anti-Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) Antikörper

HPGD encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. Zusätzlich bieten wir Ihnen HPGD Proteine (18) und HPGD Kits (17) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HPGD 15446 Q8VCC1
HPGD 79242 O08699
HPGD 3248 P15428
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Top anti-HPGD Antikörper auf antikoerper-online.de

Showing 10 out of 126 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of HPGD Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). HPGD (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded mouse placenta, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-Prostaglandin dehydrogenase 1 Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary for 90 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
315,94 €
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB ABIN250327 (0.1µg/ml) staining of Human Duodenum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescenc Western Blot: 15-PGDH/HPGD Antibody [ABIN250327] - Anaylsis of 15-PGDH in Human Duodenum lysate using ABIN250327 at 0.1ug/ml. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (fro), IHC (p), SimWes, WB Simple Western: 15-PGDH/HPGD Antibody [ABIN152315] - Simple Western lane view shows a specific band for 15-PGDH/HPGD in 0.5 mg/ml of Lovo (left) and HeLa (right) lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185316 (0.1µg/ml) staining of Human Duodenum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of HPGD Antibody (C-term) (ABIN390765) in MDA-MB231 cell line lysates (35 µg/lane). HPGD (arrow) was detected using the purified polyclonal antibody. HPGD Antibody (C-term) (ABIN390765) IHC analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-HPGD AntibodyTitration: 1.0 µg/mL  Positive Control: MDA-MB-435S Whole Cell 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 18 bis 20 Tage
250,00 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: HPGD Antibody [NBP1-87062] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17.Lane 2: Human cell line RT-4 Immunocytochemistry/Immunofluorescence: HPGD Antibody [NBP1-87062] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli & cytoplasm. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Maus Unkonjugiert FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HPGD (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HPGD. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
366,67 €
Details

HPGD Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-HPGD Antikörper

  1. Human Polyclonal HPGD Primary Antibody für ICC, IF - ABIN152315 : Giannoulias, Patel, Holloway, Lye, Tai, Challis: Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium. in The Journal of clinical endocrinology and metabolism 2002 (PubMed)
    Zeige alle 24 Referenzen für 152315

  2. Human Monoclonal HPGD Primary Antibody für ELISA - ABIN1998443 : Patel, Funder, Challis et al.: Mechanism of cortisol/progesterone antagonism in the regulation of 15-hydroxyprostaglandin dehydrogenase activity and messenger ribonucleic acid levels in human chorion and placental trophoblast ... in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Zeige alle 3 Referenzen für 1998443

  3. Human Polyclonal HPGD Primary Antibody für IHC, IHC (p) - ABIN4319762 : Wu, Hsu, Chen, Yu, Chang, Tai, Liu, Su, Chang, Yu: Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas. in Molecular & cellular proteomics : MCP 2010 (PubMed)
    Zeige alle 2 Referenzen für 4319762

  4. Human Polyclonal HPGD Primary Antibody für ELISA, WB - ABIN185316 : Coggins, Latour, Nguyen, Audoly, Coffman, Koller: Metabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosus. in Nature medicine 2002 (PubMed)
    Zeige alle 2 Referenzen für 185316

  5. Human Polyclonal HPGD Primary Antibody für IF (p), IHC (p) - ABIN761711 : Wei, Yu, Shi, Zhang, Lian, Li, Shen, Xing, Zhu: 15-PGDH/15-KETE plays a role in hypoxia-induced pulmonary vascular remodeling through ERK1/2-dependent PAR-2 pathway. in Cellular signalling 2014 (PubMed)
    Zeige alle 2 Referenzen für 761711

  6. Human Polyclonal HPGD Primary Antibody für EIA, WB - ABIN453113 : Thill, Fischer, Becker, Cordes, Dittmer, Diedrich, Salehin, Friedrich: Prostaglandin metabolizing enzymes in correlation with vitamin D receptor in benign and malignant breast cell lines. in Anticancer research 2009 (PubMed)

Weitere Antikörper gegen HPGD Interaktionspartner

Mouse (Murine) Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) Interaktionspartner

  1. 15-PGDH prevents lipopolysaccharide-induced acute liver injury in mice.

  2. the protein level of 15-hydroxyprostaglandin dehydrogenase (15-PGDH), a key enzyme in prostaglandin metabolism, in Amyotrophic lateral sclerosis model mice at three different disease stages, was investigated.

  3. 15-PGDH is downregulated in human hepatoma cells with a high COX-2 (zeige COX2 Antikörper) expression, in chemical and genetic murine models of hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) and in human HCC (zeige FAM126A Antikörper) biopsies.

  4. Data from a mouse model suggest that expression of Hpgd protein in uterus is down-regulated in lipopolysaccharide/infection-induced embryo loss.

  5. prostaglandin E synthase (zeige PTGES Antikörper) (cPGES/p23 (zeige PTGES3 Antikörper)) acts as a regulatory factor for expression of a prostaglandin E2 -inactivating enzyme,15-hydroxyprostaglandin dehydrogenase ( 15-PGDH).

  6. I. sinclarii is effective in lowering blood glucose due to the upregulation of glucokinase (Gk (zeige GCK Antikörper)-rs1 (zeige RS1 Antikörper)) and downregulation of hydroxyprostaglandin dehydrogenase.

