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IL28B encodes a cytokine distantly related to type I interferons and the IL-10 family. Zusätzlich bieten wir Ihnen Interleukin 28B (Interferon, lambda 3) Antikörper (112) und Interleukin 28B (Interferon, lambda 3) Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.
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Human IL28B ELISA Kit für Sandwich ELISA - ABIN414558
Rallón, Soriano, Naggie, Restrepo, McHutchison, Vispo, Benito: Impact of IL28B gene polymorphisms on interferon-?3 plasma levels during pegylated interferon-?/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV. in The Journal of antimicrobial chemotherapy 2012
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Human IL28B ELISA Kit für Sandwich ELISA - ABIN457021
Khairy, Fouad, Mabrouk, El-Akel, Awad, Salama, Elnegouly, Shaker: The impact of interleukin 28b gene polymorphism on the virological response to combined pegylated interferon and ribavirin therapy in chronic HCV genotype 4 infected egyptian patients using data mining analysis. in Hepatitis monthly 2013
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results suggest that IL-28B induces more mature NK cells to defend against viruses, in addition to its direct antiviral activity
IL-28B down-regulates Tregs following subunit vaccine ESAT6-Ag85B-Mpt64(190-198)-Mtb8.4-HspX (zeige HSP ELISA Kits) vaccination but does not improve the protective immune responses.
the role of IFN-lambda in IDO (zeige IDO1 ELISA Kits) regulation was investigated after influenza infection of respiratory epithelial cells.
Data indicate that rotavirus infection induces production of interferon (zeige IFNA ELISA Kits)-lambda (IFN-lambda) and interleukin 22 (IL-22 (zeige IL22 ELISA Kits)) by intestinal epithelial cells.
Acritical role of IL-28 cytokines is in controlling T cell responses in vivo through the modulation of lung CD11c (zeige ITGAX ELISA Kits)(+) DC function in experimental allergic asthma.
IFN-alpha (zeige IFNA ELISA Kits), IFN-beta (zeige IFNB1 ELISA Kits), and IFN-gamma (zeige IFNG ELISA Kits) were observed in the anterior segment of injected eyes through 72 hours and mRNA levels of IFN-beta (zeige IFNB1 ELISA Kits) and IFN-gamma (zeige IFNG ELISA Kits) were increased in virus-infected eyes 48 to 120 hours after herpes simplex infection
the duration of IFNlambda signaling to JAK (zeige JAK3 ELISA Kits)/STAT (zeige STAT1 ELISA Kits) is different from that of IFNalpha
intranasal influenza A virus infection leads to the robust type III IFN induction in the lungs of both WT and IFNAR (zeige IFNAR1 ELISA Kits)-/- mice
IL-28A (zeige IL28A ELISA Kits) emerges as a key regulatory cytokine with pathogenic function in T-cell-mediated liver injury
Type III interferon (zeige IFNA ELISA Kits)/IL-28 targets a specific subset of cells and contributes to the antiviral response evoked by Toll (zeige TLR4 ELISA Kits)-like receptors, largely mediated by inducing an antiviral state in epithelial cells.
IL-28B rs12979860 SNP could be used as an independent predictor for treatment response among HCV patients.
In hemodialysis patients, circulating IFN-lambda3 strongly correlates with anti-HBs antibody production after HBV vaccination and infection. IFNL3 rs8099917 polymorphisms seem to be associated with IFN-lambda3 plasma levels in hemodialysis subjects.
Results demonstrated genetic variations of IL-28B might impact liver function recovery after transplantation by influencing peripheral platelet counts and reducing liver inflammation, but weak association with transplant etiologies.
The results obtained suggest that both studied IL28B gene SNPs (single nucleotide polymorphisms), as well as the IL10 (zeige IL10 ELISA Kits) gene rs1800872 SNP are associated with predisposition to tick-borne encephalitis in Russian population.
IL-28B genotyping may be useful for directing patients towards lower cost therapies, and rationing use of costly direct antivirals for use in those individuals showing genetic risk.
the IFNL3 rs 12979860 CC genotype may be negatively associated with hepatic steatosis in Asian chronic hepatitis C patients.
IL-28B rs12979860 genotype was significantly related to severe necroinflammatory activity (NIA) grade of chronic hepatitis C patients.
Data show that the genotype distributions of IFNL3 and IFNL4 variants (rs4803217, rs368234815, rs117648444, and rs12979860) were in Hardy-Weinberg equilibrium.
In Taiwan, chronic hepatitis C (CHC (zeige CLTC ELISA Kits)) patients have a lower frequency of favorable IL28B TT genotype than healthy controls. Among patients with CHC (zeige CLTC ELISA Kits), the frequency of TT genotype is higher in HCV genotype 2 patients than in HCV genotype 1 patients. In addition, CHC (zeige CLTC ELISA Kits) patients with TT genotype, particularly females, have a lower likelihood of advanced fibrosis.
IFNL3 SNPs genotyped have shown no association with ribavirin treatment in hepatitis C patients with genotype 3.
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
, interferon alpha
, interferon lambda-3
, interleukin 28
, cytokine Zcyto22
, interferon lambda-4
, interferon, lambda 4
, interleukin 28B (interferon, lambda 3)
, interleukin 28C