anti-Laminin, alpha 2 (LAMA2) Antikörper

Laminin, an extracellular protein, is a major component of the basement membrane. Zusätzlich bieten wir Ihnen Laminin Kits (3) und Laminin Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LAMA2 3908 P24043
LAMA2 16773  
LAMA2 309368  
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Top anti-Laminin Antikörper auf

Showing 10 out of 55 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to LAMA2 on formalin-fixed paraffin-embedded human pancreas (antibody concentration 1 µg/mL). 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using LAMA2 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of NIH-3T3 cells, using LAMA2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Human Kaninchen Unkonjugiert WB Anti-Laminin 2 alpha antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: A549 Cell Lysate Lane 3: PANC Cell Lysate 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Human Kaninchen Unkonjugiert IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human bladder carcinoma labeled with Rabbit Anti LAMA2 Polyclonal Antibody, Unconjugated (ABIN1387552) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Human Maus Unkonjugiert IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to LAMA2 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 1 ug/ml] Detection limit for recombinant GST tagged LAMA2 is 1 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Human Maus Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
583,00 €
Human Maus Unkonjugiert IHC (p), ELISA, WB Human Placenta, Trophoblast: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
565,71 €
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €

LAMA2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Laminin Antikörper

  1. Human Polyclonal Laminin Primary Antibody für WB - ABIN3042862 : Chen, Wan, Xia, Guo, Wang, Liu, Li: Promoted regeneration of mature blood vessels by electrospun fibers with loaded multiple pDNA-calcium phosphate nanoparticles. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fu?r Pharmazeutische Verfahrenstechnik e.V 2013 (PubMed)
    Show all 13 Pubmed References

  2. Human Monoclonal Laminin Primary Antibody für IHC (p), ELISA - ABIN561638 : Lemons, Feng, Bennett, Legesse-Miller, Johnson, Raitman, Pollina, Rabitz, Rabinowitz, Coller: Quiescent fibroblasts exhibit high metabolic activity. in PLoS biology 2010 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen Laminin Interaktionspartner

Zebrafish Laminin, alpha 2 (LAMA2) Interaktionspartner

  1. analysis of the caf zebrafish model of MDC1A, which has a mutation in LAMA2

  2. The degenerative muscle phenotype in the zebrafish dystrophic mutant, candyfloss (caf) results from mutations in the laminin alpha2 (lama2) gene.

Human Laminin, alpha 2 (LAMA2) Interaktionspartner

  1. Differential protein expression of collagen IV (zeige COL4 Antikörper), laminin alpha2, and nidogen-1 (zeige NID1 Antikörper) indicated basal lamina remodeling develops in ischemic failing versus nonfailing human hearts.

  2. Next generation sequencing was found to be useful for molecular diagnosis of a confirmed case of merosin deficient congenital muscular dystrophy.

  3. did not find positive association signals of the four single nucleotide polymorphisms in the LAMA2 and EGR1 (zeige EGR1 Antikörper) genes with high myopia

  4. By analyzing the gene test we found that compound heterozygous LAMA2 mutation inherited from the parents. One coming from the father was a gross deletion expanding from exon 36 to exon 65. The from the mother was a missense mutation c.1358G>C

  5. This report widens the clinical spectrum of cerebral manifestations related with mutations in LAMA2

  6. Data showed miR (zeige MLXIP Antikörper)-29a/c as novel regulators of LAMA2 in ependymoma based on miRNA-mRNA covariation and sequence-based target predictions.

  7. This study demonstrates a wide clinical spectrum of LAMA2-related muscular dystrophy and its prevalence in an LGMD2 (zeige CAPN3 Antikörper) cohort, which indicates that LAMA2 muscular dystrophy should be included in the LGMD2 (zeige CAPN3 Antikörper) nomenclature.

