GTP Binding Protein 3 (Mitochondrial) (GTPBP3) ELISA Kits

This locus encodes a GTP-binding protein. Zusätzlich bieten wir Ihnen GTPBP3 Antikörper (33) und GTPBP3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GTPBP3 290633 Q5PQQ1
GTPBP3 70359 Q923K4
GTPBP3 84705 Q969Y2
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Top GTPBP3 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Menge Anbieter Lieferzeit Preis Details
Human
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Maus
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Ratte
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Weitere ELISA Kits für GTPBP3 Interaktionspartner

Mouse (Murine) GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Interaktionspartner

  1. These observations suggest that the mouse Gtpbp3 is an evolutionarily conserved mitochondrial GTP-binding protein involved in the tRNA modification.

Human GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Interaktionspartner

  1. GTPBP3 defective expression is associated with an mitochondrial-tRNA hypomodification status.GTPBP3 plays a role in the regulation of UCP2 (zeige UCP2 ELISA Kits) and MCP1 (zeige CCL2 ELISA Kits) proteins through AMPK (zeige PRKAA1 ELISA Kits) signaling.

  2. Results show that post-transcriptional expression of GTPBP3, MTO1 and TRMU (zeige TRMU ELISA Kits) genes is down-regulated, leading to mt-tRNA hypomodification and contributing to mitochondrial dysfunction in MELAS cybrids.

  3. Most individuals with GTPBP3 mutations developed neurological symptoms and MRI (zeige C7ORF49 ELISA Kits) involvement of thalamus, putamen, and brainstem resembling Leigh syndrome.

  4. GTPBP3 localizes in the mitochondria and is a deafness-associated homolog of yeast MSS1.

  5. Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3.

  6. Data show that the two most abundant GTPBP3 isoforms exhibit moderate affinity for guanine nucleotides like their bacterial homologue, MnmE, although they hydrolyze GTP (zeige AK3 ELISA Kits) at a 100-fold lower rate.

GTPBP3 Antigen-Profil

Beschreibung des Gens

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit GTPBP3

  • GTP binding protein 3 (mitochondrial) (GTPBP3) Antikörper
  • GTP binding protein 3 (Gtpbp3) Antikörper
  • GTP binding protein 3 (gtpbp3) Antikörper
  • 2410009F13Rik Antikörper
  • AI607903 Antikörper
  • GTPBG3 Antikörper
  • GTPBP3 Antikörper
  • MSS1 Antikörper
  • MTGP1 Antikörper
  • THDF1 Antikörper
  • zgc:112394 Antikörper

Bezeichner auf Proteinebene für GTPBP3

GTP binding protein 3 (mitochondrial) , tRNA modification GTPase GTPBP3, mitochondrial , tRNA modification GTPase GTPBP3, mitochondrial-like , GTP-binding protein 3 , mitochondrial GTP-binding protein 1

GENE ID SPEZIES
484838 Canis lupus familiaris
539656 Bos taurus
100070158 Equus caballus
100392904 Callithrix jacchus
100474937 Ailuropoda melanoleuca
290633 Rattus norvegicus
553807 Danio rerio
70359 Mus musculus
84705 Homo sapiens
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