anti-Schwein p107 Antikörper für Western Blotting

Recommended p107 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Retinoblastoma-Like 1 (p107) (RBL1) Antikörper
  • p107
  • prb1
  • fj58e06
  • wu:fj58e06
  • CP107
  • PRB1
  • AW547426
  • retinoblastoma-like 1 L homeolog
  • RB transcriptional corepressor like 1
  • retinoblastoma-like 1 (p107)
  • retinoblastoma-like 1
  • rbl1.L
  • RBL1
  • rbl1
  • Rbl1
Epitop
Middle Region
20
16
14
10
8
3
3
3
2
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
105
58
47
4
4
4
3
3
2
2
1
1
1
Wirt
Kaninchen
96
9
Klonalität
Polyklonal
Konjugat
Dieser p107 Antikörper ist unkonjugiert
6
6
6
4
4
4
2
2
2
2
2
2
2
2
2
2
2
Applikation
Western Blotting (WB)
68
45
27
22
16
12
4
3
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2779679
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2908103 ABIN2792553 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN470427 WB Rabbit AA 143-192 Anmelden zum Anzeigen Polyclonal 0
1 ABIN467760 WB Rabbit AA 935-984 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2627530 IHC (p) WB Rabbit IgG AA 1048-1068 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Retinoblastoma-Like 1 (p107) (RBL1) Antikörper
Epitop Middle Region
(20), (16), (14), (10), (8), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
(105), (58), (47), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1)
Wirt Kaninchen
(96), (9)
Klonalität
Polyklonal
Konjugat Dieser p107 Antikörper ist unkonjugiert
(6), (6), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Western Blotting (WB)
(68), (45), (27), (22), (16), (12), (4), (3), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p107 Antikörper

Target Details p107 Anwendungsinformationen Handhabung Referenzen für anti-p107 Antikörper (ABIN2779679) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982719.
Sequenz NTIYVGRVKS FALKYDLANQ DHMMDAPPLS PFPHIKQQPG SPRRISQQHS
Homologie Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against RBL1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human RBL1

Target Details p107

Produktdetails anti-p107 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-p107 Antikörper (ABIN2779679) Bilder zurück nach oben
Antigen
Andere Bezeichnung RBL1 (RBL1 Antibody Abstract)
Hintergrund RBL1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor.The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CP107, MGC40006, PRB1, p107
Protein Interaction Partner: DYRK1B, DYRK1A, CDK2, MAGEA11, E2F1, AR, UBC, RBBP8, E2F4, PLSCR1, NUCB1, LAMB2, NR4A1, GOLGA2, FN1, EPHA2, CDK6, CDK4, AOX1, SP1, SNRPD3, DGKZ, ID2, RINT1, E2F3, E2F2, PPP1CA, TOP1, SMARCA4, CCNA2, LIN9, LIN54, LIN37, MYBL2, MAPK6, IRF3, RBL2, DHX30, NR2
Protein Size: 1068
Molekulargewicht 121 kDa
Gen-ID 5933
NCBI Accession NM_002895, NP_002886
UniProt P28749
Pathways Zellzyklus, Mitotic G1-G1/S Phases

Anwendungsinformationen

Produktdetails anti-p107 Antikörper Target Details p107 Handhabung Referenzen für anti-p107 Antikörper (ABIN2779679) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1068 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p107 Antikörper Target Details p107 Anwendungsinformationen Referenzen für anti-p107 Antikörper (ABIN2779679) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-p107 Antikörper (ABIN2779679)

Produktdetails anti-p107 Antikörper Target Details p107 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Ross, Tsang, Shewmake, McGehee: "Expression of p107 and p130 during human adipose-derived stem cell adipogenesis." in: Biochemical and biophysical research communications, Vol. 366, Issue 4, pp. 927-31, 2008

Bilder

Produktdetails anti-p107 Antikörper Target Details p107 Anwendungsinformationen Handhabung Referenzen für anti-p107 Antikörper (ABIN2779679) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Retinoblastoma-Like 1 (p107) (RBL1) (Middle Region) antibody (ABIN2779679) anti-Retinoblastoma-Like 1 (p107) (RBL1) (Middle Region) antibody