  8. Crystal structure of LAMM L4 domain

  9. Data find high frequency mutations in LAMA2 protein in hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) patients. Its lower expression levels correlate with tumor progression, poor survival and higher chance of cancer recurrence.

  10. 2 patients with partial laminin-alpha2 deficiency and atypical phenotypes, one with almost exclusive central nervous system involvement and second with cardiac dysfunction, rigid spine syndrome and limb-girdle weakness; both have 2 heterozygous LAMA2 variants sharing a potentially pathogenic missense mutation c.2461A>C located in exon 18

Mouse (Murine) Laminin, alpha 2 (LAMA2) Interaktionspartner

  1. Data show that laminin alpha2beta1gamma1 (Lm211) can inhibit neuregulin 1 (zeige NRG1 Antikörper) type III (Nrg1III) by limiting protein kinase A (PKA) activation, which is required to initiate myelination.

  2. results indicate a novel role for laminin-dystroglycan interactions in the cooperative integration of astrocytes, endothelial cells, and pericytes in regulating the Blood Brain Barrier.

  3. Laminin alpha2-mediated FAK (zeige PTK2 Antikörper) activation in podocytes is an important early event in Alport glomerular pathogenesis.

  4. The effects of merosin knockout on alkaline phosphatase activity in the liver of normal and dystrophic mice is reported.

  5. The data of this study suggested that prosurvival Lama (zeige LAMA1 Antikörper) interactions in the developing postnatal VZ-SVZ germinal zone regulate the ability, or timing, of oligodendrocyte production to occur appropriately.

  6. Levels of both lipid rafts and raft-located acetylcholinesterase (zeige AChE Antikörper) dimers increase in muscle of mice with muscular dystrophy by merosin deficiency.

  7. Overexpression of laminin alpha1 chain that lacks the dystroglycan binding LG4-5 domains in alpha2 chain deficient mice resulted in prolonged lifespan and improved health.

  8. Ku70 (zeige XRCC6 Antikörper) is a regulator of Bax (zeige BAX Antikörper)-mediated pathogenesis in laminin-alpha2-deficiency muscle cells.

  9. this study identified a novel spontaneous mouse model of human congenital muscular dystrophy with laminin alpha2 chain deficiency, named dy(Pas (zeige PASK Antikörper))/dy(Pas (zeige PASK Antikörper)). Homozygous animals rapidly developed a progressive muscular dystrophy leading to premature death.

  10. merosin contributes to muscle passive stiffness, viscoelasticity, and contractility

Laminin (LAMA2) Antigen-Profil

Protein Überblick

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Genbezeichner und Symbole assoziert mit LAMA2

  • laminin, alpha 2 (LAMA2) Antikörper
  • laminin, alpha 2 (lama2) Antikörper
  • laminin, alpha 2 (Lama2) Antikörper
  • 5830440B04 Antikörper
  • dy Antikörper
  • LAMA2 Antikörper
  • LAMM Antikörper
  • mer Antikörper
  • merosin Antikörper
  • mKIAA4087 Antikörper

Bezeichner auf Proteinebene für LAMA2

laminin alpha 2 subunit , laminin, alpha 2 (merosin, congenital muscular dystrophy) , laminin, alpha 2 , caf , candyfloss , laminin alpha 2 chain , unm teg15a , unm tk209 , laminin subunit alpha-2-like , laminin M chain , laminin subunit alpha-2 , laminin-12 subunit alpha , laminin-2 subunit alpha , laminin-4 subunit alpha , merosin heavy chain , dystrophia muscularis

472122 Pan troglodytes
484121 Canis lupus familiaris
100049705 Danio rerio
100405831 Callithrix jacchus
100460380 Pongo abelii
100484712 Ailuropoda melanoleuca
100545053 Meleagris gallopavo
100565785 Anolis carolinensis
100583654 Nomascus leucogenys
3908 Homo sapiens
100350500 Oryctolagus cuniculus
16773 Mus musculus
309368 Rattus norvegicus
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