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  • ELISA Kit Sensitivity
    The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
  • ELISA Kit Specificity
    The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
  • Experiement Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
  • ELISA Kit Robustness
    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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E2F4 Antigen Profile

Beschreibung des Gens

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

Alternative names and synonyms associated with E2F4

  • E2F transcription factor 4 (E2F4) ELISA Kit
  • E2F transcription factor 4 (E2f4) ELISA Kit
  • E2F transcription factor 4 S homeolog (e2f4.S) ELISA Kit
  • E2F transcription factor 4 (e2f4) ELISA Kit
  • E2F-4 ELISA Kit
  • 2010111M04Rik ELISA Kit
  • AI427446 ELISA Kit
  • E2F4 ELISA Kit
  • e2f-4 ELISA Kit
  • fb72f07 ELISA Kit
  • wu:fb72f07 ELISA Kit
  • wu:fe05f06 ELISA Kit
  • zgc:63815 ELISA Kit

Bezeichner auf Proteinebene für E2F4

p107/p130-binding protein , transcription factor E2F4 , E2F-4 , E2F transcription factor 4, p107/p130-binding , E2F transcription factor 4

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