Kruppel-Like Factor 5 (Intestinal) Proteine (KLF5)

KLF5 encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Zusätzlich bieten wir Ihnen KLF5 Antikörper (70) und KLF5 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte KLF5 KLF5 84410  
KLF5 12224 Q9Z0Z7
KLF5 688 Q13887
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 10 bis 15 Tage
246,67 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
617,14 €
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KLF5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Kruppel-Like Factor 5 (Intestinal) (KLF5) Interaktionspartnern

Mouse (Murine) Kruppel-Like Factor 5 (Intestinal) (KLF5) Interaktionspartner

  1. In conclusion, the results of this study suggest that the presence of KLF5 in postn (zeige POSTN Proteine)-positive cells contributes to the pathogenesis of aortic thickening induced by DOCA-salt hypertension.

  2. these studies demonstrate dual functions of Klf5 in regulating hematopoietic stem and progenitor proliferation and localization in the bone marrow, as well as lineage choice after GMP (zeige NT5C2 Proteine), promoting increased neutrophil output at the expense of eosinophil production.

  3. Collectively, we identify a novel regulatory pathway in which 1, 25(OH)2D3 induces VDR (zeige CYP27B1 Proteine) expression and promotes VDR (zeige CYP27B1 Proteine) interaction with p50 subunit of NF-kappaB (zeige NFKB1 Proteine), which in turn attenuates the association of KLF5 with p50 subunit of NF-kappaB (zeige NFKB1 Proteine) and thus exerts anti-inflammatory and anti-proliferative effects on macrophages.

  4. KLF5-dependent regulation of Myo9b/RhoA (zeige RHOA Proteine) is required for podosome formation and macrophage migration during abdominal aortic aneurysm.

  5. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  6. illustrates that KLF5 may modulate DNA repair pathways to prevent intestinal injury induced by TBI. KLF5 signaling provides a novel field for identification of potential therapeutic targets for the treatment of radiation-induced intestinal damage

  7. Cardiac myocyte KLF5 is a transcriptional regulator of Ppara (zeige PPARA Proteine) and cardiac energetics.

  8. In embryonic stem cells, we show that Klf5, but not JunB (zeige JUNB Proteine) is a key LIF (zeige LIF Proteine) effector of cell plasticity.

  9. the regulatory functions of Klf5 acetylation in ESC self-renewal and differentiation

  10. unravels a novel mechanism how matrix stiffness regulates cellular proliferation and highlights the importance of matrix stiffness-modulated Klf5/Klf4 (zeige KLF4 Proteine) in the regulation of renal physiologic functions and fibrosis progression

Human Kruppel-Like Factor 5 (Intestinal) (KLF5) Interaktionspartner

  1. miR (zeige MLXIP Proteine)-217 suppresses triple-negative breast cancer cell growth, migration, and invasion. MiR (zeige MLXIP Proteine)-217 suppresses triple-negative breast cancer, at least partially, through down-regulating the KLF5 expression.

  2. Data reveal that the presence of rs200996365, a SNP in high-linkage disequilibrium with rs8102137 residing in the center of a KLF5 motif, alters KLF5 binding to this genomic region and provide evidence that KLF5 binds CCNE1 (zeige CCNE1 Proteine) polymorphic intronic enhancer to confer increased bladder cancer risk.

  3. demonstrate that a 186bp region is the minimal essential region and that Sp3-GC1 (zeige OLFM4 Proteine) binding is essential to the basal expression of KLF5

  4. We provide the first evidence that the expression of KLF5 is up-regulated in small airways and pulmonary vessels of patients with COPD (zeige ARCN1 Proteine) and may be involved in the tissue remodeling of COPD (zeige ARCN1 Proteine).

  5. our results indicate that KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA (zeige VEGFA Proteine) transcription

  6. Data indicate direct binding of microRNA miR (zeige MLXIP Proteine)-375 to the 3'-untranslated region of transcription factor KLF5.

  7. findings collectively suggest that TNFAIP2 (zeige TNFAIP2 Proteine) is a direct KLF5 target gene, and both KLF5 and TNFAIP2 (zeige TNFAIP2 Proteine) promote breast cancer cell proliferation, migration and invasion through Rac1 and Cdc42 (zeige CDC42 Proteine)

  8. ABL (zeige ABL1 Proteine)-N administration induced apoptosis of PC3 (zeige PCSK1 Proteine) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (zeige BAX Proteine)/Bcl-2 (zeige BCL2 Proteine) ratio. Expression of KLF5, Stat5b (zeige STAT5B Proteine) and ICAM-1 (zeige ICAM1 Proteine) was significantly downregulated in PC3 (zeige PCSK1 Proteine) cells.

  9. KLF5/Sox4 regulatory signaling play an important role in lung tumorigenesis, which might represent novel therapeutic targets to manage lung carcinoma.

  10. BAP1 (zeige RNF2 Proteine) interacts directly with KLF5 and stabilizes KLF5 via deubiquitination.

KLF5 Protein Überblick

Protein Überblick

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

Genbezeichner und Symbole assoziert mit KLF5

  • Kruppel-like factor 5 (intestinal) (KLF5)
  • Kruppel-like factor 5 (intestinal) (LOC100231095)
  • Kruppel-like factor 5 (klf5)
  • Kruppel-like factor 5 (Klf5)
  • 4930520J07Rik Protein
  • bteb2 Protein
  • CKLF Protein
  • IKLF Protein
  • klf5 Protein
  • MGC115081 Protein

Bezeichner auf Proteinebene für KLF5

Kruppel-like factor 5 (intestinal) , Krueppel-like factor 5-like , Kruppel-like factor 5 , basic-transcription-element-binding-protein 2 , basic transcription element binding protein 2 , basic transcription element binding protein BTEB2 , BTE-binding protein 2 , Krueppel-like factor 5 , basic transcription element-binding protein 2 , intestinal-enriched krueppel-like factor , transcription factor BTEB2 , GC box binding protein 2 , GC-box-binding protein 2 , colon krueppel-like factor , colon kruppel-like factor , intestinal-enriched kruppel-like factor

GENE ID SPEZIES
100052058 Equus caballus
452597 Pan troglodytes
100010455 Monodelphis domestica
100231095 Taeniopygia guttata
100467044 Ailuropoda melanoleuca
100607414 Nomascus leucogenys
735138 Xenopus laevis
100008718 Oryctolagus cuniculus
84410 Rattus norvegicus
12224 Mus musculus
688 Homo sapiens
418818 Gallus gallus
612788 Canis lupus familiaris
100038005 Sus scrofa
535702 Bos taurus
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