Enolase 1, (Alpha) Proteine (ENO1)

ENO1 encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Zusätzlich bieten wir Ihnen Enolase 1, (Alpha) Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Human ENO1 ENO1 2023 P06733
Ratte ENO1 ENO1 24333 P04764
Maus ENO1 ENO1 13806 P17182
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Weitere Proteine zu Enolase 1, (Alpha) (ENO1) Interaktionspartnern

Human Enolase 1, (Alpha) (ENO1) Interaktionspartner

  1. ENO1 promotes in pancreatic ductal adenocarcinoma (PDA) cells cell survival, migration, and metastasis through cooperation with integrins and uPAR (zeige PLAUR Proteine)

  2. ENO1 is a potent promoter of colorectal cancer genesis and metastasis at least in part though regulating AMPK (zeige PRKAA1 Proteine)/mTOR (zeige FRAP1 Proteine) pathway.

  3. comparing the T cell receptor repertoire of ENO1-specific peripheral and infiltrating tumor T cells from the same patient suggests that ENO1-specific T cells, despite having a different functional profile, can recirculate from the tumor to the periphery.

  4. ENO1 is able to activate in vitro the CD14 (zeige NDUFA2 Proteine)-dependent TLR4 (zeige TLR4 Proteine) pathway on monocytes involving a dual mechanism firstly pro-inflammatory and secondly anti-inflammatory.

  5. High ENO1 expression is associated with cancer.

  6. An immune-modulatory role has been proposed for surface alpha-enolase and our findings of decreased expression suggest that deficits in surface alpha-enolase merit investigation in the context of immune dysfunction during ageing and vascular disease

  7. Systems biology approach reveals possible evolutionarily conserved moonlighting functions for enolase

  8. ENO1 was demonstrated to be up-regulated by HIF-1alpha in retinal pigment epithelial cells in response to hypoxia, without influencing VEGF secretion.

  9. In this study, ENO1 silencing significantly reduced cell glycolysis, proliferation, migration, and invasion in vitro, as well as tumorigenesis and metastasis in vivo by modulating p85 suppression.

  10. alpha-Enolase increases after injury and may activate pulmonary endothelial cells and prime PMNs through plasmin (zeige PLG Proteine) activity and PAR-2 (zeige F2RL1 Proteine) activation

Cow (Bovine) Enolase 1, (Alpha) (ENO1) Interaktionspartner

  1. ENO1, VDAC2 (zeige VDAC2 Proteine), and UQCRC2 (zeige UQCRC2 Proteine) were significantly correlated with individual fertility in bulls.

Mouse (Murine) Enolase 1, (Alpha) (ENO1) Interaktionspartner

  1. Eno1 may be a potential marker for low sperm motility induced by iron ion radiation, and these results may provide a useful reference for changes in astronaut fertility during long space missions.

  2. The results confirmed the altered expression of HFABP (zeige FABP3 Proteine), a key fatty acid transport protein (zeige CD36 Proteine), and of enolase and PGK1 (zeige PGK1 Proteine), the key enzymes in the glycolytic process

  3. Pre-immunization with ENO1 or its immunodominant peptide pEP1 (zeige CNDP2 Proteine) reduces CIA (zeige NCOA5 Proteine) severity at the clinical, immunological and histological levels

  4. a Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine)-driven functional role of ENO1 and PDIA3 (zeige PDIA3 Proteine) in alveolar epithelial cell plasticity in lung injury and repair, is reported.

  5. Enolase is a new target of liver X receptors.

  6. Alpha-enolase is upregulated on the cell surface and responds to plasminogen (zeige PLG Proteine) activation in mice expressing a 133p53alpha mimic

  7. MBP1 inhibits Ab fibril formation in vitro and demonstrate the ability of MBP1 to reduce Ab pathology and improve behavioral performance.

  8. These data show a multiantibody composition in lupus nephritis, where IgG2 autoantibodies against alpha-enolase and annexin AI predominate in the glomerulus and can be detected in serum.

  9. These results demonstrate the novel requirement of alpha-enolase for restoring homeostasis of injured muscle tissue, by controlling the pericellular localization of plasmin (zeige PLG Proteine) activity.

  10. ENO1-positive monocytes and macrophages are found in arthritic ankle tissues of mice with collagen-induced arthritis.

Enolase 1, (Alpha) (ENO1) Protein Überblick

Protein Überblick

This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.

Genbezeichner und Symbole assoziert mit Enolase 1, (Alpha) Proteine (ENO1)

  • enolase 1 (eno1)
  • enolase 1 (ENO1)
  • Alpha-enolase (enoa)
  • enolase 1, (alpha) (Eno1)
  • enolase (LOC100499608)
  • enolase 1 S homeolog (eno1.S)
  • enolase 1, (alpha) (ENO1)
  • enolase 1 (Eno1)
  • enolase 1, alpha non-neuron (Eno1)
  • enolase 1a, (alpha) (eno1a)
  • 0610008I15 Protein
  • AL022784 Protein
  • Eno-1 Protein
  • eno1 Protein
  • eno1b Protein
  • eno1l1 Protein
  • MBP-1 Protein
  • mpb1 Protein
  • Nne Protein
  • pENO1 Protein
  • Pgh1 Protein
  • pph Protein
  • wu:fi32b03 Protein
  • wu:fk58e02 Protein
  • zgc:73152 Protein

Bezeichner auf Proteinebene für Enolase 1, (Alpha) Proteine (ENO1)

2-phospho-D-glycerate hydro-lyase 1 , 2-phosphoglycerate dehydratase 1 , enolase , enolase 1 , alpha-enolase , 2-phospho-D-glycerate hydro-lyase , NNE , non-neural enolase , Alpha-enolase , MYC promoter-binding protein 1 , alpha enolase like 1 , enolase-alpha , phosphopyruvate hydratase , plasminogen-binding protein , tau-crystallin , 2-phosphoglycerate dehydratase , enolase 1 b (alpha) , HAP47 , alpha enolase , enolase 1, alpha non-neuron , 2-phospho-D-glycerate hydrolase , c-Myc promoter binding protein , enolase 1, (alpha)

732811 Zea mays
457913 Pan troglodytes
100173448 Pongo abelii
100194865 Salmo salar
100306968 Cavia porcellus
100499608 Oncorhynchus mykiss
709378 Macaca mulatta
2023 Homo sapiens
380298 Xenopus laevis
396017 Gallus gallus
479597 Canis lupus familiaris
281141 Bos taurus
24333 Rattus norvegicus
406872 Sus scrofa
13806 Mus musculus
334116 Danio rerio
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