anti-Choline Kinase alpha (CHKA) Antikörper

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Zusätzlich bieten wir Ihnen Choline Kinase alpha Proteine (7) und Choline Kinase alpha Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CHKA 1119 P35790
CHKA 12660 O54804
CHKA 29194 Q01134
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Top anti-Choline Kinase alpha Antikörper auf antikoerper-online.de

Showing 10 out of 56 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CHKA Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Human Liver 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-CHK (ABIN392815) in HepG2 cell line lysate (35 µg/lane).CHK(arrow) was detected using the purified polyclonal antibody (1:40 dilution). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB The anti-CHK Pab is used in Western blot to detect CHK in mouse heart tissue lysate. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Maus Unkonjugiert ELISA, WB CHKA polyclonal antibody (A01), Lot # GPC1060208QCS1 Western Blot analysis of CHKA expression in A-431 . Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert WB CHKA antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
460,89 €
Details
Yeast Kaninchen Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
459,65 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: Choline kinase alpha Antibody [NBP1-85630] - Staining of human bronchus shows strong cytoplasmic positivity in mucous respiratory epithelial cells. Western Blot: Choline kinase alpha Antibody [NBP1-85630] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403943) 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details

CHKA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human
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Mouse (Murine)


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Rat (Rattus)


Am meisten referenzierte anti-Choline Kinase alpha Antikörper

  1. Human Polyclonal Choline Kinase alpha Primary Antibody für ELISA, WB - ABIN560360 : Vanpouille, Le Jeune, Kryza, Clotagatide, Janier, Dubois, Perek: Influence of multidrug resistance on (18)F-FCH cellular uptake in a glioblastoma model. in European journal of nuclear medicine and molecular imaging 2009 (PubMed)

Weitere Antikörper gegen Choline Kinase alpha Interaktionspartner

Human Choline Kinase alpha (CHKA) Interaktionspartner

  1. We found levels of CHKA to be increased in human HCCs (zeige HCCS Antikörper) compared to nontumor tissues, and increased expression to be associated with tumor aggressiveness. Overexpression of CHKA in HCC (zeige FAM126A Antikörper) cell lines increased their invasiveness, resistance to EGFR (zeige EGFR Antikörper) inhibitors, and ability to form metastatic tumors in mice by promoting interaction of EGFR (zeige EGFR Antikörper) with mechanistic target of rapamycin (zeige FRAP1 Antikörper) complex 2.

  2. Study shows increased CHKA expression in pancreatic ductal adenocarcinoma tumors and may be a predictive marker of response to chemotherapy.

  3. These data also support the approach of antitumor strategies that destabilize Chk-alpha protein or downregulate PtdCho in breast cancer treatment.

  4. Downregulation of choline kinase-alpha enhances autophagy in tamoxifen-resistant breast cancer cells.

  5. CHKA can act as an AR chaperone, providing, to our knowledge, the first evidence for kinases as molecular chaperones, making CHKA both a marker of tumor progression and a potential therapeutic target for PCa (zeige FLVCR1 Antikörper).

  6. Identify choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma.

  7. choline kinase alpha is inhibited by a near-infrared fluorescent carbocyanine

  8. Increased expression of CHKA is seen in malignant lesions of prostate cancer

  9. Chokalpha possessed oncogenic activity and could be a potential therapeutic target in T-cell lymphoma , as well as other hematological malignancies with interrupted Ras signaling pathways

  10. Downregulation of Chk-alpha with siRNA increased PLD1 expression, and downregulation of PLD1 increased Chk-alpha expression.

Mouse (Murine) Choline Kinase alpha (CHKA) Interaktionspartner

  1. hepatic phosphatidylcholine (zeige SGMS2 Antikörper) is regulated by the circadian clock through a Bmal1 (zeige ARNTL Antikörper)-Rev-erbalpha (zeige NR1D1 Antikörper)-Chkalpha axis

  2. Enforced expression of either CK(alpha) or CCTalpha (zeige PCYT1A Antikörper) increased the rate of synthesis and the amount of PtdCho, and these cells initiated neuronal differentiation.

  3. Lack of muscle degeneration in forelimbs of Chkb (zeige CHKB Antikörper)(-/-) mice is due to abundant choline kinase alpha and the stable homeostasis of phosphatidylcholine (zeige SGMS2 Antikörper).

  4. Experimental evidence for the presence of heteromeric ChoK/EtnK in any source. The activity of ChoK/EtnK in the cell is controlled not only by the level of each isoform but also by their combination to form the active oligomer complex.

  5. ChoK may have a role in carcinogenesis

  6. Data suggest that the choline kinase alpha promoter has a distal element (-875/-867) that binds c-jun (zeige JUN Antikörper) and the binding of c-jun (zeige JUN Antikörper) is enhanced by treatment with CCl4 (zeige CCL4 Antikörper).

  7. Chka is an essential gene for early embryonic development, but adult mice do not require full expression of the gene for normal levels of phosphatidylcholine (zeige SGMS2 Antikörper).

Choline Kinase alpha (CHKA) Antigen-Profil

Protein Überblick

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CHKA

  • choline kinase alpha (chka) Antikörper
  • choline kinase alpha (CHKA) Antikörper
  • choline kinase alpha (MCYG_00090) Antikörper
  • choline kinase (PF14_0020) Antikörper
  • choline kinase 1 (CK1) Antikörper
  • choline kinase (CNI01400) Antikörper
  • choline kinase alpha (Chka) Antikörper
  • ATCK1 Antikörper
  • Chetk-alpha Antikörper
  • Chk Antikörper
  • CHKA Antikörper
  • chkb Antikörper
  • ChoK Antikörper
  • CHOLINE KINASE Antikörper
  • choline kinase 1 Antikörper
  • CK Antikörper
  • CK-R Antikörper
  • CK/EK-alpha Antikörper
  • CKI Antikörper
  • EK Antikörper
  • EtnK-alpha Antikörper
  • F14O23.8 Antikörper
  • F14O23_8 Antikörper
  • im:7143625 Antikörper
  • si:dkey-12e7.3 Antikörper
  • wu:fd46h01 Antikörper

Bezeichner auf Proteinebene für CHKA

choline kinase alpha , choline kinase beta , choline kinase , CHETK-alpha , ethanolamine kinase , choline/ethanolamine kinase alpha , CK , EK , choline kinase R

GENE ID SPEZIES
558499 Danio rerio
476002 Canis lupus familiaris
514865 Bos taurus
451376 Pan troglodytes
496957 Xenopus (Silurana) tropicalis
9223440 Arthroderma otae CBS 113480
811591 Plasmodium falciparum 3D7
843500 Arabidopsis thaliana
3259492 Cryptococcus neoformans var. neoformans JEC21
100013074 Monodelphis domestica
100059839 Equus caballus
100566078 Anolis carolinensis
100587988 Nomascus leucogenys
423112 Gallus gallus
1119 Homo sapiens
12660 Mus musculus
29194 Rattus norvegicus
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