Activin Receptor Type I (ACRV1) ELISA Kits

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Zusätzlich bieten wir Ihnen Activin Receptor Type I Antikörper (170) und Activin Receptor Type I Proteine (35) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ACRV1 11477 P37172
ACRV1 90 Q04771
ACRV1 79558 P80201
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Top Activin Receptor Type I ELISA Kits auf

Showing 10 out of 16 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.063 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 15 bis 17 Tage
Human 0.063 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 8 bis 12 Tage
Maus 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Ratte 0.1 ng/mL 250-5000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Affe 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Meerschweinchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Hund 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für Activin Receptor Type I Interaktionspartner

Mouse (Murine) Activin Receptor Type I (ACRV1) Interaktionspartner

  1. Acute tacrolimus treatment transiently increases hepcidin (zeige HAMP ELISA Kits) in wild-type mice. FKBP12 (zeige FKBP1A ELISA Kits) preferentially targets the BMP receptor (zeige BMPR1A ELISA Kits) ALK2. ALK2 mutants defective in binding FKBP12 (zeige FKBP1A ELISA Kits) increase hepcidin (zeige HAMP ELISA Kits) expression in a ligand-independent manner, through BMP-SMAD (zeige SMAD1 ELISA Kits) signaling.

  2. The authors demonstrated that ubiquitin-specific protease (USP) 4 (zeige USP4 ELISA Kits) strongly induces activin (zeige Actbeta ELISA Kits)/BMP signaling by removing the inhibitory monoubiquitination from SMAD4 (zeige SMAD4 ELISA Kits).

  3. Enhanced SMAD (zeige SMAD1 ELISA Kits)-dependent BMP signaling through constitutively active ACVR1 in palatal epithelium causes submucous cleft palate in mice, via medial-edge-epithelium persistence presumably due to the up regulation of DeltaNp63 andresultingreductionofcaspase-3 activation. 2.

  4. BMP signaling mediated by coordination of ALK2/ACVR1, ALK3/BMPR1A (zeige BMPR1A ELISA Kits), and BMPR2 (zeige BMPR2 ELISA Kits) is an essential proangiogenic cue for retinal vessels.

  5. This study showed that Gja1 (zeige GJA1 ELISA Kits) may act downstream of cAMP-PKA signal to mediate the effects of Acvr1 on the differentiation of uterine stromal cells through targeting Hand2 (zeige HAND2 ELISA Kits).

  6. Results showed activin (zeige Actbeta ELISA Kits)-C and follistatin (zeige FST ELISA Kits) are differentially expressed during prostate development and suggested that the antagonistic property of follistatin (zeige FST ELISA Kits) is secondary to the action of activin (zeige Actbeta ELISA Kits)-C. Study provides evidence to support a role of activin (zeige Actbeta ELISA Kits)-C in prostate development and provides new insights in the spatiotemporal localization of activins and their antagonists during mouse prostate development.

  7. BMPR1B plays distinct roles from BMPR1A and ACVR1 in maintaining bone mass and transducing BMP signaling

  8. Suggest that BMP signaling upregulates the calcineurin/nuclear factor of activated T cell (zeige NFATC3 ELISA Kits) pathway via BMP type I receptor ALK2, contributing to cardiac hypertrophy and fibrosis.

  9. results suggest that ACVR1(R206H) causes FOP (zeige CHTOP ELISA Kits) by gaining responsiveness to the normally antagonistic ligand activin A (zeige INHBA ELISA Kits), demonstrating that this ligand is necessary and sufficient for driving HO in a genetically accurate model of FOP (zeige CHTOP ELISA Kits)

  10. The findings suggest that the mutant ALK2 related to Fibrodysplasia ossificans progressiva is enhanced by bone morphogenetic protein type II receptors via the T203-regulated phosphorylation of ALK2.

Human Activin Receptor Type I (ACRV1) Interaktionspartner

  1. both bone morphogenetic protein 2 (BMP2 (zeige BMP2 ELISA Kits)) and BMP6 (zeige BMP6 ELISA Kits) are proangiogenic in vitro and ex vivo and that the BMP type I receptors, activin receptor-like kinase 3 (ALK3 (zeige BMPR1A ELISA Kits)) and ALK2, play crucial and distinct roles in this process.