  7. OAT (zeige OAT Antikörper)-PG is proposed to be involved in the local PGE (zeige LIPF Antikörper)(2) clearance and metabolism for the inactivation of prostaglandin signals in the kidney cortex.

  8. novel tumor suppressive role for 15-PGDH due to loss of expression during colorectal tumor progression

  9. 15-Hydroxyprostaglandin dehydrogenase (zeige CBR1 Antikörper) has a role in suppressing colon tumorigenesis

  10. The intrarenal distribution of 15-PGDH and its interactions with COX-2 (zeige COX2 Antikörper) suggest that differential regulation of COX-2 (zeige COX2 Antikörper) and 15-PGDH plays a role in determining levels of prostaglandins involved in regulation of salt, volume, and blood pressure homeostasis.

Guinea Pig Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) Interaktionspartner

  1. Data indicate that 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor TD88 could be a good effector on wound healing, especially in the aspects of prevention of scarring.

  2. The data indicate that decreased expression of 15-hydroxyprostaglandin dehydrogenase in the fetal membranes may contribute to the increase in intrauterine prostaglandin concentrations at term, stimulating the onset of labor.

Human Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD) Interaktionspartner

  1. inhibitory effects of 17-AAG (zeige MPG Antikörper) on PGE2 levels in HT-29 colorectal cancer cells were mediated through modulating COX-2 (zeige COX2 Antikörper) and 15-PGDH expression.

  2. A common mutation and a novel mutation in HPGD gene were identified to be responsible for primary hypertrophic osteoarthropathy

  3. Peroxisome proliferator-activated receptors (PPARs) play pivotal roles in maintenance of Chorionic NAD-dependent 15-hydroxy prostaglandin dehydrogenase (PGDH) expression in chorion during human pregnancy.

  4. Neoadjuvant chemotherapy could increase 15-PGDH expression in advanced gastric cancer patients, and 15-PGDH may serve as a candidate prognostic biomarker of advanced GC response to therapy.

  5. 15-PGDH mRNA levels were significantly higher in aorta samples from patients undergoing abdominal aortic aneurysm repair than in those from healthy multiorgan donors.

  6. Omega-3 polyunsaturated fatty acids upregulate the expression of 15-PGDH by inhibiting miR (zeige MLXIP Antikörper)-26a and miR (zeige MLXIP Antikörper)-26b.

  7. Multiple drug resistance-associated protein (zeige ABCC1 Antikörper) 4 (MRP4 (zeige ABCC4 Antikörper)), prostaglandin transporter (PGT (zeige SLCO2A1 Antikörper)), and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as determinants of PGE2 levels in cancer.

  8. Loss of PGDH expression is associated with esophageal squamous cell carcinoma and adenocarcinoma.

  9. A single nucleotide polymorphism in the 3' untranslated region (UTR (zeige UTS2R Antikörper)) of the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene modifies mir (zeige MLXIP Antikörper)-485-5p binding in breast cancer.

  10. Case Reports: novel 2 (zeige TSPAN4 Antikörper)-bp homozygous deletion was found in exon 3 (c.310-311delCT) of HPGD gene in the patients with Primary hypertrophic osteoarthropathy.

HPGD Antigen-Profil

Protein Überblick

This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit HPGD

  • hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) Antikörper
  • hydroxyprostaglandin dehydrogenase 15-(NAD) (hpgd) Antikörper
  • 15-hydroxyprostaglandin dehydrogenase (pgdh) Antikörper
  • 15-hydroxyprostaglandin dehydrogenase (PTRG_03214) Antikörper
  • 15-hydroxyprostaglandin dehydrogenase (VDBG_09957) Antikörper
  • hydroxyprostaglandin dehydrogenase 15 (NAD) (Hpgd) Antikörper
  • 15-PGDH Antikörper
  • AV026552 Antikörper
  • MGC79454 Antikörper
  • MGC80546 Antikörper
  • PGDH Antikörper
  • PGDH1 Antikörper
  • PHOAR1 Antikörper
  • SDR36C1 Antikörper

Bezeichner auf Proteinebene für HPGD

15-hydroxyprostaglandin dehydrogenase , hydroxyprostaglandin dehydrogenase 15-(NAD) , 15-hydroxyprostaglandin dehydrogenase [NAD(+)] , PGDH , prostaglandin dehydrogenase 1 , 15-PGDH , NAD-dependent 15-hydroxyprostaglandin dehydrogenase , 15-hydroxyprostaglandin dehydrogenase (NAD+) , NAD+-dependent 15-hydroxyprostaglandin dehydrogenase , short chain dehydrogenase/reductase family 36C, member 1 , NAD+ dependent 15-hydroxyprostaglandin dehydrogenase

GENE ID SPEZIES
422567 Gallus gallus
446811 Xenopus laevis
461613 Pan troglodytes
486073 Canis lupus familiaris
493354 Xenopus (Silurana) tropicalis
100009687 Equus caballus
100156186 Sus scrofa
100172788 Pongo abelii
100196521 Salmo salar
6341441 Pyrenophora tritici-repentis Pt-1C-BFP
9531736 Verticillium alfalfae VaMs.102
15446 Mus musculus
79242 Rattus norvegicus
100135538 Cavia porcellus
3248 Homo sapiens
512259 Bos taurus
101112958 Ovis aries
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