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May be required for neuronal cell differentiation.. Zusätzlich bieten wir Ihnen AHNAK Antikörper (52) und AHNAK Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
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Based on the findings, the authors designate the Chlamydia trachomatis gene product corresponding to ct694-ctl0063translocated membrane-associated effector A (TmeA). Overall, the data reveal a role of TmeA during chlamydial invasion that manifests independently of effects on AHNAK.
Examination of Gene Expression Omnibus database data sets suggests that downregulation of AHNAK mRNA and mutation of the AHNAK gene are common in metastatic melanoma and correlates to a poor outcome.
inhibition of Ahnak can promote generation of induced pluripotent stem cells (iPSC) via up-regulation of endogenous c-Myc (zeige MYC Proteine).
tetrandrine may inhibit the growth of Hep (zeige EPHB6 Proteine)-2 cells by decreasing the intracellular concentration of Ca2 (zeige CA2 Proteine)+ and upregulating the expressions of Brg1 (zeige SMARCA4 Proteine) and AHNAK
Authors show here that AnxA2 (zeige ANXA2 Proteine), p11 (zeige S100A10 Proteine) and AHNAK are required for type 3 secretion system-mediated Salmonella invasion of cultured epithelial cells.
High AHNAK expression is asociated with mesothelioma.
While the structure-based consensus sequence allows interactions with various stretches of the AHNAK C-terminal domain, comparison with other S100 structures reveals that the sequence has been optimized for binding to S100A10 (zeige S100A10 Proteine).
The AHNAK peptide adopts a coil conformation that arches across the heterotetramer contacting both annexin A2 (zeige ANXA2 Proteine) and S100A10 (zeige S100A10 Proteine) protomers with tight affinity.
these results define ahnak1 in muscle connective tissue as a novel feature of two genetically distinct muscular dystrophies that might contribute to disease pathology.
AHNAK constitutes a novel mechanism in post-transcriptional control of gene expression.
Ahnak1 plays a protective role in vascular healing after wire injuries.
Findings suggest an important role of AHNAK in the regulation of thermogenesis and lipolysis in white adipose tissue via beta-adrenergic signaling.
AHNAK plays a crucial role in body fat accumulation by regulating adipose tissue development via interaction with the SMAD1 (zeige SMAD1 Proteine) protein and can be involved in metabolic homeostasis
findings suggest that Ahnak might be involved in modulating the differentiation of newly generated cells into neuronal or non-neuronal cells
Results suggest that by interfering in the cross-talk between the transmembrane form of the laminin receptor dystroglycan and F-actin, AHNAK1 influences the cytoskeleton organization of Schwann cells
Ahnak mediates a negative regulation of cell growth and acts as novel tumor suppressor through potentiation of TGFB (zeige TGFB1 Proteine) signaling.
Ahnak protein plays an important scaffolding function connecting Erk (zeige EPHB2 Proteine) and Rac (zeige AKT1 Proteine) activation in PDGF (zeige PDGFA Proteine)-dependent migration of aortic smooth muscle cells (ASMC).
phosphorylation event is one mechanism underlying ahnak1's modulator function on Cav1.2 (zeige CACNA1C Proteine) channel activity.
these results indicate that ahnak1 is not essential for beta-adrenergic up-regulation of I (CaL (zeige S100A11 Proteine)) and cardiac contractility in mice.
May be required for neuronal cell differentiation.
, neuroblast differentiation-associated protein AHNAK
, AHNAK nucleoprotein
, AHNAK nucleoprotein (desmoyokin)