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Midline 1 Proteine (MID1)

The protein encoded by MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. Zusätzlich bieten wir Ihnen MID1 Antikörper (58) und MID1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MID1 17318 O70583
MID1 4281 O15344
MID1 54252 P82458
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Top MID1 Proteine auf

Showing 7 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Hefe Maus His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.095,24 €
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.748,73 €
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
HOST_Escherichia coli (E. coli) Maus T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
685,71 €

MID1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,
Human , ,
, ,
Rat (Rattus)

Weitere Proteine zu Midline 1 (MID1) Interaktionspartnern

Mouse (Murine) Midline 1 (MID1) Interaktionspartner

  1. we show that MID1 controls exocytosis of lytic granules and cytotoxicity in murine cytotoxic lymphocytes

  2. X-linked microtubule-associated protein (zeige SPAG5 Proteine), Mid1, regulates axon development.

  3. MID1 inhibition also limited rhinovirus-induced exacerbation of allergic airway disease

  4. Thus, lack of Mid1 causes a misspecification of the midbrain/cerebellar boundary that results in an abnormal development of the most anterior cerebellar lobes.

  5. Analysis of Mid1, Hccs (zeige HCCS Proteine), Arhgap6 (zeige ARHGAP6 Proteine), and Msl3l1 (zeige MSL3 Proteine) in X-linked polydactyly (Xpl) and Patchy-fur (Paf (zeige KIAA0101 Proteine)) mutant mice

Human Midline 1 (MID1) Interaktionspartner

  1. the coiled-coil and COS domain (CC-COS) bind to microtubules, demonstrating for the first time that MID1 can directly associate with the microtubules

  2. Osx is upregulated in patients with Ossification of the posterior longitudinal ligament.

  3. A130T/V mutations within the MID1 zinc-binding Bbox1 (zeige BBOX1 Proteine) domain affects protein folding.

  4. MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 (zeige BBOX1 Proteine) domain disrupt polyubiquitination of alpha4 but not of PP2Ac (zeige PPP2CA Proteine) in X-linked Opitz syndrome.

  5. TRAIL regulates MID1 and TSLP (zeige TSLP Proteine), inflammation, fibrosis, smooth muscle hypertrophy, and expression of inflammatory effector chemokines and cytokines in experimental eosinophilic esophagitis.

  6. These studies provide insight into the mechanism by which mutations observed in X-linked Opitz G syndrome affect the structure and function of the MID1 Bbox1 (zeige BBOX1 Proteine) domain

  7. A familial c.1102C>T (p.R368X) mutation in the MID1 gene, is reported.

  8. Results revealed S422 as a novel phosphorylation site of Osx and GSK-3b played an important role in regulating the protein stability and transactivational activity of Osx.

  9. Fu ubiquitination and cleavage is one of the key elements connecting the MID1-PP2A (zeige PPP2R4 Proteine) protein complex with GLI3 (zeige GLI3 Proteine) activity control

  10. Promotion of AR, in addition to enhancement of the Akt (zeige AKT1 Proteine)-, NFkappaB (zeige NFKB1 Proteine)-, and Hh-pathways by sustained MID1-upregulation during androgen deprivation therapy provides a powerful proliferative scenario for PCa (zeige FLVCR1 Proteine) progression into castration resistance

MID1 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing\; however, the full-length nature of some of the variants has not been determined.

Genbezeichner und Symbole assoziert mit Midline 1 Proteine (MID1)

  • midline 1 (Mid1)
  • midline 1 (Opitz/BBB syndrome) (mid1)
  • midline 1 (Opitz/BBB syndrome) (MID1)
  • midline 1 (Opitz/BBB syndrome) (Mid1)
  • 61B3-R Protein
  • BBBG1 Protein
  • DXHXS1141 Protein
  • FXY Protein
  • GBBB1 Protein
  • MIDIN Protein
  • Midline1 Protein
  • OGS1 Protein
  • OS Protein
  • OSX Protein
  • RNF59 Protein
  • TRIM18 Protein
  • XPRF Protein
  • ZNFXY Protein

Bezeichner auf Proteinebene für Midline 1 Proteine (MID1)

midin , midline-1 , tripartite motif-containing protein 18 , RING finger protein 59 , midline 1 RING finger protein , putative transcription factor XPRF , tripartite motif protein TRIM18 , zinc finger on X and Y, mouse, homolog of , Finger on X and Y (in rat only on X)

17318 Mus musculus
100330952 Danio rerio
100463496 Xenopus laevis
373920 Gallus gallus
4281 Homo sapiens
491737 Canis lupus familiaris
534604 Bos taurus
54252 Rattus norvegicus
100524415 Sus scrofa
Ausgewählte Anbieter für MID1 Proteine (MID1)
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