anti-Hund GADD45B Antikörper für Western Blotting

Recommended GADD45B Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Antikörper
  • CS131
  • cb196
  • gadd45b
  • gadd45b2
  • sb:cb196
  • zgc:73104
  • gadd45beta
  • wu:fa92d10
  • wu:fa98h12
  • wu:fk65h03
  • zgc:111973
  • AI323528
  • Myd118
  • GADD45BETA
  • MYD118
  • growth arrest and DNA-damage-inducible, beta a
  • growth arrest and DNA damage inducible beta
  • growth arrest and DNA-damage-inducible 45 beta
  • growth arrest and DNA-damage-inducible, beta
  • gadd45ba
  • GADD45B
  • Gadd45b
Epitop
Middle Region
7
2
2
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Ratte (Rattus)
40
28
26
5
2
Wirt
Kaninchen
40
Klonalität
Polyklonal
Konjugat
Dieser GADD45B Antikörper ist unkonjugiert
3
3
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
16
14
13
13
5
4
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2783334
$ 319.00
Zzgl. Versandkosten $45.00

General

Antigen Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Antikörper
Epitop Middle Region
(7), (2), (2), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Ratte (Rattus)
(40), (28), (26), (5), (2)
Wirt Kaninchen
(40)
Klonalität
Polyklonal
Konjugat Dieser GADD45B Antikörper ist unkonjugiert
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(16), (14), (13), (13), (5), (4), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GADD45B Antikörper

Target Details GADD45B Anwendungsinformationen Handhabung Referenzen für anti-GADD45B Antikörper (ABIN2783334) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977232.
Sequenz FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against GADD45B. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human GADD45B
Plasmids, Primers & others

Target Details GADD45B

Produktdetails anti-GADD45B Antikörper Anwendungsinformationen Handhabung Referenzen für anti-GADD45B Antikörper (ABIN2783334) Bilder zurück nach oben
Antigen
Andere Bezeichnung GADD45B (GADD45B Antibody Abstract)
Hintergrund The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZP566B133, GADD45BETA, MYD118
Protein Interaction Partner: UBD, UBC, MAP3K4, GADD45GIP1, GADD45G, MAP2K7, MAP3K5, PPARG, PPARD, PCNA, PPARA, ESR1, CCNB1, CDK1, CDKN1A, GADD45A, EGR1,
Protein Size: 160
Molekulargewicht 18 kDa
Gen-ID 4616
NCBI Accession NM_015675, NP_056490
UniProt O75293
Pathways Zellzyklus

Anwendungsinformationen

Produktdetails anti-GADD45B Antikörper Target Details GADD45B Handhabung Referenzen für anti-GADD45B Antikörper (ABIN2783334) Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 160 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GADD45B Antikörper Target Details GADD45B Anwendungsinformationen Referenzen für anti-GADD45B Antikörper (ABIN2783334) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GADD45B Antikörper (ABIN2783334)

Produktdetails anti-GADD45B Antikörper Target Details GADD45B Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Ursini, Cavalleri, Fazio, Angrisano, Iacovelli, Porcelli, Maddalena, Punzi, Mancini, Gelao, Romano, Masellis, Calabrese, Rampino, Taurisano, Di Giorgio, Keller, Tarantini, Sinibaldi, Quarto et al.: "BDNF rs6265 methylation and genotype interact on risk for schizophrenia. ..." in: Epigenetics, Vol. 11, Issue 1, pp. 11-23, 2016

Gavin, Kusumo, Zhang, Guidotti, Pandey: "Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors." in: Alcoholism, clinical and experimental research, Vol. 40, Issue 2, pp. 263-72, 2016

Matrisciano, Dong, Gavin, Nicoletti, Guidotti: "Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain." in: Molecular pharmacology, Vol. 80, Issue 1, pp. 174-82, 2011

Gavin, Sharma, Chase, Matrisciano, Dong, Guidotti: "Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 2, pp. 531-42, 2011

Tornatore, Marasco, Dathan, Vitale, Benedetti, Papa, Franzoso, Ruvo, Monti: "Gadd45 beta forms a homodimeric complex that binds tightly to MKK7." in: Journal of molecular biology, Vol. 378, Issue 1, pp. 97-111, 2008

Bilder

Produktdetails anti-GADD45B Antikörper Target Details GADD45B Anwendungsinformationen Handhabung Referenzen für anti-GADD45B Antikörper (ABIN2783334) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) WB Suggested Anti-GADD45B Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 ...
Western Blotting (WB) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) Host: Mouse Target Name: GADD45B Sample Tissue: Mouse Small Intestine Antibody ...
Western Blotting (WB) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) Host: Rabbit Target Name: GA45B Sample Type: Fetal Lung lysates Antibody Diluti...
Immunohistochemistry (IHC) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (Image 4)
Western Blotting (WB) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) Host: Rabbit Target Name: GADD45B Sample Tissue: Human Lung Tumor Antibody Dilu...
Western Blotting (WB) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) Host: Rabbit Target Name: GADD45B Sample Tissue: Human Jurkat Whole Cell Antibo...
Immunohistochemistry (IHC) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (Image 7)
Immunohistochemistry (IHC) image for anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (ABIN2783334) anti-Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) (Middle Region) antibody (Image 8)