anti-Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2) Antikörper

NPR2 encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Zusätzlich bieten wir Ihnen NPR2 Proteine (37) und NPR2 Kits (20) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NPR2 230103 Q6VVW5
NPR2 4882 P20594
NPR2 116564 P16067
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Top anti-NPR2 Antikörper auf

Showing 10 out of 77 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-NPRB/Natriuretic Peptide Receptor B Polyclonal Antibody, Unconjugated (ABIN679778) at 1:200 followed by conjugation to the secondary antibody 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Human Kaninchen Unkonjugiert IHC (p) 1 mL Anmelden zum Anzeigen 25 bis 36 Tage
488,19 €
Maus Kaninchen Unkonjugiert WB Mouse Npr2 Antibody (Center) (ABIN658174) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the Npr2 antibody detected the Npr2 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Human Kaninchen Unkonjugiert IHC (fro), WB 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
484,00 €
Human Maus Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
583,00 €
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: Natriuretic Peptide Receptor B Antibody [NBP1-82538] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY416577) Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor B Antibody [NBP1-82538] - Staining of human colon shows moderate cytoplasmic and nuclear positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Human Kaninchen Unkonjugiert WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
484,00 €
Human Maus Unkonjugiert IHC (p), ELISA, WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
426,22 €
Fledermaus Kaninchen Unkonjugiert ELISA, WB   20 μL Anmelden zum Anzeigen 11 bis 14 Tage
740,31 €

NPR2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,

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Am meisten referenzierte anti-NPR2 Antikörper

  1. Human Polyclonal NPR2 Primary Antibody für IF (p), IHC (p) - ABIN679778 : Li, Tang, Cai, Qiu, Lin, Zhu, Owusu, Guo: CNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan. in World journal of gastroenterology : WJG 2015 (PubMed)

Weitere Antikörper gegen NPR2 Interaktionspartner

Mouse (Murine) Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2) Interaktionspartner

  1. E2-ERs system was functional in maintaining oocyte meiotic arrest by regulating the expression of natriuretic peptide C (zeige NPPC Antikörper) and natriuretic peptide receptor 2 (NPPC (zeige NPPC Antikörper)/NPR2 (zeige NPRL2 Antikörper))

  2. NPR2 (zeige NPRL2 Antikörper) is involved in FSH (zeige BRD2 Antikörper)-mediated oocyte meiotic resumption, and this process is associated with the EGFR (zeige EGFR Antikörper) and MAPK3 (zeige MAPK3 Antikörper)/1 signaling pathways.

  3. NPR2 (zeige NPRL2 Antikörper) dephosphorylation in the mural granulosa cells is essential for the normal progression of meiosis in response to LH and EGF receptor (zeige EGFR Antikörper) activation.

  4. Npr2 (zeige NPRL2 Antikörper) is necessary for the precise spatial organization typical of central auditory circuits, but signals are still transmitted with normal timing, and that mutant mice can hear even with these deficits.

  5. Npr2 (zeige NPRL2 Antikörper) is expressed in hard calluses of wild-type mice, suggesting a possible role of CNP (zeige CNP Antikörper) signaling in fracture repair, especially in bone remodeling stage.

  6. Data, including data from mutant mice strain Npr2 (zeige NPRL2 Antikörper)(slw/slw), suggest that Npr2 (zeige NPRL2 Antikörper) is critical for fertility but role of Npr2 (zeige NPRL2 Antikörper) may be more involved in penile function rather than involved in spermatogenesis.

  7. These findings demonstrate that pNPPB may be used as a probe to identify the essential amino acid sequences for activation of NPR2 (zeige NPRL2 Antikörper).

  8. GATA2 (zeige GATA2 Antikörper) and Lmo2 (zeige LMO2 Antikörper) cooperatively regulate VEGF (zeige VEGFA Antikörper)-induced angiogenesis and lymphangiogenesis via NRP2 (zeige NRP2 Antikörper).

  9. Data suggest that epidermal growth factor (Egf)/Egf (zeige EGF Antikörper) receptor (zeige EGFR Antikörper) signaling in cumulus cells (CC) down-regulates Npr2 (zeige NPRL2 Antikörper), decreases cGMP, elevates calcium, and induces meiotic resumption/oogenesis in cultured CC-oocyte complexes (in induced meiotic arrest).

  10. CNP (zeige CNP Antikörper)/NPR2 (zeige NPRL2 Antikörper) signaling is essential for oocyte meiotic arrest in early antral follicles and activated LH/amphiregulin (zeige AREG Antikörper)/EGFR (zeige EGFR Antikörper) signaling pathway suppresses this signal by downregulating Nppc (zeige NPPC Antikörper) expression.

Human Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2) Interaktionspartner

  1. Atenolol treatment normalized the altered expression of Npr1 (zeige NPR1 Antikörper) and Npr2 (zeige NPRL2 Antikörper) genes.

