Complement Factor H-Related 2 Proteine (CFHR2)

Might be involved in complement regulation. Zusätzlich bieten wir Ihnen Complement Factor H-Related 2 Antikörper (23) und Complement Factor H-Related 2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CFHR2 3080 P36980
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Top Complement Factor H-Related 2 Proteine auf

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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
Human Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
Human Cells Human His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage

CFHR2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, ,

Weitere Proteine zu Complement Factor H-Related 2 (CFHR2) Interaktionspartnern

Human Complement Factor H-Related 2 (CFHR2) Interaktionspartner

  1. Next-generation sequencing of the CFH (zeige CFH Proteine) region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH (zeige CFH Proteine)-related genes in the retina or RPE (zeige RPE Proteine)/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR2]

  2. Studies indicate that complement factor H (zeige CFH Proteine)-related proteins (FHR1 (zeige CFHR1 Proteine)-5) may enhance complement activation, with important implications for the role of these proteins in disease.

  3. Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH (zeige CFH Proteine)/CFHR1 (zeige CFHR1 Proteine)-3 and complement factor H (zeige CFH Proteine) 479.

  4. Thus CFHR2 likely acts in concert with factor H (zeige CFH Proteine), as CFHR2 inhibits convertases while simultaneously allowing factor H (zeige CFH Proteine) assisted degradation by factor I.

  5. A hybrid CFHR2-CFHR5 (zeige CFHR5 Proteine) plasma protein, arising from a chromosomal deletion mutation stabilizes the C3 convertase and reduces factor H (zeige CFH Proteine)-mediated convertase decay.

Complement Factor H-Related 2 (CFHR2) Protein Überblick

Protein Überblick

Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.

Genbezeichner und Symbole assoziert mit CFHR2

  • complement factor H related 2 (CFHR2)
  • CFHL2 Protein
  • FHR2 Protein
  • HFL3 Protein

Bezeichner auf Proteinebene für CFHR2

DDESK59 , FHR-2 , H factor (complement)-like 3 , complement factor H-related protein 2 , factor H-related gene 2 , h factor-like 3 , h factor-like protein 2

3080 Homo sapiens
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