Lectin, Mannose-Binding, 1 (LMAN1) ELISA Kits

The protein encoded by LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. Zusätzlich bieten wir Ihnen LMAN1 Antikörper (39) und LMAN1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
LMAN1 3998 P49257
LMAN1 70361 Q9D0F3
LMAN1 116666 Q62902
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Top LMAN1 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Menge Anbieter Lieferzeit Preis Details
Human 31 pg/mL 0.312-20 ng/mL 96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
716,57 €
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Human 46.9 pg/mL 78-5000 pg/mL 96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
452,57 €
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Maus
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
860,54 €
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Ratte
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
860,54 €
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Weitere ELISA Kits für LMAN1 Interaktionspartner

Human Lectin, Mannose-Binding, 1 (LMAN1) Interaktionspartner

  1. Genetic variants in the exon1 of MBL gene per se are not risk factors for Systemic lupus erythematosus (SLE) in South Indian Tamils. However, the association of codon 54 (rs1800450) with medium vessel vasculitis suggests that it may be a genetic modifier of clinical phenotype in SLE.

  2. Mannan-binding lectin (zeige MBL2 ELISA Kits) reduces CpG DNA-induced inflammatory cytokine production in monocytes.

  3. MMP-9 (zeige MMP9 ELISA Kits) secretion was reduced in the LMAN1 knockout cell line compared to control cells confirming the functional role of LMAN1.

  4. Authors identified a class of pathogen-derived ERGIC-53 ligands, a lectin-independent basis for their association with ERGIC-53, and a role for ERGIC-53 in the propagation of several highly pathogenic RNA virus families.

  5. Studies indicate that the LMAN1-CRD (zeige CRX ELISA Kits) contains distinct, separable binding sites for both its partner protein MCFD2 (zeige MCFD2 ELISA Kits) and the cargo proteins FV/FVIII (zeige F8 ELISA Kits).

  6. Data indicate that together with its soluble coreceptor MCFD2 (zeige MCFD2 ELISA Kits), LMAN1 transports coagulation factors V (FV) and VIII (zeige COX8A ELISA Kits) (FVIII (zeige F8 ELISA Kits)).

  7. Mutations in LMAN1 lead to F5F8D (combined deficiency of factor V And factor VIII) due to alterations in LMAN1-MCFD2 (zeige MCFD2 ELISA Kits) complex of coat protein (zeige GOLPH3 ELISA Kits) (COP (zeige CARD16 ELISA Kits))II complex trafficking machinery; 70% of F5F8D patients have mutations in LMAN1. [REVIEW]

  8. UBXD1 (zeige UBXN6 ELISA Kits) modulates the trafficking of ERGIC-53-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53.

  9. Two new mutations at ERGIC-53 gene in a Turkish family.

  10. Data present the crystal structure of the LMAN1/MCFD2 (zeige MCFD2 ELISA Kits) complex and relate it to patient mutations. Circular dichroism data show that the majority of the substitution mutations give rise to a disordered or severely destabilized MCFD2 (zeige MCFD2 ELISA Kits) protein.

Mouse (Murine) Lectin, Mannose-Binding, 1 (LMAN1) Interaktionspartner

  1. LMAN1 may play a role in photoreceptor gene transport and homeostasis.

  2. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of alpha1-antitrypsin.

  3. surfactant proteins A and D and mannose-binding lectin (zeige MBL2 ELISA Kits) play roles in inflammation caused by DNA in lungs and other tissues

  4. ERGIC-53 gene transcription is regulated in response to endoplasmic reticulum stress

LMAN1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Genbezeichner und Symbole assoziert mit LMAN1

  • lectin, mannose-binding, 1 (LMAN1) Antikörper
  • complexin 3 (cplx3) Antikörper
  • lectin, mannose-binding, 1 (lman1) Antikörper
  • lectin, mannose-binding, 1 (Lman1) Antikörper
  • 2610020P13Rik Antikörper
  • AI326273 Antikörper
  • AU043785 Antikörper
  • C730041J05 Antikörper
  • cpx-iii Antikörper
  • cpxiii Antikörper
  • ERGIC-53 Antikörper
  • ERGIC53 Antikörper
  • F5F8D Antikörper
  • FMFD1 Antikörper
  • gp58 Antikörper
  • lman1 Antikörper
  • lman1-a Antikörper
  • MCFD1 Antikörper
  • MR60 Antikörper
  • P58 Antikörper
  • wu:fc54c09 Antikörper
  • wu:fi36e01 Antikörper
  • Xp58 Antikörper

Bezeichner auf Proteinebene für LMAN1

lectin, mannose-binding, 1 , lectin mannose-binding 1 , ER-Golgi intermediate compartment 53 kDa protein , protein ERGIC-53 , protein ERGIC-53-like , fc54c09 , fi36e01 , endoplasmic reticulum-golgi intermediate compartment protein 53 , intracellular mannose specific lectin , intracellular mannose-specific lectin MR60 , ERGIC-53 protein , intracellular mannose specific lectin MR60

GENE ID SPEZIES
431779 Canis lupus familiaris
455448 Pan troglodytes
496634 Xenopus (Silurana) tropicalis
697449 Macaca mulatta
100021881 Monodelphis domestica
100354112 Oryctolagus cuniculus
100404326 Callithrix jacchus
100475249 Ailuropoda melanoleuca
100562643 Anolis carolinensis
100592766 Nomascus leucogenys
559775 Danio rerio
394295 Xenopus laevis
426849 Gallus gallus
3998 Homo sapiens
476186 Canis lupus familiaris
511649 Bos taurus
70361 Mus musculus
116666 Rattus norvegicus
Ausgewählte Anbieter für LMAN1 (LMAN1) ELISA Kits
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