  2. Data suggest mutations in NPR2 (zeige NPRL2 Antikörper) in patients with skeletal overgrowth alter conformation: A488P/R655C missense mutations yield conformation mimicking allosterically activated NPR2 (zeige NPRL2 Antikörper); A488P mutation sets phosphorylation as requirement for CNP (zeige CNP Antikörper)-dependent activation; R655C mutation abrogates need for phosphorylation; ATP analog inhibits mutants. (NPR2 (zeige NPRL2 Antikörper) = atrial natriuretic factor (zeige NPPA Antikörper) receptor B; CNP (zeige CNP Antikörper) = C-type natriuretic peptide (zeige NPPC Antikörper))

  3. Heterozygous mutation in NPR2 (zeige NPRL2 Antikörper) gene is associated with short stature.

  4. Mutations in three genes (GDF5 (zeige GDF5 Antikörper), NPR2 (zeige NPRL2 Antikörper), BMPR1B (zeige BMPR1B Antikörper)) have been reported to cause different forms of acromesomelic dysplasia

  5. IL1R2 (zeige IL1R2 Antikörper) hypomethylation and androgen receptor (zeige AR Antikörper) hypermethylation may constitute an important determinant of disease severity, whereas NPR2 (zeige NPRL2 Antikörper) hypomethylation and SP140 (zeige SP140 Antikörper) hypermethylation may provide a biomarker for vulnerability to excessive daytime sleepiness in Obstructive Sleep Apnea

  6. Loss-of-function mutations of the NPR2 (zeige NPRL2 Antikörper) gene is associated with acromesomelic dysplasia, type maroteaux.

  7. NPR2 (zeige NPRL2 Antikörper) mutations account for approximately 3% of patients with disproportionate short stature and/or clinical or radiographic indicators of SHOX (zeige SHOX Antikörper) deficiency and in whom no SHOX (zeige SHOX Antikörper) defect has been identified.

  8. 3 consanguineous families segregating Acromesomelic dysplasia Maroteaux type in an autosomal recessive manner studied. Linkage in the families was established to the NPR2 (zeige NPRL2 Antikörper) gene on chromosome 9p12-21. Sequence analysis revealed 2 novel missense variants (p.Arg601Ser; p.Arg749Trp) in 2 families and a previously reported splice site variant (c.2986+2T>G) in the third family.

  9. Cardiac fibrosis and the endogenous natriuretic peptide system were evaluated in end-stage heart failure to assess the anti-fibrotic actions of the dual GC-A (zeige NPR1 Antikörper)/-B activator.

  10. Gene expression of C-type natriuretic peptide (zeige NPPC Antikörper) and of its specific receptor NPR-B in human leukocytes of healthy and heart failure subjects

Cow (Bovine) Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2) Interaktionspartner

  1. These data support the existence of a novel transducing cascade, involving Galpha (zeige SUCLG1 Antikörper)(q16)beta gamma coupling M(3)AChR to NPR (zeige NPTXR Antikörper)-GC.

  2. NPR-B is a highly regulated nano-machinery with domains acting at cross-talk points with other signal transducing cascades initiated by G protein-coupled receptors

  3. ATP is not required for the initial activation of natriuretic peptide receptor A (zeige NPR1 Antikörper) and B, but does increase activity over time by reducing the apparent K(m) for GTP (zeige AK3 Antikörper).

NPR2 Antigen-Profil

Protein Überblick

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Genbezeichner und Symbole assoziert mit NPR2

  • natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2) Antikörper
  • natriuretic peptide receptor 2 (Npr2) Antikörper
  • natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (Npr2) Antikörper
  • AMDM Antikörper
  • ANPb Antikörper
  • ANPRB Antikörper
  • cn Antikörper
  • GC-B Antikörper
  • GC-B2 Antikörper
  • GC-B3 Antikörper
  • GUC2B Antikörper
  • GUCY2B Antikörper
  • mNPR-B Antikörper
  • NPR-B Antikörper
  • NPR2 Antikörper
  • NPRB Antikörper
  • NPRBi Antikörper
  • pwe Antikörper

Bezeichner auf Proteinebene für NPR2

natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) , natriuretic peptide receptor 2 , ANP-B , ANPR-B , NPR-B , Nppb receptor , atrial natriuretic peptide receptor 2 , atrial natriuretic peptide receptor type B , guanylate cyclase B , guanylyl cyclase-B , natriuretic peptide receptor B type , GC-B , atrial natriuretic peptide B-type receptor , ANPRB , atrial natriuretic peptide receptor B , natriuretic peptide receptor-B , atrionatriuretic peptide receptor B

692193 Sus scrofa
230103 Mus musculus
4882 Homo sapiens
116564 Rattus norvegicus
281357 Bos taurus
Ausgewählte Anbieter für anti-NPR2 (NPR2) Antikörper
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