Age-Related Maculopathy Susceptibility 2 Proteine (ARMS2)

ARMS2 encodes a protein that is thought to play a role in diseases in the elderly. Zusätzlich bieten wir Ihnen ARMS2 Antikörper (20) und ARMS2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ARMS2 387715 P0C7Q2
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Top ARMS2 Proteine auf

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
HEK-293T Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage

ARMS2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,

Weitere Proteine zu Age-Related Maculopathy Susceptibility 2 (ARMS2) Interaktionspartnern

Human Age-Related Maculopathy Susceptibility 2 (ARMS2) Interaktionspartner

  1. The findings of the present study provide evidence that CFH (zeige CFH Proteine) gene variants and ARMS2/HTRA1 (zeige HTRA1 Proteine) genes play a major role in the genetic susceptibility to AMD (zeige AMD1 Proteine) in a Greek population. These findings are of direct relevance for disease and help mapping the genetic chart of AMD (zeige AMD1 Proteine).

  2. Development of polypoidal choroidal vasculopathy (PCV) in the unaffected fellow eye is associated with ARMS2 A69S genotype in patients with unilateral PCV.

  3. OCT (zeige Plxna2 Proteine) scans revealed lower retinal thickness in patients homozygous for CFH (zeige CFH Proteine) or ARMS2, which was caused by a significantly reduced photoreceptor layer. The number and ultrastructure of drusen were also significantly different.

  4. This study suggests that in familial age-related macular degeneration patients, the common genetic risk variant in ARMS2 is less important compared to sporadic age-related macular degeneration.

  5. this work we show that ARMS2 is externalized via an unconventional pathway bypassing Golgi.

  6. Interaction effects between supplement groups and individual complement factor H (CFH (zeige CFH Proteine)) Y402H and age-related maculopathy susceptibility 2 (ARMS2) genotypes, and composite genetic risk groups combining the number of risk alleles for both loci, were evaluated for their association with progression

  7. EMD (zeige EMD Proteine) were not AMD (zeige AMD1 Proteine)-independently associated with CFH (zeige CFH Proteine) or ARMS2 genotypes. Our results indicate that patients without AMD (zeige AMD1 Proteine) but with EMD (zeige EMD Proteine) can serve as controls in studies evaluating AMD (zeige AMD1 Proteine) risk factors.

  8. Variants in ARMS2 carry risk of age-related macular degeneration.

  9. CFH (zeige CFH Proteine), ARMS2, and C3 were associated with specific features of neovascularization at the time patients were enrolled in Comparison of Age-Related Macular Degeneration Treatments Trials .

  10. Subfoveal choroidal thickness and choroidal vascular hyperpermeability in eyes with treatment-naive polypoidal choroidal vasculopathy were associated with ARMS2 A69S (rs10490924) and CFH (zeige CFH Proteine) (rs1329428).

ARMS2 Protein Überblick

Protein Überblick

This gene encodes a protein that is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration.

Genbezeichner und Symbole assoziert mit ARMS2

  • age-related maculopathy susceptibility 2 (ARMS2)
  • ARMD8 Protein
  • ARMS2 Protein

Bezeichner auf Proteinebene für ARMS2

age-related maculopathy susceptibility protein 2 , age-related maculopathy susceptibility 2

387715 Homo sapiens
450791 Pan troglodytes
100271852 Macaca mulatta
Ausgewählte Anbieter für ARMS2 Proteine (ARMS2)
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