  2. Fibrodysplasia ossificans progressiva (FOP) syndrome is caused by mutation of the gene ACVR1. Developed is a simplified one-step procedure by simultaneously introducing reprogramming and gene-editing components into human fibroblasts derived from patient with FOP. The one-step-mediated ALK2 gene-corrected induced pluripotent stem cells restored global gene expression pattern.

  3. The ACVR1 R206H mutation may not directly increase the formation of mature chondrogenic or osteogenic cells.

  4. Authors demonstrated that the BMP type I receptor ALK-2 (encoded by the ACVR1 gene) has crucial roles in apoptosis induction of patient-derived glioma-initiating cells (GICs), TGS (zeige LIN9 ELISA Kits)-01 and TGS (zeige LIN9 ELISA Kits)-04.

  5. Data suggest BMP9/GDF2 (zeige GDF2 ELISA Kits) and BMP10 (zeige BMP10 ELISA Kits) synergize with TNFA (zeige TNF ELISA Kits) to increase monocyte recruitment to vascular endothelial cells; process appears to be mediated mainly via ALK2/ACVR1 (which exhibits protein kinase (zeige CDK7 ELISA Kits) activity). These studies used in vitro flow monocyte adhesion assay. (BMP9 (zeige GDF2 ELISA Kits) = growth differentiation factor 2 (zeige GDF2 ELISA Kits); BMP10 (zeige BMP10 ELISA Kits) = bone morphogenetic protein 10 (zeige BMP10 ELISA Kits); TNFA (zeige TNF ELISA Kits) = tumor necrosis factor alpha (zeige TNF ELISA Kits); ALK2/ACVR1 = activin A receptor type 1)

  6. The effects of ACVR1/ALK2 mutations causing fibrodysplasia ossificans progressiva are extended to the central nervous system. Brainstem hamartomatous lesions and dysmorphisms, variably associated with dentate nucleus and basal ganglia signal abnormalities and/or calcifications, may represent useful disease hallmarks.

  7. Low ALK2 expression is associated with invasiveness of breast cancer.

  8. Further investigation on clinical ESCC samples and non-tumorous adjacent tissue found that tumors with triple-positive BMP6 (zeige BMP6 ELISA Kits), ALK2 and BMPRII (zeige BMPR2 ELISA Kits) had deeper growth than tumors with only BMP6 (zeige BMP6 ELISA Kits) expression

  9. The clinical manifestations, the disease course, and the molecular findings of involvement of ACVR1 gene in this family are suggestive of "FOP variant" or an unusual ACVR1-related skeletal dysplasia

  10. Activin-A (zeige INHBA ELISA Kits) is increased in the airway of asthmatics and peaks during asthma exacerbations.Activin-A signalling pathways are dysregulated in severe asthma.

Activin Receptor Type I (ACRV1) Antigen-Profil

Beschreibung des Gens

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Genbezeichner und Symbole assoziert mit ACRV1

  • activin A receptor, type 1 (Acvr1) Antikörper
  • activin A receptor type 1 (ACVR1) Antikörper
  • activin A receptor type 1 (Acvr1) Antikörper
  • ActR-I Antikörper
  • ActR-IA Antikörper
  • ACTRI Antikörper
  • ActRIA Antikörper
  • Acvr Antikörper
  • ACVR1A Antikörper
  • ACVRLK2 Antikörper
  • Alk-2 Antikörper
  • ALK2 Antikörper
  • Alk8 Antikörper
  • D330013D15Rik Antikörper
  • FOP Antikörper
  • SKR1 Antikörper
  • Tsk7L Antikörper
  • TSRI Antikörper

Bezeichner auf Proteinebene für ACRV1

TGF-B superfamily receptor type I , TSK-7L , TSR-I , activin receptor type I , activin receptor type-1 , serine/threonine-protein kinase receptor R1 , activin A receptor, type II-like kinase 2 , activin receptor-like kinase 2 , hydroxyalkyl-protein kinase , ACTR-I , SKR1 , activin A receptor, type 1 , activin type I receptor , type I TGF B receptor , activin A receptor, type I , activin receptor type IA

11477 Mus musculus
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79558 Rattus norvegicus
395246 Gallus gallus
443161 Ovis aries
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