anti-Cystatin E/M (CST6) Antikörper

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Zusätzlich bieten wir Ihnen CST6 Proteine (16) und CST6 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CST6 1474 Q15828
CST6 73720  
CST6 171096  
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Top anti-CST6 Antikörper auf antikoerper-online.de

Showing 10 out of 90 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-Cst6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Mouse Spleen WB Suggested Anti-Cst6 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Mouse Spleen 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Cystatin E/M staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Cystatin E/M expression in HEK293T (A), PC12 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Maus Kaninchen Unkonjugiert ELISA, IHC (p) Immunochemical staining of mouse CST6 in mouse skin with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
250,00 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extract of various cells, using CST6 antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Maus Unkonjugiert IHC (p) Immunochemical staining of human CST6 in human skin with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
250,00 €
Details
Human Kaninchen Unkonjugiert WB Western Blot showing Cst6 antibody used at a concentration of 1-2 ug/ml to detect its target protein. 50 μg Anmelden zum Anzeigen 10 bis 13 Tage
460,89 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
443,50 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC   100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Maus Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 18 bis 20 Tage
250,00 €
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 11 bis 15 Tage
333,33 €
Details

CST6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-CST6 Antikörper

  1. Cow (Bovine) Polyclonal CST6 Primary Antibody für WB - ABIN2785432 : Veniaminova, Vagnozzi, Kopinke, Do, Murtaugh, Maillard, Dlugosz, Reiter, Wong: Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. in Development (Cambridge, England) 2013 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen CST6 Interaktionspartner

Human Cystatin E/M (CST6) Interaktionspartner

  1. Data suggest that melanoma cells internalize/absorb cystatin C (zeige CST3 Antikörper) from culture media, leading to increased intracellular cystatin C (zeige CST3 Antikörper) levels; cystatin E/M is internalized as well but at modest rate due to down-regulation of cell migration; however, the effect of intracellular cystatin E/M on down-regulation of legumain (zeige LGMN Antikörper) activity is pronounced.

  2. Results provide evidence that cystatin E/M is a tumor suppressor gene which plays an important role in the regulation of NF-kappaB (zeige NFKB1 Antikörper).

  3. Low CST6 expression is associated with breast cancer.

  4. Developed a Methylation-Sensitive High Resolution Melting Analysis (MS-HRMA) assay for the investigation of CST6 promoter methylation in breast cancer patients.CST6 promoter was methylated in 39/80 of FFPEs.

  5. The CST6 promoter is highly methylated in circulating cell-free DNA of breast cancer patients, but not in healthy individuals.

  6. Data show a regulatory role of cystatin E/M in controlling both intra- and extracellular legumain (zeige LGMN Antikörper) activity.

  7. The ectopic expression of CST6 in cancer cells rescued mice from overt osteolytic metastasis and deaths in the animal study, while CST6 knockdown markedly enhanced cancer cell bone metastasis and shortened animal survival.

  8. An association between the quantity of CST6 methylation and the expression statuses of estrogen receptor (zeige ESR1 Antikörper), progesterone receptor (zeige PGR Antikörper), and HER4 (zeige ERBB4 Antikörper) in tumor tissues was found

  9. the level of cystatin E/M regulates legumain (zeige LGMN Antikörper) activity and hence the invasive potential of human melanoma cells

  10. CST6 is not a major gene contributing to type 1 and 2 harlequin ichthyosis

Mouse (Murine) Cystatin E/M (CST6) Interaktionspartner

  1. Using quenched activity-based probes, we identified mouse cathepsin B (CtsB (zeige CTSB Antikörper)), which is expressed in the lower regions of the hair follicle, as an additional target of mouse Cst6

  2. conclude that a tightly regulated balance between cathepsin L (zeige CTSL1 Antikörper) and cystatin M/E is essential for tissue integrity in epidermis, hair follicles, and corneal epithelium

  3. cystatin M/E has a role in skin barrier formation and a potential role as a tumor suppressor gene [review]

CST6 Antigen-Profil

Protein Überblick

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Genbezeichner und Symbole assoziert mit anti-Cystatin E/M (CST6) Antikörper

  • cystatin E/M (CST6) Antikörper
  • cystatin E/M (Cst6) Antikörper
  • 1110017E11Rik Antikörper
  • CST6 Antikörper
  • ichq Antikörper
  • N28197 Antikörper

Bezeichner auf Proteinebene für anti-Cystatin E/M (CST6) Antikörper

cystatin E/M , cystatin M , cystatin-M , cystatin 6 , cystatin M/E , cystatin-6 , cystatin-E , cysteine proteinase inhibitor , harlequin ichthyosis , harlequin ichthysosis , cystatin N

GENE ID SPEZIES
466668 Pan troglodytes
503685 Bos taurus
714999 Macaca mulatta
1474 Homo sapiens
483719 Canis lupus familiaris
73720 Mus musculus
171096 Rattus norvegicus
Ausgewählte Anbieter für anti-CST6 (CST6) Antikörper
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