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LAMC2 Proteine

(Laminin, gamma 2 (LAMC2))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 2. The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain\; however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney. The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction. Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described. The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known. Transcript variants utilizing alternative polyA_signal have also been noted in literature. [provided by RefSeq, Aug 2011].
LAMC2 Protein (AA 1084-1193) (His tag) LAMC2 Protein (AA 1084-1193) (His tag) LAMC2 Protein (AA 1084-1193) (His tag) (ABIN7123715)

LAMC2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

LAMC2 Protein (AA 1084-1193) (GST tag) LAMC2 Protein (AA 1084-1193) (GST tag) LAMC2 Protein (AA 1084-1193) (GST tag) (ABIN1309132)

LAMC2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA

LAMC2 Protein (AA 28-196) (His tag) (ABIN7395860)

LAMC2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

LAMC2 Proteine nach Origin

Hier sind LAMC2 Proteine für eine Vielzahl von Species wie anti-Human LAMC2, anti-Mouse LAMC2, anti-Rat LAMC2 zu finden. Die unten aufgeführten Species gehören zu den verfügbaren Arten. Klicken Sie auf einen Link, um zu den entsprechenden Produkten zu gelangen.

LAMC2 Proteine nach Source

Hier finden Sie LAMC2 Proteine Proteine, die nach mehreren wichtigen Quellen organisiert sind. Durch Anklicken eines Links können Sie auf die Produkte zugreifen. Für zusätzliche Quellen nutzen Sie bitte unsere Suchfunktion.

LAMC2 Proteine nach Protein-Typ

Hier können Sie LAMC2 Proteine Proteine finden, die nach verfügbaren Proteintypen kategorisiert sind. Zusätzliche Proteintypen können mit unserer Suchfunktion gefunden werden.

LAMC2 Proteine nach Anwendung

Hier sind LAMC2 Proteine zu finden, welche für eine bestimmte Anwendung wie WB, SDS, Imm, PC validiert wurde. Einige der verfügbaren Anwendungen sind unten aufgeführt. Klicken Sie auf einen Link, um zu den entsprechenden Produkten zu gelangen.

Häufig verwendete LAMC2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123715
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1309132
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7395860
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7414768
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7414864
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7415071
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7404002
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN6964244
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3010420
Menge 100 μg
Datenblatt Datenblatt

Aliase für LAMC2 Proteine

laminin subunit gamma 2 (LAMC2) Proteine
laminin, gamma 2 (Lamc2) Proteine
laminin subunit gamma 2 (Lamc2) Proteine
AA589349 Proteine
B2T Proteine
BM600 Proteine
CSF Proteine
EBR2 Proteine
EBR2A Proteine
LAMB2T Proteine
LAMC2 Proteine
LAMNB2 Proteine
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