Keratin 19 Proteine (KRT19)

The protein encoded by KRT19 is a member of the keratin family. Zusätzlich bieten wir Ihnen Keratin 19 Antikörper (904) und Keratin 19 Kits (41) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
KRT19 3880 P08727
KRT19 360626 Q63279
KRT19 16669 P19001
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Top Keratin 19 Proteine auf

Showing 10 out of 28 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
303,81 €
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
218,90 €
HOST_Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
438,90 €
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 10 bis 13 Tage
322,10 €
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
HOST_Escherichia coli (E. coli) Maus His tag   100 μg Anmelden zum Anzeigen 13 bis 17 Tage
533,33 €
Hefe Mesocricetus auratus His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.100,48 €

KRT19 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , ,
Rat (Rattus)

Mouse (Murine)

Am meisten referenzierte Keratin 19 Proteine

  1. Human KRT19 Protein expressed in Escherichia coli (E. coli) - ABIN1098759 : Leelawat, Narong, Udomchaiprasertkul, Wannaprasert, Treepongkaruna, Subwongcharoen, Ratanashu-ek: Prognostic relevance of circulating CK19 mRNA in advanced malignant biliary tract diseases. in World journal of gastroenterology : WJG 2012 (PubMed)
    Zeige alle 2 Referenzen für 1098759

Weitere Proteine zu Keratin 19 (KRT19) Interaktionspartnern

Human Keratin 19 (KRT19) Interaktionspartner

  1. Data suggest that keratin (K) 19 (K19) may be a drug target for the treatment of K19-positive hepatocellular carcinoma (HCC (zeige FAM126A Proteine)).

  2. Combination of the two tumor markers, CEA (zeige CEACAM5 Proteine) and CYFRA21-1, is a predictive and prognostic marker of docetaxel monotherapy for previously treated NSCLC patients

  3. Results suggest that positive expression of CK19 mRNA and TK1 (zeige TK1 Proteine) protein is closely correlated with poor prognosis in advanced gastrointestinal cancer.

  4. GPC3 (zeige GPC3 Proteine) and KRT19 overexpression are associated with carcinogenesis, progression, and poor prognosis in patients with PDAC and a valuable biomarker for diagnosis of PDAC.

  5. Data show that sixty one patients with a high cytokeratin 19 fragment (CYFRA 21-1) level had statistically shorter progression-free and overall survival than 39 patients with a normal CYFRA 21-1 level .

  6. Data indicate that serum tumor markers showed significant shorter 3-year progression-free survival (PFS) in higher levels compared to lower levels for S-CYFRA 21-1 (cytokeratin 19 fragment), S-SCCA and S-CEA (zeige CEACAM5 Proteine).

  7. Gene promoter hypermethylation is found in sentinel lymph nodes of breast cancer patients identified as positive by one-step nucleic acid amplification of cytokeratin 19 mRNA

  8. Peritumoral ductular reaction was more abundant and proliferative in CK19+ hepatocellular carcinoma patients, with higher level of nuclear translocation of beta-catenin (zeige CTNNB1 Proteine).

  9. BALF and serum NSE (zeige ENO2 Proteine), CEA (zeige CEACAM5 Proteine), and CYFRA21.1 elevated in lung cancer, which had prompt value for pathology, especially significant for BALF.

  10. Significant levels of CEA (zeige CEACAM5 Proteine), CYFRA 21-1, NSE (zeige ENO2 Proteine), and TSGF were detected in the serum. The amounts found were useful for diagnosing non-small cell lung cancer (NSCLC) patients who depended on the currently limited biomarker development.

Mouse (Murine) Keratin 19 (KRT19) Interaktionspartner

  1. Demonstrate that K19 plays an important role in the ductular reaction that constitutes the basic regenerative response to chronic liver injury.

  2. Branched desmin (zeige DES Proteine)-deficient (DKO) myofibers show significantly faster rates of calcium ion (Ca2 (zeige CA2 Proteine)+) clearance, with milder branching phenotype observed in DKO muscle suggesting that absence of keratin-19 corrects the defect created by absence of desmin (zeige DES Proteine) alone.

  3. the structural response of each genotype is distinct, suggesting multiple mechanisms by which desmin and keratin influence the biomechanical properties of myofibers

  4. The expression of CK19 and EGFR (zeige EGFR Proteine) in lymphatic metastasis of laryngeal carcinoma was higher than in controls.

  5. Results suggest that keratin filaments containing K19- and desmin (zeige DES Proteine)-based intermediate filaments can play independent, complementary, or antagonistic roles in the physiology and morphology of fast-twitch skeletal muscle.

  6. a dual mechanism of how PDX-1 (zeige PDX1 Proteine) negatively regulates Krt19 ductal specific gene expression

  7. expression of nestin (zeige NES Proteine) and cytokeratin 19 is a normal property of embryonic stem cells preceding differentiation into C-peptide/insulin (zeige INS Proteine)-producing cells without any selection for nestin (zeige NES Proteine)-positive phenotypes

  8. loss of the keratin cytoskeleton causes defects in the trophoblast giant cell layer

  9. transduction of PDX1 (zeige PDX1 Proteine) in primary pancreatic ductal cells suppresses K19 expression, and short interfering RNA to PDX1 (zeige PDX1 Proteine) in Min6 insulinoma (zeige RPS15 Proteine) cells and results in the induction of normally undetectable K19

  10. This is the first demonstration of a mammalian phenotype associated with a genetic perturbation of keratin 19.

Keratin 19 (KRT19) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.

Genbezeichner und Symbole assoziert mit Keratin 19 Proteine (KRT19)

  • keratin 19 (KRT19)
  • keratin 19 (krt19)
  • keratin 19 (Krt19)
  • AI663979 Protein
  • CK19 Protein
  • EndoC Protein
  • GK-19 Protein
  • K1CS Protein
  • K19 Protein
  • Ka19 Protein
  • Krt-1.19 Protein
  • Krt1-19 Protein
  • krt9 Protein
  • krt15 Protein
  • KRT19 Protein
  • MGC76282 Protein
  • MGC83069 Protein

Bezeichner auf Proteinebene für Keratin 19 Proteine (KRT19)

keratin 19 , cytokeratin 22 (human cytokeratin 19) , keratin, type I cytoskeletal 19-like , 40-kDa keratin intermediate filament , CK-19 , cytokeratin 19 , cytokeratin-19 , keratin, type I cytoskeletal 19 , keratin, type I, 40-kd , keratin-19 , K19 , keratin complex 1, acidic, gene 19 , type I keratin KA19 , Keratin, type I cytoskeletal 19

281470 Bos taurus
394514 Xenopus (Silurana) tropicalis
432054 Xenopus laevis
454663 Pan troglodytes
100126186 Canis lupus familiaris
100398836 Callithrix jacchus
100587819 Nomascus leucogenys
3880 Homo sapiens
395861 Gallus gallus
514812 Bos taurus
360626 Rattus norvegicus
16669 Mus musculus
779233 Xenopus laevis
100685481 Canis lupus familiaris
100173010 Pongo abelii
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