Proteine (NGB)

  • neuroglobin (ngb)
  • neuroglobin (NGB)
  • GTP binding protein 4 (Gtpbp4)
  • neuroglobin (Ngb)
  • 2610028C09Rik Protein
  • Crfg Protein
  • Gtpbp3 Protein
  • ngb Protein
  • Nog1 Protein

Bezeichner auf Proteinebene für Neuroglobin Proteine (NGB)

neuroglobin , GTP binding protein 3 , GTP-binding protein NGB , Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB) , chronic renal failure gene protein , chronic renal failure protein , nucleolar GTP-binding protein 1

GENE ID SPEZIES
594898 Xenopus (Silurana) tropicalis
641332 Monodelphis domestica
734191 Xenopus laevis
69237 Mus musculus
58157 Homo sapiens
64242 Mus musculus
85382 Rattus norvegicus
414438 Sus scrofa
414920 Bos taurus
100008868 Oryctolagus cuniculus
100379566 Cavia porcellus
442944 Canis lupus familiaris
428896 Gallus gallus
443260 Ovis aries
641331 Macaca mulatta
100000711 Danio rerio
467518 Pan troglodytes
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